3pit

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==Crystal structure of M-RasD41E in complex with GppNHp (type 2)==
==Crystal structure of M-RasD41E in complex with GppNHp (type 2)==
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<StructureSection load='3pit' size='340' side='right' caption='[[3pit]], [[Resolution|resolution]] 1.55&Aring;' scene=''>
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<StructureSection load='3pit' size='340' side='right'caption='[[3pit]], [[Resolution|resolution]] 1.55&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3pit]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PIT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3PIT FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3pit]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PIT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3PIT FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GNP:PHOSPHOAMINOPHOSPHONIC+ACID-GUANYLATE+ESTER'>GNP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GNP:PHOSPHOAMINOPHOSPHONIC+ACID-GUANYLATE+ESTER'>GNP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1x1s|1x1s]], [[3kkp|3kkp]], [[3kko|3kko]], [[3kkm|3kkm]], [[3pir|3pir]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1x1s|1x1s]], [[3kkp|3kkp]], [[3kko|3kko]], [[3kkm|3kkm]], [[3pir|3pir]]</div></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Mras, Xras ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Mras, Xras ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3pit FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3pit OCA], [http://pdbe.org/3pit PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3pit RCSB], [http://www.ebi.ac.uk/pdbsum/3pit PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3pit ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3pit FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3pit OCA], [https://pdbe.org/3pit PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3pit RCSB], [https://www.ebi.ac.uk/pdbsum/3pit PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3pit ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/RASM_MOUSE RASM_MOUSE]] May serve as an important signal transducer for a novel upstream stimuli in controlling cell proliferation. Weakly activates the MAP kinase pathway (By similarity).
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[[https://www.uniprot.org/uniprot/RASM_MOUSE RASM_MOUSE]] May serve as an important signal transducer for a novel upstream stimuli in controlling cell proliferation. Weakly activates the MAP kinase pathway (By similarity).
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Large Structures]]
[[Category: Lk3 transgenic mice]]
[[Category: Lk3 transgenic mice]]
[[Category: Hirai, R]]
[[Category: Hirai, R]]

Revision as of 08:41, 25 May 2022

Crystal structure of M-RasD41E in complex with GppNHp (type 2)

PDB ID 3pit

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