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3paq

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==Surfactant Protein A neck and carbohydrate recognition domain (NCRD) complexed with alpha-methylmannose==
==Surfactant Protein A neck and carbohydrate recognition domain (NCRD) complexed with alpha-methylmannose==
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<StructureSection load='3paq' size='340' side='right' caption='[[3paq]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
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<StructureSection load='3paq' size='340' side='right'caption='[[3paq]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3paq]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Buffalo_rat Buffalo rat]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PAQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3PAQ FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3paq]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Buffalo_rat Buffalo rat]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PAQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3PAQ FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MMA:O1-METHYL-MANNOSE'>MMA</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MMA:O1-METHYL-MANNOSE'>MMA</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1r13|1r13]], [[1r14|1r14]], [[3pak|3pak]], [[3pbf|3pbf]], [[3par|3par]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1r13|1r13]], [[1r14|1r14]], [[3pak|3pak]], [[3pbf|3pbf]], [[3par|3par]]</div></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Sftpa1, Sftp-1, Sftp1, Sftpa ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10116 Buffalo rat])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Sftpa1, Sftp-1, Sftp1, Sftpa ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10116 Buffalo rat])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3paq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3paq OCA], [http://pdbe.org/3paq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3paq RCSB], [http://www.ebi.ac.uk/pdbsum/3paq PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3paq ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3paq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3paq OCA], [https://pdbe.org/3paq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3paq RCSB], [https://www.ebi.ac.uk/pdbsum/3paq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3paq ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/SFTPA_RAT SFTPA_RAT]] In presence of calcium ions, it binds to surfactant phospholipids and contributes to lower the surface tension at the air-liquid interface in the alveoli of the mammalian lung and is essential for normal respiration.
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[[https://www.uniprot.org/uniprot/SFTPA_RAT SFTPA_RAT]] In presence of calcium ions, it binds to surfactant phospholipids and contributes to lower the surface tension at the air-liquid interface in the alveoli of the mammalian lung and is essential for normal respiration.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</StructureSection>
</StructureSection>
[[Category: Buffalo rat]]
[[Category: Buffalo rat]]
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[[Category: Large Structures]]
[[Category: Cafarella, T M]]
[[Category: Cafarella, T M]]
[[Category: Head, J]]
[[Category: Head, J]]

Revision as of 08:31, 25 May 2022

Surfactant Protein A neck and carbohydrate recognition domain (NCRD) complexed with alpha-methylmannose

PDB ID 3paq

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