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3nk4
From Proteopedia
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<StructureSection load='3nk4' size='340' side='right'caption='[[3nk4]], [[Resolution|resolution]] 2.00Å' scene=''> | <StructureSection load='3nk4' size='340' side='right'caption='[[3nk4]], [[Resolution|resolution]] 2.00Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3nk4]] is a 4 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[3nk4]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Chick Chick]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NK4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3NK4 FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=A2G:N-ACETYL-2-DEOXY-2-AMINO-GALACTOSE'>A2G</scene>, <scene name='pdbligand=FLC:CITRATE+ANION'>FLC</scene></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A2G:N-ACETYL-2-DEOXY-2-AMINO-GALACTOSE'>A2G</scene>, <scene name='pdbligand=FLC:CITRATE+ANION'>FLC</scene></td></tr> |
| - | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3d4c|3d4c]], [[3d4g|3d4g]], [[3ef7|3ef7]], [[3nk3|3nk3]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3d4c|3d4c]], [[3d4g|3d4g]], [[3ef7|3ef7]], [[3nk3|3nk3]]</div></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3nk4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3nk4 OCA], [https://pdbe.org/3nk4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3nk4 RCSB], [https://www.ebi.ac.uk/pdbsum/3nk4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3nk4 ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/ZP3_CHICK ZP3_CHICK]] Component of the zona pellucida, which mediates species-specific sperm binding. Directly binds to sperm. Important for egg fertilization.<ref>PMID:15115720</ref> <ref>PMID:20970175</ref> |
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
Revision as of 07:03, 12 May 2022
Crystal structure of full-length sperm receptor ZP3 at 2.0 A resolution
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Categories: Chick | Large Structures | Jovine, L | Monne, M | Biodiversity | Cell adhesion | Core-1 | Egg coat | Egg-sperm interaction | Ehp | External hydrophobic patch | Extracellular matrix | Fertilization | Glycoprotein | Ihp | Immunoglobulin-like fold | Infertility | Internal hydrophobic patch | O-linked carbohydrate | Oocyte | Receptor | Secreted | Speciation | Species-specific gamete recognition | Sperm-combining site | T-antigen | Transmembrane | Vitelline envelope | Zona pellucida | Zp domain | Zp module
