User:Arthur Migliatti/Sandbox1
From Proteopedia
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You may include any references to papers as in: the use of JSmol in Proteopedia <ref>DOI 10.1002/ijch.201300024</ref> or to the article describing Jmol <ref>PMID:21638687</ref> to the rescue. | You may include any references to papers as in: the use of JSmol in Proteopedia <ref>DOI 10.1002/ijch.201300024</ref> or to the article describing Jmol <ref>PMID:21638687</ref> to the rescue. | ||
| - | '''Thioredoxin'''(Trx) is a protein present in a large amount of organisms, from bacterias to complex organisms as humans. It interacts with a diverse pool of proteins, acting, when reduced, as a donator of a pair of electrons, and becomes oxidized. It is reduced back by '''Thioredoxin Reductase'''(TrxR), which is reduced in the end by '''NADPH''' <ref>https://doi.org/10.1016/j.freeradbiomed.2013.07.036</ref>. Trx and TrxR were first discovered in 1964 in a study realized in bacteria, and were described as necessary proteins to reduce '''Ribonucleotide Reductase'''(RNR), an enzyme involved in DNA replication and repair. | + | '''Thioredoxin'''(Trx) is a protein present in a large amount of organisms, from bacterias to complex organisms as humans. It interacts with a diverse pool of proteins, acting, when reduced, as a donator of a pair of electrons, and becomes oxidized. It is reduced back by '''Thioredoxin Reductase'''(TrxR), which is reduced in the end by '''NADPH''' <ref>https://doi.org/10.1016/j.freeradbiomed.2013.07.036</ref>. Trx and TrxR were first discovered in 1964 in a study realized in bacteria, and were described as necessary proteins to reduce '''[[Ribonucleotide Reductase]]'''(RNR), an enzyme involved in DNA replication and repair. |
== Structure == | == Structure == | ||
Revision as of 13:38, 9 May 2022
Introduction
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References
- ↑ Hanson, R. M., Prilusky, J., Renjian, Z., Nakane, T. and Sussman, J. L. (2013), JSmol and the Next-Generation Web-Based Representation of 3D Molecular Structure as Applied to Proteopedia. Isr. J. Chem., 53:207-216. doi:http://dx.doi.org/10.1002/ijch.201300024
- ↑ Herraez A. Biomolecules in the computer: Jmol to the rescue. Biochem Mol Biol Educ. 2006 Jul;34(4):255-61. doi: 10.1002/bmb.2006.494034042644. PMID:21638687 doi:10.1002/bmb.2006.494034042644
- ↑ https://doi.org/10.1016/j.freeradbiomed.2013.07.036
