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Transducin 3D structures

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Line 6: Line 6:
*Transducin-α
*Transducin-α
 +
**[[7bph]] – hTDN + GN13 + GPPNP - human<br />
**[[1tnd]] – bTDN + GTPγS - bovine<br />
**[[1tnd]] – bTDN + GTPγS - bovine<br />
**[[1tag]] – bTDN + GDP<br />
**[[1tag]] – bTDN + GDP<br />
Line 14: Line 15:
**[[7jsn]] – bTDN (mutant) + phosphodiesterase + GTP + Levitra – Cryo EM<br />
**[[7jsn]] – bTDN (mutant) + phosphodiesterase + GTP + Levitra – Cryo EM<br />
-
*Transducin-β
+
*Transducin-b
-
**[[6n9g]] – TDN + RGS7 - mouse<br />
+
**[[7ewp]], [[7ewr]] – hTDN + RGS7 + GPR158<br />
 +
**[[6n9g]] – mTDN + RGS7 - mouse<br />
 +
**[[7shf]] – mTDN + RGS7 – Cryo EM<br />
*Transducin-βγ
*Transducin-βγ
-
**[[5he0]], [[5he1]], [[5he2]], [[5he3]], [[5ukk]], [[5ukl]], [[5ukm]], [[7k7z]], [[7k7l]] – hTDN + β-adrenergic receptor kinase 1 + inhibitor<br />
+
**[[5he0]], [[5he1]], [[5he2]], [[5he3]], [[7k7z]], [[7k7l]], [[7pwd]] – hTDN + β-adrenergic receptor kinase 1 + inhibitor <br />
**[[4kfm]] – hTDN + G-protein activated inward rectifier K+ channel<br />
**[[4kfm]] – hTDN + G-protein activated inward rectifier K+ channel<br />
**[[6m8s]] – hTDN + KCTD12<br />
**[[6m8s]] – hTDN + KCTD12<br />
 +
**[[7sf7]], [[7fs8]] – hTDN + adhesion GPC receptor + G protein subunit 13 – Cryo EM<br />
**[[6nbi]], [[6nbh]], [[6nbf]] – hTDN + PTH/PTHRP + long-acting parathyroid hormone + GS protein a subunit + nanobody – Cryo EM<br />
**[[6nbi]], [[6nbh]], [[6nbf]] – hTDN + PTH/PTHRP + long-acting parathyroid hormone + GS protein a subunit + nanobody – Cryo EM<br />
-
**[[4pnk]] – h/bTDN + bγ (mutant)+ β-adrenergic receptor kinase 1 + inhibitor<br />
 
**[[1tbg]] – bTDN <br />
**[[1tbg]] – bTDN <br />
**[[2trc]], [[1a0r]], [[1b9x]], [[1b9y]] – bTDN + phosducin<br />
**[[2trc]], [[1a0r]], [[1b9x]], [[1b9y]] – bTDN + phosducin<br />
Line 31: Line 34:
**[[3psc]], [[3pvu]], [[3pvw]], [[4mk0]] – bTDN + β-adrenergic receptor kinase 1<br />
**[[3psc]], [[3pvu]], [[3pvw]], [[4mk0]] – bTDN + β-adrenergic receptor kinase 1<br />
**[[6u7c]], [[6c2y]], [[5ukk]], [[5ukl]], [[5ukm]] – bTDN + β-adrenergic receptor kinase 1 + inhibitor<br />
**[[6u7c]], [[6c2y]], [[5ukk]], [[5ukl]], [[5ukm]] – bTDN + β-adrenergic receptor kinase 1 + inhibitor<br />
 +
**[[4pnk]] – TDN hb + bc (mutant)+ β-adrenergic receptor kinase 1 + inhibitor<br />
**[[2bcj]] – bTDN (mutant) + β-adrenergic receptor kinase 1<br />
**[[2bcj]] – bTDN (mutant) + β-adrenergic receptor kinase 1<br />
**[[3uzs]] – bTDN + β-adrenergic receptor kinase 1 + RNA<br />
**[[3uzs]] – bTDN + β-adrenergic receptor kinase 1 + RNA<br />
-
**[[3krw]], [[3krx]], [[6c2y]], [[5wg5]], [[5wg4]], [[5wg3]] – bTDN + G-protein coupled receptor kinase 2 + inhibitor<br />
+
**[[3krw]], [[3krx]], [[5wg5]], [[5wg4]], [[5wg3]] – bTDN + G-protein coupled receptor kinase 2 + inhibitor<br />
**[[1xhm]] – bTDN + peptide<br />
**[[1xhm]] – bTDN + peptide<br />
**[[6pcv]] – bTDN + RAC exchanger – Cryo EM<br />
**[[6pcv]] – bTDN + RAC exchanger – Cryo EM<br />
-
**[[6b20]] – bTDN + nanobody<br />
+
**[[6b20]] – bTDN + nanobody<br />
**[[6rmv]] – mTDN + channel peptide<br />
**[[6rmv]] – mTDN + channel peptide<br />
-
*Transducin-α+βγ
+
*Transducin-α+βγ binary complex
**[[6eg8]] – hTDN + GDP<br />
**[[6eg8]] – hTDN + GDP<br />
-
**[[6ddf]], [[6dde]] – hTDN + mu opioid receptor + DAMGO – Cryo EM<br />
 
