3o63
From Proteopedia
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==Crystal Structure of Thiamin Phosphate Synthase from Mycobacterium tuberculosis== | ==Crystal Structure of Thiamin Phosphate Synthase from Mycobacterium tuberculosis== | ||
| - | <StructureSection load='3o63' size='340' side='right' caption='[[3o63]], [[Resolution|resolution]] 2.35Å' scene=''> | + | <StructureSection load='3o63' size='340' side='right'caption='[[3o63]], [[Resolution|resolution]] 2.35Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3o63]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[3o63]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_tuberculosis"_(zopf_1883)_klein_1884 "bacillus tuberculosis" (zopf 1883) klein 1884]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3O63 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3O63 FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> |
| - | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MT0427, MTCY22G10.11c, Rv0414c, thiE ([ | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MT0427, MTCY22G10.11c, Rv0414c, thiE ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1773 "Bacillus tuberculosis" (Zopf 1883) Klein 1884])</td></tr> |
| - | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Thiamine-phosphate_diphosphorylase Thiamine-phosphate diphosphorylase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.3 2.5.1.3] </span></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3o63 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3o63 OCA], [https://pdbe.org/3o63 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3o63 RCSB], [https://www.ebi.ac.uk/pdbsum/3o63 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3o63 ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/THIE_MYCTU THIE_MYCTU]] Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).<ref>PMID:21818324</ref> |
| + | |||
| + | ==See Also== | ||
| + | *[[Thiamin phosphate synthase|Thiamin phosphate synthase]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
[[Category: Thiamine-phosphate diphosphorylase]] | [[Category: Thiamine-phosphate diphosphorylase]] | ||
[[Category: Begley, T P]] | [[Category: Begley, T P]] | ||
Revision as of 07:16, 12 May 2022
Crystal Structure of Thiamin Phosphate Synthase from Mycobacterium tuberculosis
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