This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
3q30
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
==Human Squalene synthase in complex with (2R,3R)-2-Carboxymethoxy-3-[5-(2-naphthalenyl)pentyl]aminocarbonyl-3-[5-(2-naphthalenyl)pentyloxy]propionic acid== | ==Human Squalene synthase in complex with (2R,3R)-2-Carboxymethoxy-3-[5-(2-naphthalenyl)pentyl]aminocarbonyl-3-[5-(2-naphthalenyl)pentyloxy]propionic acid== | ||
| - | <StructureSection load='3q30' size='340' side='right' caption='[[3q30]], [[Resolution|resolution]] 2.00Å' scene=''> | + | <StructureSection load='3q30' size='340' side='right'caption='[[3q30]], [[Resolution|resolution]] 2.00Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3q30]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[3q30]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q30 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3Q30 FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=D61:(2R,3R)-2-(CARBOXYMETHOXY)-4-{[5-(NAPHTHALEN-2-YL)PENTYL]AMINO}-3-{[5-(NAPHTHALEN-2-YL)PENTYL]OXY}-4-OXOBUTANOIC+ACID'>D61</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=D61:(2R,3R)-2-(CARBOXYMETHOXY)-4-{[5-(NAPHTHALEN-2-YL)PENTYL]AMINO}-3-{[5-(NAPHTHALEN-2-YL)PENTYL]OXY}-4-OXOBUTANOIC+ACID'>D61</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> |
| - | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3q2z|3q2z]], [[3asx|3asx]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3q2z|3q2z]], [[3asx|3asx]]</div></td></tr> |
| - | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">FDFT1 ([ | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">FDFT1 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> |
| - | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Squalene_synthase Squalene synthase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.21 2.5.1.21] </span></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3q30 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3q30 OCA], [https://pdbe.org/3q30 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3q30 RCSB], [https://www.ebi.ac.uk/pdbsum/3q30 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3q30 ProSAT]</span></td></tr> |
</table> | </table> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
| Line 19: | Line 19: | ||
</div> | </div> | ||
<div class="pdbe-citations 3q30" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 3q30" style="background-color:#fffaf0;"></div> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Squalene synthase|Squalene synthase]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
| Line 24: | Line 27: | ||
</StructureSection> | </StructureSection> | ||
[[Category: Human]] | [[Category: Human]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Squalene synthase]] | [[Category: Squalene synthase]] | ||
[[Category: Higashihashi, N]] | [[Category: Higashihashi, N]] | ||
Revision as of 05:49, 8 June 2022
Human Squalene synthase in complex with (2R,3R)-2-Carboxymethoxy-3-[5-(2-naphthalenyl)pentyl]aminocarbonyl-3-[5-(2-naphthalenyl)pentyloxy]propionic acid
| |||||||||||
Categories: Human | Large Structures | Squalene synthase | Higashihashi, N | Ichikawa, M | Itoh, M | Katakura, S | Shimizu, H | Sugita, K | Suzuki, M | Usui, H | Yamazaki, K | Yokomizo, A | Isoprene biosynthesis | Lipid synthesis | Multifunctional enzyme | Oxidoreductase | Steroid biosynthesis | Sterol biosynthesis | Transferase-transferase inhibitor complex