**[[6d9h]] – hTDN + AChR/adenosine receptor – Cryo EM<br />
**[[6d9h]] – hTDN + AChR/adenosine receptor – Cryo EM<br />
 +
**[[6g79]], [[7e2x]], [[7e32]], [[7e33]] – hTDN + serotonin receptor – Cryo EM<br />
 +
**[[7d76]], [[7wu4]], [[7wu5]] – hTDN + adhesion GPC receptor – Cryo EM<br />
 +
**[[7mts]] – hTDN + glutamate receptor – Cryo EM<br />
 +
**[[7vh0]] – hTDN + melatonin receptor – Cryo EM<br />
 +
**[[7f1q]], [[7f1r]], [[7f1s]] – hTDN + chemokine receptor – Cryo EM<br />
 +
**[[7fig]], [[7fih]], [[7fii]] – bTDN + leutinizing hormone/choriogonadotropin receptor – Cryo EM<br />
 +
**[[1got]] – bTDN + GDP<br />
 +
 +
*Transducin-α+βγ ternary complex
 +
 +
**[[6ddf]], [[6dde]] – hTDN + mu opioid receptor + DAMGO – Cryo EM<br />
**[[6p9x]] – hTDN + CRFR-1 + corticliberin – Cryo EM<br />
**[[6p9x]] – hTDN + CRFR-1 + corticliberin – Cryo EM<br />
**[[6osa]] – hTDN + NTR1 + JMV449 – Cryo EM<br />
**[[6osa]] – hTDN + NTR1 + JMV449 – Cryo EM<br />
-
**[[6g79]] – hTDN + serotonin receptor – Cryo EM<br />
+
**[[7e2z]] – hTDN + serotonin receptor + drug – Cryo EM<br />
 +
**[[7e2y]] – hTDN + serotonin receptor + serotonin – Cryo EM<br />
 +
**[[7l0p]], [[7l0q]], [[7l0r]], [[7l0s]] – hTDN + neurotensin receptor + neurotensin – Cryo EM<br />
 +
**[[7lci]] – hTDN + glucagon-like peptide receptor + inhibitor – Cryo EM<br />
 +
**[[7f1r]], [[7f1s]] – hTDN + chemokine receptor – Cryo EM<br />
 +
**[[7mby]] – hTDN + cholecystokinin receptor + cholecystokinin – Cryo EM<br />
 +
**[[7f6i]] – hTDN + bradykinin receptor + kallidin + cholesterol – Cryo EM<br />
 +
**[[7f6h]] – hTDN + bradykinin receptor + bradykinin + cholesterol – Cryo EM<br />
 +
**[[7eib]] – hTDN + bradykinin receptor + polypeptide – Cryo EM<br />
 +
**[[7f8w]] – hTDN + cholecystokinin receptor + gastrin – Cryo EM<br />
 +
**[[7t6u]], [[7t6v]], [[7t6t]], [[7wvv]], [[7wvw]] – hTDN + formyl peptide receptor + peptide agonist – Cryo EM<br />
 +
**[[7wvy]] – hTDN + formyl peptide receptor + amyloid-beta A4 – Cryo EM<br />
 +
**[[7wvx]] – hTDN + formyl peptide receptor + humanin – Cryo EM<br />
 +
**[[7ld4]] – hTDN + adenosine A2A receptor + adenosine – Cryo EM<br />
 +
**[[7ld3]] – hTDN + adenosine A2A receptor + adenosine + agonist – Cryo EM<br />
 +
**[[7td3]] – hTDN + sphingosine receptor + sphingosine – Cryo EM<br />
 +
**[[7td4]] – bTDN + sphingosine receptor + drug – Cryo EM<br />
**[[6oy9]] – bTDN + rhodopsin + retinal – Cryo EM<br />
**[[6oy9]] – bTDN + rhodopsin + retinal – Cryo EM<br />
-
**[[6oya]] – bTDN + antibody + rhodopsin + retinal – Cryo EM<br />
+
**[[7s0f]], [[7s0g]] – bTDN + adrenergic receptor + drug – Cryo EM<br />
-
**[[1got]] – bTDN + GDP<br />
+
**[[7td0]], [[7td1]], [[7td2]] – bTDN + lysophosphatidic receptor + lysophosphatidic acid – Cryo EM<br />
-
