This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
3mnq
From Proteopedia
| Line 1: | Line 1: | ||
==Crystal structure of myosin-2 motor domain in complex with ADP-metavanadate and resveratrol== | ==Crystal structure of myosin-2 motor domain in complex with ADP-metavanadate and resveratrol== | ||
| - | <StructureSection load='3mnq' size='340' side='right' caption='[[3mnq]], [[Resolution|resolution]] 2.20Å' scene=''> | + | <StructureSection load='3mnq' size='340' side='right'caption='[[3mnq]], [[Resolution|resolution]] 2.20Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3mnq]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[3mnq]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Dictyostelium_discoideum_ax4 Dictyostelium discoideum ax4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MNQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3MNQ FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=AD9:ADP+METAVANADATE'>AD9</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=STL:RESVERATROL'>STL</scene></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AD9:ADP+METAVANADATE'>AD9</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=STL:RESVERATROL'>STL</scene></td></tr> |
| - | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2jhr|2jhr]], [[2jj9|2jj9]], [[1fmv|1fmv]], [[1fmw|1fmw]], [[1mma|1mma]], [[1mmd|1mmd]], [[1mmg|1mmg]], [[1mmn|1mmn]], [[1mnd|1mnd]], [[1vom|1vom]], [[1w9i|1w9i]], [[1w9j|1w9j]], [[1yv3|1yv3]], [[3fts|3fts]], [[3ftu|3ftu]], [[3ckl|3ckl]], [[2jiz|2jiz]], [[1z1f|1z1f]], [[1sg0|1sg0]], [[1u0w|1u0w]], [[1dvs|1dvs]], [[1cgz|1cgz]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2jhr|2jhr]], [[2jj9|2jj9]], [[1fmv|1fmv]], [[1fmw|1fmw]], [[1mma|1mma]], [[1mmd|1mmd]], [[1mmg|1mmg]], [[1mmn|1mmn]], [[1mnd|1mnd]], [[1vom|1vom]], [[1w9i|1w9i]], [[1w9j|1w9j]], [[1yv3|1yv3]], [[3fts|3fts]], [[3ftu|3ftu]], [[3ckl|3ckl]], [[2jiz|2jiz]], [[1z1f|1z1f]], [[1sg0|1sg0]], [[1u0w|1u0w]], [[1dvs|1dvs]], [[1cgz|1cgz]]</div></td></tr> |
| - | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">mhcA, DDB_G0286355 ([ | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">mhcA, DDB_G0286355 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=352472 Dictyostelium discoideum AX4])</td></tr> |
| - | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Myosin_ATPase Myosin ATPase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.4.1 3.6.4.1] </span></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3mnq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3mnq OCA], [https://pdbe.org/3mnq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3mnq RCSB], [https://www.ebi.ac.uk/pdbsum/3mnq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3mnq ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/MYS2_DICDI MYS2_DICDI]] Myosin is a protein that binds to actin and has ATPase activity that is activated by actin. |
| + | |||
| + | ==See Also== | ||
| + | *[[Heat Shock Protein structures|Heat Shock Protein structures]] | ||
| + | *[[Myosin 3D Structures|Myosin 3D Structures]] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Dictyostelium discoideum ax4]] | [[Category: Dictyostelium discoideum ax4]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Myosin ATPase]] | [[Category: Myosin ATPase]] | ||
[[Category: Backhaus, A]] | [[Category: Backhaus, A]] | ||
Revision as of 13:48, 4 May 2022
Crystal structure of myosin-2 motor domain in complex with ADP-metavanadate and resveratrol
| |||||||||||
Categories: Dictyostelium discoideum ax4 | Large Structures | Myosin ATPase | Backhaus, A | Baruch, P | Fedorov, R | Manstein, D J | Schneider, J | Taft, M | Actin-binding | Activator | Allosteric | Atp-binding | Calmodulin-binding | Contractile protein | Inhibitor | Motor domain | Motor protein | Motor protein-inhibitor complex | Myosin | Nucleotide-binding | Phosphoprotein | Resveratrol
