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3pso
From Proteopedia
(Difference between revisions)
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==Crystal structure of mouse VPS29 complexed with Zn2+== | ==Crystal structure of mouse VPS29 complexed with Zn2+== | ||
| - | <StructureSection load='3pso' size='340' side='right' caption='[[3pso]], [[Resolution|resolution]] 3.20Å' scene=''> | + | <StructureSection load='3pso' size='340' side='right'caption='[[3pso]], [[Resolution|resolution]] 3.20Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3pso]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[3pso]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3lh6 3lh6]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PSO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3PSO FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> |
| - | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2r17|2r17]], [[1w24|1w24]], [[1x2x|1x2x]], [[1z2w|1z2w]], [[3psn|3psn]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2r17|2r17]], [[1w24|1w24]], [[1x2x|1x2x]], [[1z2w|1z2w]], [[3psn|3psn]]</div></td></tr> |
| - | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Vps29 ([ | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Vps29 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3pso FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3pso OCA], [https://pdbe.org/3pso PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3pso RCSB], [https://www.ebi.ac.uk/pdbsum/3pso PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3pso ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/VPS29_MOUSE VPS29_MOUSE]] Essential component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network. Also required to regulate transcytosis of the polymeric immunoglobulin receptor (pIgR-pIgA). Has low protein phosphatase activity towards a serine-phosphorylated peptide derived from IGF2R (in vitro) (By similarity). Has no activity towards p-nitrophenylphosphate, p-nitrophenylphosphorylcholine or phosphatidylinositlphosphates (in vitro). |
| + | |||
| + | ==See Also== | ||
| + | *[[Vacuolar protein sorting-associated protein 3D structures|Vacuolar protein sorting-associated protein 3D structures]] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
[[Category: Lk3 transgenic mice]] | [[Category: Lk3 transgenic mice]] | ||
[[Category: Chhabra, S]] | [[Category: Chhabra, S]] | ||
Revision as of 08:53, 25 May 2022
Crystal structure of mouse VPS29 complexed with Zn2+
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Categories: Large Structures | Lk3 transgenic mice | Chhabra, S | Collins, B | Ghai, R | Norwood, S | Shaw, D | Swarbrick, J | Valkov, E | Hydrolase | Membrane trafficking | Phosphatase fold | Scaffold | Snx1 | Tbc1d5 | Vps35