**[[1gp2]], [[5kdo]], [[1gg2]] – r/bTDN + GDP - rat<br />
+
**[[1gg2]] – rTDN (mutant) + bbc + GDP - rat<br />
-
**[[3ah8]] – r/bTDN (mutant) + GDP + inhibitor<br />
+
**[[1gp2]], [[5kdo]] – rTDN + bbc + GDP <br />
-
**[[5tdh]] – h/r/bTDN (mutant) + GDP<br />
+
**[[3ah8]] – rTDN + bb + bc (mutant) + GDP + inhibitor<br />
 +
**[[5tdh]] – h/rTDN (mutant) + rb + bc + GDP<br />
-
*Transducin-α+βγ ternary complex with antibody
+
*Transducin-α+βγ ternary complex with scFv
-
**[[6pt0]], [[6n4b]], [[6kpg]], [[6kpf]] – hTDN + cannaboid receptor + antibody fragment – Cryo EM<br />
+
**[[6pt0]], [[6n4b]], [[6kpg]], [[6kpf]] – hTDN + cannaboid receptor + scFv – Cryo EM<br />
-
**[[6oik]], [[6oij]] – hTDN + AChR + antibody fragment – Cryo EM<br />
+
**[[6oik]], [[6oij]] – hTDN + AChR + scFv – Cryo EM<br />
**[[6crk]] – hTDN + scFv <br />
**[[6crk]] – hTDN + scFv <br />
-
**[[6vms]] – r/hTDN + dopamine receptor + scFv <br />
+
**[[6vms]], [[7cmu]], [[7cmv]] – r/hTDN + dopamine receptor + scFv <br />
-
**[[6ni3]] – hTDN + endolysin/adrenergic receptor + nanobody – Cryo EM<br />
+
**[[7d77]], [[7tuz]] – hTDN + adhesion GPC receptor + scFv – Cryo EM<br />
 +
**[[7ezh]] – hTDN + cholecystokinin receptor + scFv – Cryo EM<br />
 +
**[[7exd]] – hTDN + serotonin receptor + scFv – Cryo EM<br />
 +
**[[7evy]], [[7evz]], [[7ew0]], [[7ew1]], [[7ew2]], [[7ew3]], [[7ew4]], [[7ew7]] – hTDN + S1P receptor + scFv – Cryo EM<br />
 +
**[[7vkt]] – hTDN + leukotriene B4 receptor + scFv – Cryo EM<br />
 +
**[[7wvu]] – hTDN + formyl peptide receptor + scFv + formyl peptide – Cryo EM<br />
 +
**[[6omm]], [[7t6s]] – hTDN + formyl peptide receptor + scFv + agonist – Cryo EM<br />
**[[6k41]], [[6k42]] – hTDN + adrenergic receptor + scFv – Cryo EM<br />
**[[6k41]], [[6k42]] – hTDN + adrenergic receptor + scFv – Cryo EM<br />
-
**[[6wwz]] – hTDN + chemokine receptor + scFv – Cryo EM<br />
+
**[[6wwz]], [[7vl8]] – hTDN + chemokine receptor + scFv – Cryo EM<br />
 +
**[[7eb2]] – hTDN + GABA receptor + scFv – Cryo EM<br />
 +
**[[7db6]] – hTDN + melatonin receptor + scFv – Cryo EM<br />
 +
**[[7jhj]] – hTDN + BILF1 + scFv – Cryo EM<br />
 +
**[[7l1u]] – hTDN + orexin receptor + scFv – Cryo EM<br />
 +
**[[7e9h]] – hTDN + glutamate receptor + scFv – Cryo EM<br />
 +
**[[7v68]], [[7v69]] – hTDN + muscarinic acetylcholine receptor + scFv – Cryo EM<br />
**[[6wha]] – hTDN + hydroxytryptamine receptor + scFv – Cryo EM<br />
**[[6wha]] – hTDN + hydroxytryptamine receptor + scFv – Cryo EM<br />
**[[6xbk]], [[6xbj]], [[6xbl]], [[6xbm]] – hTDN + smoothened homolog + scFv – Cryo EM<br />
**[[6xbk]], [[6xbj]], [[6xbl]], [[6xbm]] – hTDN + smoothened homolog + scFv – Cryo EM<br />
-
**[[6ot0]] – hTDN + antibody + smoothened homolog – Cryo EM<br />
+
**[[3sn6]] – TDN ba (mutant) + rb (mutant) + bc + endolysine + scFv<br />
 +
 
