Art:Dodecapod

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[[Image:7sya-rainbow-trace-C.png]]
[[Image:7sya-rainbow-trace-C.png]]
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<br>'''<font color="blue">N</font>[[Image:Arrow.gif]]<font color="red">C</font>''' Rainbow, C-face.
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[[Image:7sya-rainbow-N.png]]
[[Image:7sya-rainbow-N.png]]
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<br>'''<font color="blue">N</font>[[Image:Arrow.gif]]<font color="red">C</font>''' Rainbow, N-face.
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[[Image:7sya-rainbow-C.png]]
[[Image:7sya-rainbow-C.png]]
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<br>'''<font color="blue">N</font>[[Image:Arrow.gif]]<font color="red">C</font>''' Rainbow, C-face.
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[[Image:7sya-dist-N.png]]<br>Distance from center, C-face
[[Image:7sya-dist-N.png]]<br>Distance from center, C-face

Revision as of 17:27, 23 May 2022

Image:7sya-rainbow.gif

Tailed bacteriophages and herpesviruses have a DNA "pipe" in their capsids, called a portal protein[1]. The images here depict 7sya, a homo-dodecamer[1]. In the animation at right, each of the 12 protein chains is colored amino to carboxy spectrum (N->C Rainbow):

N               C

All images show a model simplified to alpha carbons only. Except for the top row, the alpha carbons are rendered at an exaggerated diameter (6.0 Å) to give a solid appearance. All images and the animation were generated with FirstGlance in Jmol (version 4.0, not yet released in mid-May 2022), most using color schemes available under Solid (Views tab). The two faces of the oblate structure (or tube with a flange) are designated the N-face (face with amino termini) and the C-face (face with carboxy termini).

Image:7sya-rainbow-trace-N.png
NImage:Arrow.gifC Rainbow, N-face.

Image:7sya-rainbow-trace-C.png
NImage:Arrow.gifC Rainbow, C-face.

Image:7sya-rainbow-N.png
NImage:Arrow.gifC Rainbow, N-face.

Image:7sya-rainbow-C.png
NImage:Arrow.gifC Rainbow, C-face.

Image:7sya-dist-N.png
Distance from center, C-face

Image:7sya-seq-N.png
12 sequence-identical chains, C-face

Image:7sya-ss-N.png
2° structure, N-face

Image:7sya-ss-C.png
2° structure, C-face

Image:7sya-ch-N.png
Chains are distinct colors, N-face

Image:7sya-ch-C.png
Chains are distinct colors, C-face

Image:7sya-gs-N.png
Distance from center, N-face

Image:7sya-gs-C.png
Distance from center, C-face


References & Notes

  1. ↑ 1.0 1.1 David Hou CF, Swanson NA, Li F, Yang R, Lokareddy RK, Cingolani G. Cryo-EM Structure of a Kinetically Trapped Dodecameric Portal Protein from the Pseudomonas-phage PaP3. J Mol Biol. 2022 Mar 9;434(9):167537. doi: 10.1016/j.jmb.2022.167537. PMID:35278476 doi:http://dx.doi.org/10.1016/j.jmb.2022.167537

Proteopedia Page Contributors and Editors (what is this?)

Eric Martz

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