3p0l
From Proteopedia
(Difference between revisions)
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==Human steroidogenic acute regulatory protein== | ==Human steroidogenic acute regulatory protein== | ||
- | <StructureSection load='3p0l' size='340' side='right' caption='[[3p0l]], [[Resolution|resolution]] 3.40Å' scene=''> | + | <StructureSection load='3p0l' size='340' side='right'caption='[[3p0l]], [[Resolution|resolution]] 3.40Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
- | <table><tr><td colspan='2'>[[3p0l]] is a 4 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[3p0l]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3P0L OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3P0L FirstGlance]. <br> |
- | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">STAR, STARD1 ([ | + | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">STAR, STARD1 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> |
- | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3p0l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3p0l OCA], [https://pdbe.org/3p0l PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3p0l RCSB], [https://www.ebi.ac.uk/pdbsum/3p0l PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3p0l ProSAT]</span></td></tr> |
</table> | </table> | ||
== Disease == | == Disease == | ||
- | [[ | + | [[https://www.uniprot.org/uniprot/STAR_HUMAN STAR_HUMAN]] Non-classic congenital lipoid adrenal hyperplasia due to STAR deficency;Classic congenital lipoid adrenal hyperplasia due to STAR deficency;Familial glucocorticoid deficiency. The disease is caused by mutations affecting the gene represented in this entry. |
== Function == | == Function == | ||
- | [[ | + | [[https://www.uniprot.org/uniprot/STAR_HUMAN STAR_HUMAN]] Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone. |
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Human]] | [[Category: Human]] | ||
+ | [[Category: Large Structures]] | ||
[[Category: Arrowsmith, C H]] | [[Category: Arrowsmith, C H]] | ||
[[Category: Berg, S Van Den]] | [[Category: Berg, S Van Den]] |
Revision as of 11:06, 18 May 2022
Human steroidogenic acute regulatory protein
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Categories: Human | Large Structures | Arrowsmith, C H | Berg, S Van Den | Berglund, H | Busam, R D | Collins, R | Dahlgren, L G | Edwards, A M | Flodin, S | Flores, A | Graslund, S | Hallberg, B M | Hammarstrom, M | Herman, M D | Johansson, A | Johansson, I | Kallas, A | Karlberg, T | Kotenyova, T | Lehtio, L | Moche, M | Nilsson, M E | Nordlund, P | Nyman, T | Persson, C | Structural genomic | Sagemark, J | Schuler, H | Siponen, M | Sundstrom, M | Svensson, L | Thorsell, A G | Tresaugues, L | Weigelt, J | Welin, M | Cholesterol | Cholesterol transport | Mitochondria | Sgc | Start domain | Transport protein