 +
*Transducin-α+βγ ternary complex with nanobody
 +
 
 +
**[[7ept]], [[7wuq]] – hTDN + adhesion GPC receptor + nanobody – Cryo EM<br />
 +
**[[6ni3]] – hTDN + endolysin/adrenergic receptor + nanobody – Cryo EM<br />
 +
**[[7f16]] – hTDN + PTH2 receptor + nanobody – Cryo EM<br />
 +
**[[7c2e]], [[7duq]], [[7dur]], [[7e14]], [[7evm]], [[7s3i]] – hTDN + glucagon-like peptide receptor + nanobody – Cryo EM<br />
 +
**[[7evw]] – hTDN + frizzled-7 + minGas + nanobody – Cryo EM<br />
 +
**[[7dh5]] – hTDN + adrenergic receptor + nanobody – Cryo EM<br />
 +
**[[7cx2]], [[7cx3]], [[7cx4]] – hTDN + prostaglandin receptor + nanobody – Cryo EM<br />
 +
**[[7f4d]], [[7f4f]], [[7f4h]], [[7f4i]], [[7f58]] – hTDN + melanocortin receptor + nanobody – Cryo EM<br />
 +
**[[7ljd]] – hTDN + dopamine receptor + nanobody – Cryo EM<br />
 +
**[[7v9l]] – hTDN + GHRH receptor + nanobody – Cryo EM<br />
**[[6p9y]], [[6lpb]], [[6m1i]] – hTDN + PACAP + nanobody – Cryo EM<br />
**[[6p9y]], [[6lpb]], [[6m1i]] – hTDN + PACAP + nanobody – Cryo EM<br />
**[[6li3]] – hTDN + GPR52 + nanobody – Cryo EM<br />
**[[6li3]] – hTDN + GPR52 + nanobody – Cryo EM<br />
Line 73: Line 129:
**[[7c2e]] – hTDN + glucagon receptor + nanobody – Cryo EM<br />
**[[7c2e]] – hTDN + glucagon receptor + nanobody – Cryo EM<br />
**[[7d7m]] – hTDN + prostaglandin receptor + nanobody – Cryo EM<br />
**[[7d7m]] – hTDN + prostaglandin receptor + nanobody – Cryo EM<br />
-
**[[7bz2]] – h/bTDN + adrenergic receptor + nnobody – Cryo EM<br />
+
**[[7bz2]] – h/bTDN + adrenergic receptor + nanobody – Cryo EM<br />
-
**[[6cmo]] – hTDN + antibody + rhodopsin/cytochrome b562 – Cryo EM<br />
+
-
**[[3sn6]] – TDN ba (mutant) + rb (mutant) + bc + endolysine + antibody fragment<br />
+
**[[7jjo]] – bTDN + adrenergic receptor + nanobody – Cryo EM<br />
**[[7jjo]] – bTDN + adrenergic receptor + nanobody – Cryo EM<br />
-
*Transducin-α+βγ quaternary complex with antibody
+
*Transducin-α+βγ ternary complex with antibody
 +
 
