3p97
From Proteopedia
(Difference between revisions)
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==Dengue 3 NS5 Methyltransferase bound to the substrate S-Adenosyl methionine== | ==Dengue 3 NS5 Methyltransferase bound to the substrate S-Adenosyl methionine== | ||
- | <StructureSection load='3p97' size='340' side='right' caption='[[3p97]], [[Resolution|resolution]] 1.70Å' scene=''> | + | <StructureSection load='3p97' size='340' side='right'caption='[[3p97]], [[Resolution|resolution]] 1.70Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
- | <table><tr><td colspan='2'>[[3p97]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[3p97]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Dengue_virus_3 Dengue virus 3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3P97 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3P97 FirstGlance]. <br> |
- | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SAM:S-ADENOSYLMETHIONINE'>SAM</scene></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SAM:S-ADENOSYLMETHIONINE'>SAM</scene></td></tr> |
- | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3p8z|3p8z]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3p8z|3p8z]]</div></td></tr> |
- | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3p97 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3p97 OCA], [https://pdbe.org/3p97 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3p97 RCSB], [https://www.ebi.ac.uk/pdbsum/3p97 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3p97 ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
- | [[ | + | [[https://www.uniprot.org/uniprot/C1KBQ3_9FLAV C1KBQ3_9FLAV]] Envelope protein E binding to host cell surface receptor is followed by virus internalization through clathrin-mediated endocytosis. Envelope protein E is subsequently involved in membrane fusion between virion and host late endosomes. Synthesized as a homodimer with prM which acts as a chaperone for envelope protein E. After cleavage of prM, envelope protein E dissociate from small envelope protein M and homodimerizes (By similarity).[SAAS:SAAS026470_004_099774] |
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Dengue virus 3]] | [[Category: Dengue virus 3]] | ||
+ | [[Category: Large Structures]] | ||
[[Category: Lescar, J]] | [[Category: Lescar, J]] | ||
[[Category: Noble, C G]] | [[Category: Noble, C G]] |
Revision as of 08:29, 25 May 2022
Dengue 3 NS5 Methyltransferase bound to the substrate S-Adenosyl methionine
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