3q3s
From Proteopedia
(Difference between revisions)
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==EthR from Mycobacterium tuberculosis in complex with compound BDM5683== | ==EthR from Mycobacterium tuberculosis in complex with compound BDM5683== | ||
| - | <StructureSection load='3q3s' size='340' side='right' caption='[[3q3s]], [[Resolution|resolution]] 2.00Å' scene=''> | + | <StructureSection load='3q3s' size='340' side='right'caption='[[3q3s]], [[Resolution|resolution]] 2.00Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3q3s]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[3q3s]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_tuberculosis"_(zopf_1883)_klein_1884 "bacillus tuberculosis" (zopf 1883) klein 1884]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q3S OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3Q3S FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=O8B:2-(2-METHYLPHENOXY)-N-[2-(4-METHYLPHENYL)-2H-BENZOTRIAZOL-5-YL]ACETAMIDE'>O8B</scene></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=O8B:2-(2-METHYLPHENOXY)-N-[2-(4-METHYLPHENYL)-2H-BENZOTRIAZOL-5-YL]ACETAMIDE'>O8B</scene></td></tr> |
| - | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1u9n|1u9n]], [[3o8g|3o8g]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1u9n|1u9n]], [[3o8g|3o8g]]</div></td></tr> |
| - | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ethR, etaR, MT3970, Rv3855 ([ | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ethR, etaR, MT3970, Rv3855 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1773 "Bacillus tuberculosis" (Zopf 1883) Klein 1884])</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3q3s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3q3s OCA], [https://pdbe.org/3q3s PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3q3s RCSB], [https://www.ebi.ac.uk/pdbsum/3q3s PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3q3s ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/ETHR_MYCTU ETHR_MYCTU]] Involved in the repression of the monooxygenase EthA which is responsible of the formation of the active metabolite of ethionamide (ETH).<ref>PMID:10869356</ref> <ref>PMID:10944230</ref> |
| + | |||
| + | ==See Also== | ||
| + | *[[Tetracycline repressor protein 3D structures|Tetracycline repressor protein 3D structures]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
[[Category: Lens, Z]] | [[Category: Lens, Z]] | ||
[[Category: Villeret, V]] | [[Category: Villeret, V]] | ||
Revision as of 05:50, 8 June 2022
EthR from Mycobacterium tuberculosis in complex with compound BDM5683
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