 +
**[[7o7f]] – hTDN + chemokine receptor + antibody – Cryo EM<br />
 +
**[[6ot0]] – hTDN + antibody + smoothened homolog – Cryo EM<br />
 +
**[[6cmo]] – hTDN + antibody + rhodopsin/cytochrome b562 – Cryo EM<br />
 +
 
 +
 
 +
*Transducin-α+βγ quaternary complex with scFv
-
**[[6pb1]], [[6pb0]] – hTDN + CRFR-2 + urocortin + nanobody – Cryo EM<br />
 
**[[6os9]] – hTDN + NTR1 + JMV449 + scFv – Cryo EM<br />
**[[6os9]] – hTDN + NTR1 + JMV449 + scFv – Cryo EM<br />
-
**[[6niy]], [[6e3y]] – hTDN + calcitonin receptor + calcitonin + nanobody – Cryo EM<br />
 
**[[6lfm]], [[6lfo]] – hTDN + chemokine receptor + IL8 + scFv – Cryo EM<br />
**[[6lfm]], [[6lfo]] – hTDN + chemokine receptor + IL8 + scFv – Cryo EM<br />
-
**[[6omm]] – hTDN + formyl peptide receptor + peptide agonist + scFv – Cryo EM<br />
+
**[[7l1v]] – hTDN + orexin receptor + scFv + nanobody – Cryo EM<br />
 +
**[[7sbf]], [[7scg]], [[7u2l]] – hTDN + mu opioid receptor + scFv + ligand – Cryo EM<br />
 +
**[[7dfl]] – hTDN + histamin receptor + scFv + histamin – Cryo EM<br />
 +
**[[7ryc]] – hTDN + oxytocin receptor + scFv + oxytocin – Cryo EM<br />
 +
**[[7vl9]], [[7vla]] – hTDN + chemokine receptor + scFv + CCL15 – Cryo EM<br />
 +
**[[7t6b]], [[7wf7]] – hTDN + sphingosine receptor + scFv + sphingosine – Cryo EM<br />
 +
**[[7eo2]], [[7eo4]] – hTDN + sphingosine receptor + scFv + agonist – Cryo EM<br />
 +
**[[7f2o]] – hTDN + bradykinin receptor + scFv + polypeptide – Cryo EM<br />
 +
**[[7aue]] – hTDN + melatonin receptor + scFv + aminoserine – Cryo EM<br />
 +
**[[7vgy]], [[7vgz]] – hTDN + melatonin receptor + scFv + cholesterol + drug – Cryo EM<br />
 +
**[[7w53]], [[7w55]], [[7w56]], [[7w57]] – hTDN + neuromedin receptor + scFv + neuromedin – Cryo EM<br />
 +
**[[6xox]], [[7rg9]] – hTDN + glucagon-like peptide receptor + scFv + nanobody – Cryo EM<br />
 +
**[[7rgp]] – hTDN + glucagon-like peptide receptor + scFv + nanobody + polypeptide – Cryo EM<br />
 +
**[[7dw9]] – hTDN + vasopressin receptor + scFv + nanobody + polypeptide – Cryo EM<br />
 +
**[[7ezk]], [[7ezm]] – hTDN + cholecystokinin receptor + cholecystokinin + scFv – Cryo EM<br />
 +
**[[7f8w]] – hTDN + cholecystokinin receptor + gastrin + scFv – Cryo EM<br />
 +
**[[7ej0]], [[7ej8]], [[7eja]], [[7ejk]] – hTDN + adrenergic receptor + scFv + drug – Cryo EM<br />
 +
**[[7rkx]], [[7rky]] – hTDN + GPC receptor + scFv + GDP – Cryo EM<br />
 +
**[[7rkf]], [[7rkm]], [[7rkn]] – hTDN + GPC receptor + scFv + fractalkine – Cryo EM<br />
 +
**[[7ejx]], [[7vug]] – hTDN + GPC receptor + scFv + ligand – Cryo EM<br />
 +
**[[7na7]], [[7w2z]] – hTDN + ghrelin receptor + scFv + gherlin – Cryo EM<br />
 +
**[[7e9g]] – hTDN + glutamate receptor + scFv + DN13 – Cryo EM<br />
 +
**[[7p00]], [[7p02]] – hTDN + substance P receptor + scFv + substance P – Cryo EM<br />
 +
**[[7t11]] – hTDN + somatostatin receptor + scFv + octreotide – Cryo EM<br />
 +
**[[7t10]] – hTDN + somatostatin receptor + scFv + somatostatin – Cryo EM<br />
 +
**[[7s8o]] – hTDN + MAS-related receptor + scFv + ligand – Cryo EM<br />
 +
**[[7vdh]], [[7vdl]], [[7vdm]], [[7vuy]], [[7vuz]], [[7vv3]], [[7vv5]] – hTDN + MAS-related receptor + scFv + cholesterol + ligand – Cryo EM<br />
 +
**[[7s8m]] – hTDN + MAS-related receptor + scFv + cortistatin – Cryo EM<br />
 +
**[[7v6a]] – hTDN + muscarinic acetylcholine receptor + scFv + piperidine derivative – Cryo EM<br />
 +
**[[7jvr]] – hTDN + dopamine receptor + ligand + scFv – Cryo EM<br />
 +
 
