3lch

<StructureSection load='3lch' size='340' side='right' caption='[[3lch]], [[Resolution|resolution]] 2.04&Aring;' scene=''>

<table><tr><td colspan='2'>[[3lch]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LCH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3LCH FirstGlance]. <br>

</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>

<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1nal|1nal]], [[3lbc|3lbc]], [[3lbm|3lbm]], [[3lcf|3lcf]], [[3lcg|3lcg]], [[3lci|3lci]], [[3lcl|3lcl]], [[3lcw|3lcw]], [[3lcx|3lcx]]</td></tr>

<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">b3225, JW3194, nanA, npl ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI])</td></tr>

<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/N-acetylneuraminate_lyase N-acetylneuraminate lyase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.3.3 4.1.3.3] </span></td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3lch FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3lch OCA], [http://pdbe.org/3lch PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3lch RCSB], [http://www.ebi.ac.uk/pdbsum/3lch PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3lch ProSAT]</span></td></tr>

[[http://www.uniprot.org/uniprot/NANA_ECOLI NANA_ECOLI]] Catalyzes the cleavage of N-acetylneuraminic acid (sialic acid) to form pyruvate and N-acetylmannosamine via a Schiff base intermediate.[HAMAP-Rule:MF_01237]