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3q0m
From Proteopedia
(Difference between revisions)
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==Crystal structure of the PUMILIO-homology domain from Human PUMILIO1 in complex with p38alpha NREb== | ==Crystal structure of the PUMILIO-homology domain from Human PUMILIO1 in complex with p38alpha NREb== | ||
| - | <StructureSection load='3q0m' size='340' side='right' caption='[[3q0m]], [[Resolution|resolution]] 2.71Å' scene=''> | + | <StructureSection load='3q0m' size='340' side='right'caption='[[3q0m]], [[Resolution|resolution]] 2.71Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3q0m]] is a 4 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[3q0m]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q0M OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3Q0M FirstGlance]. <br> |
| - | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3q0l|3q0l]], [[3q0n|3q0n]], [[3q0o|3q0o]], [[3q0p|3q0p]], [[3q0q|3q0q]], [[3q0r|3q0r]], [[3q0s|3q0s]]</td></tr> | + | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3q0l|3q0l]], [[3q0n|3q0n]], [[3q0o|3q0o]], [[3q0p|3q0p]], [[3q0q|3q0q]], [[3q0r|3q0r]], [[3q0s|3q0s]]</div></td></tr> |
| - | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PUM1, KIAA0099, PUMH1 ([ | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PUM1, KIAA0099, PUMH1 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3q0m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3q0m OCA], [https://pdbe.org/3q0m PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3q0m RCSB], [https://www.ebi.ac.uk/pdbsum/3q0m PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3q0m ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/PUM1_HUMAN PUM1_HUMAN]] Sequence-specific RNA-binding protein that regulates translation and mRNA stability by binding the 3'-UTR of mRNA targets. May be required to support proliferation and self-renewal of stem cells (By similarity). |
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Human]] | [[Category: Human]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Hall, T M.T]] | [[Category: Hall, T M.T]] | ||
[[Category: Lu, G]] | [[Category: Lu, G]] | ||
Revision as of 09:04, 25 May 2022
Crystal structure of the PUMILIO-homology domain from Human PUMILIO1 in complex with p38alpha NREb
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