 +
*Transducin-α+βγ quaternary complex with nanobody
 +
 
 +
**[[6pb1]], [[6pb0]] – hTDN + CRFR-2 + urocortin + nanobody – Cryo EM<br />
 +
**[[6niy]], [[6e3y]], [[7tyi]], [[7tyn]], [[7tyo]] – hTDN + calcitonin receptor + calcitonin + nanobody – Cryo EM<br />
 +
**[[7tyw]] – hTDN + calcitonin receptor + calcitonin + receptor activity-modifying protein + nanobody – Cryo EM<br />
**[[6vn7]] – hTDN + VIP-1 receptor + PACAP + nanobody – Cryo EM<br />
**[[6vn7]] – hTDN + VIP-1 receptor + PACAP + nanobody – Cryo EM<br />
**[[6m1h]] – hTDN + PAC1 receptor + maxadilan + nanobody – Cryo EM<br />
**[[6m1h]] – hTDN + PAC1 receptor + maxadilan + nanobody – Cryo EM<br />
Line 93: Line 187:
**[[6uva]], [[6uun]], [[6uus]] – hTDN + receptor activity-modifying protein + ADM2 + CGRP receptor + nanobody – Cryo EM<br />
**[[6uva]], [[6uun]], [[6uus]] – hTDN + receptor activity-modifying protein + ADM2 + CGRP receptor + nanobody – Cryo EM<br />
**[[6b3j]] – hTDN + GLP-1R + exendin-p5 + nanobody – Cryo EM<br />
**[[6b3j]] – hTDN + GLP-1R + exendin-p5 + nanobody – Cryo EM<br />
 +
**[[7wq3]], [[7wq4]] – hTDN + galanin receptor + nanobody + galanin – Cryo EM<br />
 +
**[[7f53]], [[7f54]], [[7f55]], [[7piu]], [[7piv]] – hTDN + melanocortin receptor + nanobody + peptide agonist – Cryo EM<br />
 +
**[[7vgx]] – hTDN + neuropeptide receptor + nanobody + neuropeptide agonist – Cryo EM<br />
 +
**[[7dty]] – hTDN + insulinotropic receptor + gastric inhibitory polypeptide + nanobody – Cryo EM<br />
 +
**[[7bb6]], [[7bb7]] – hTDN + vasopressin receptor + vasopressin + nanobody – Cryo EM<br/>
 +
**[[7ki0]], [[7ki1]], [[7d68]], [[7rtb]], [[7s1m]] – hTDN + glucagon-like peptide receptor + nanobody + glucagon derivative – Cryo EM<br />
 +
**[[7lll]] – hTDN + glucagon-like peptide receptor + nanobody + exendin – Cryo EM<br />
 +
**[[7fim]], [[7lly]], [[7v35]], [[7vbh]], [[7vbi]] – hTDN + glucagon-like peptide receptor + nanobody + polypeptide – Cryo EM<br />
 +
**[[7mbx]] – hTDN + cholecystokinin receptor + cholecystokinin + nanobody – Cryo EM<br />
 +
**[[7bz2]], [[7dhi]], [[7dhr]] – hTDN + adrenergic receptor + nanobody + agonist – Cryo EM<br />
 +
