3q2f
From Proteopedia
(Difference between revisions)
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==Crystal Structure of the bromodomain of human BAZ2B in complex with a triazolo ligand== | ==Crystal Structure of the bromodomain of human BAZ2B in complex with a triazolo ligand== | ||
| - | <StructureSection load='3q2f' size='340' side='right' caption='[[3q2f]], [[Resolution|resolution]] 2.06Å' scene=''> | + | <StructureSection load='3q2f' size='340' side='right'caption='[[3q2f]], [[Resolution|resolution]] 2.06Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3q2f]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[3q2f]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q2F OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3Q2F FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=OAM:4-{4-[3-(1H-IMIDAZOL-1-YL)PROPYL]-5-METHYL-4H-1,2,4-TRIAZOL-3-YL}-1-METHYL-1H-PYRAZOL-5-AMINE'>OAM</scene></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=OAM:4-{4-[3-(1H-IMIDAZOL-1-YL)PROPYL]-5-METHYL-4H-1,2,4-TRIAZOL-3-YL}-1-METHYL-1H-PYRAZOL-5-AMINE'>OAM</scene></td></tr> |
| - | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3g0l|3g0l]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3g0l|3g0l]]</div></td></tr> |
| - | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">BAZ2B, KIAA1476 ([ | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">BAZ2B, KIAA1476 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3q2f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3q2f OCA], [https://pdbe.org/3q2f PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3q2f RCSB], [https://www.ebi.ac.uk/pdbsum/3q2f PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3q2f ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/BAZ2B_HUMAN BAZ2B_HUMAN]] May play a role in transcriptional regulation interacting with ISWI. |
| + | |||
| + | ==See Also== | ||
| + | *[[Bromodomain adjacent to zinc finger 3D structures|Bromodomain adjacent to zinc finger 3D structures]] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Human]] | [[Category: Human]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Arrowsmith, C H]] | [[Category: Arrowsmith, C H]] | ||
[[Category: Bountra, C]] | [[Category: Bountra, C]] | ||
Revision as of 05:48, 8 June 2022
Crystal Structure of the bromodomain of human BAZ2B in complex with a triazolo ligand
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Categories: Human | Large Structures | Arrowsmith, C H | Bountra, C | Delft, F von | Edwards, A M | Felletar, I | Filippakopoulos, P | Keates, T | Knapp, S | Muniz, J R.C | Picaud, S | Structural genomic | Weigelt, J | Bazb2 | Bromodomain adjacent to zinc finger domain | Kiaa1476 | Sgc | Transcription | Walp4
