7blv
From Proteopedia
(Difference between revisions)
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==Crystal structure of the tick-borne encephalitis virus NS3 helicase in complex with ADP== | ==Crystal structure of the tick-borne encephalitis virus NS3 helicase in complex with ADP== | ||
| - | <StructureSection load='7blv' size='340' side='right'caption='[[7blv]]' scene=''> | + | <StructureSection load='7blv' size='340' side='right'caption='[[7blv]], [[Resolution|resolution]] 2.10Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7BLV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7BLV FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[7blv]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7BLV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7BLV FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7blv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7blv OCA], [https://pdbe.org/7blv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7blv RCSB], [https://www.ebi.ac.uk/pdbsum/7blv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7blv ProSAT]</span></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr> |
| + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[7ay4|7ay4]], [[7oj4|7oj4]], [[7bm0|7bm0]], [[7nxu|7nxu]]</div></td></tr> | ||
| + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/RNA_helicase RNA helicase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.4.13 3.6.4.13] </span></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7blv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7blv OCA], [https://pdbe.org/7blv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7blv RCSB], [https://www.ebi.ac.uk/pdbsum/7blv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7blv ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[https://www.uniprot.org/uniprot/A0A2S1PWV0_9FLAV A0A2S1PWV0_9FLAV]] Functions as a signal peptide for NS4B and is required for the interferon antagonism activity of the latter.[ARBA:ARBA00003504] Serine protease subunit NS2B: Required cofactor for the serine protease function of NS3.[PROSITE-ProRule:PRU00859] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Anindita | + | [[Category: RNA helicase]] |
| - | [[Category: Franta Z]] | + | [[Category: Anindita, P D]] |
| - | [[Category: Grinkevich P]] | + | [[Category: Franta, Z]] |
| + | [[Category: Grinkevich, P]] | ||
| + | [[Category: Hydrolase]] | ||
| + | [[Category: Rna helicase]] | ||
| + | [[Category: Viral protein]] | ||
Revision as of 10:20, 18 May 2022
Crystal structure of the tick-borne encephalitis virus NS3 helicase in complex with ADP
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