**[[7xjh]], [[7xji]] – hTDN + adrenergic receptor + nanobody + drug – Cryo EM<br />
 +
**[[7vuh]], [[7vui]], [[7vuj]] – hTDN + GPC receptor + nanobody + ligand – Cryo EM<br />
 +
**[[7f9y]], [[7f9z]], [[7na8]] – hTDN + ghrelin receptor + nanobody + pyrazole derivative – Cryo EM<br />
 +
P receptor + scFv + substance P – Cryo EM<br />
 +
**[[7rmg]], [[7rmh]], [[7rmi]] – hTDN + substance P receptor + nanobody + substance P – Cryo EM<br />
 +
**[[7v9m]] – hTDN + GHRH receptor + nanobody + somatoliberin – Cryo EM<br />
 +
**[[7tyl]] – hTDN + calcitonin receptor + nanobody + amylin peptide – Cryo EM<br />
 +
**[[7tyf]], [[7tyh]], [[7tyx]], [[7tyy]], [[7tzf]] – hTDN + calcitonin receptor + nanobody + amylin peptide + receptor activity-modifying protein - Cryo EM<br />
 +
**[[7fin]], [[7fiy]], [[7ra3]], [[7vab]] – hTDN + GIP receptor + nanobody + polypeptide – Cryo EM<br />
 +
**[[7cky]], [[7crh]], [[7jv5]], [[7jvp]], [[7jvq]] – hTDN + dopamine receptor + ligand + nanobody – Cryo EM<br />
 +
 +
*Transducin-α+βγ quaternary complex with scFv and nanobody
 +
 +
**[[7rbt]] – hTDN + GIP receptor + nanobody + scFv + polypeptide – Cryo EM<br />
 +
**[[7joz]] – hTDN + dopamine receptor + scFv + nanobody <br />
 +
**[[7wu2]], [[7wu3]], [[7wui]], [[7wuj]] – hTDN + adhesion GPC receptor + scFv + nanobody – Cryo EM<br />
 +
**[[7ckw]], [[7ckx]], [[7ckz]], [[7ljc]] – hTDN + dopamine receptor + scFv + nanobody – Cryo EM<br />
 +
**[[7kh0]] – hTDN + vasopressin receptor + vasopressin + scFv + nanobody – Cryo EM<br />
 +
 +
*Transducin-α+βγ quaternary complex with antibody
 +
**[[6qno]] – h/bTDN + antibody + rhodopsin + retinal – Cryo EM<br />
**[[6qno]] – h/bTDN + antibody + rhodopsin + retinal – Cryo EM<br />
 +
**[[6oya]] – bTDN + antibody + rhodopsin + retinal – Cryo EM<br />
 +
}}
}}
[[Category: Topic Page]]
[[Category: Topic Page]]

Revision as of 07:20, 15 May 2022

3D structures of transducin

Updated on 15-May-2022 - For a general description of the protein see Transducin


P receptor + scFv + substance P – Cryo EM

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Jaime Prilusky

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