3qhy
From Proteopedia
(Difference between revisions)
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==Structural, thermodynamic and kinetic analysis of the picomolar binding affinity interaction of the beta-lactamase inhibitor protein-II (BLIP-II) with class A beta-lactamases== | ==Structural, thermodynamic and kinetic analysis of the picomolar binding affinity interaction of the beta-lactamase inhibitor protein-II (BLIP-II) with class A beta-lactamases== | ||
- | <StructureSection load='3qhy' size='340' side='right' caption='[[3qhy]], [[Resolution|resolution]] 2.06Å' scene=''> | + | <StructureSection load='3qhy' size='340' side='right'caption='[[3qhy]], [[Resolution|resolution]] 2.06Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
- | <table><tr><td colspan='2'>[[3qhy]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[3qhy]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/"actinomyces_exfoliatus"_waksman_and_curtis_1916 "actinomyces exfoliatus" waksman and curtis 1916] and [https://en.wikipedia.org/wiki/"bacillus_cereus_var._anthracis"_(cohn_1872)_smith_et_al._1946 "bacillus cereus var. anthracis" (cohn 1872) smith et al. 1946]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QHY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3QHY FirstGlance]. <br> |
- | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1jtd|1jtd]], [[1jtg|1jtg]], [[3qi0|3qi0]]</td></tr> | + | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1jtd|1jtd]], [[1jtg|1jtg]], [[3qi0|3qi0]]</div></td></tr> |
- | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">bla1, BA_2507, GBAA2507, GBAA_2507 ([ | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">bla1, BA_2507, GBAA2507, GBAA_2507 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1392 "Bacillus cereus var. anthracis" (Cohn 1872) Smith et al. 1946]), bliB ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1905 "Actinomyces exfoliatus" Waksman and Curtis 1916])</td></tr> |
- | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] </span></td></tr> |
- | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3qhy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qhy OCA], [https://pdbe.org/3qhy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3qhy RCSB], [https://www.ebi.ac.uk/pdbsum/3qhy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3qhy ProSAT]</span></td></tr> |
</table> | </table> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
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==See Also== | ==See Also== | ||
- | *[[Beta-lactamase|Beta-lactamase]] | + | *[[Beta-lactamase 3D structures|Beta-lactamase 3D structures]] |
*[[TEM1-beta-Lactamase/beta-lactamase Inhibitor Protein (BLIP)|TEM1-beta-Lactamase/beta-lactamase Inhibitor Protein (BLIP)]] | *[[TEM1-beta-Lactamase/beta-lactamase Inhibitor Protein (BLIP)|TEM1-beta-Lactamase/beta-lactamase Inhibitor Protein (BLIP)]] | ||
== References == | == References == | ||
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[[Category: Actinomyces exfoliatus waksman and curtis 1916]] | [[Category: Actinomyces exfoliatus waksman and curtis 1916]] | ||
[[Category: Beta-lactamase]] | [[Category: Beta-lactamase]] | ||
+ | [[Category: Large Structures]] | ||
[[Category: Structural genomic]] | [[Category: Structural genomic]] | ||
[[Category: Brown, N G]] | [[Category: Brown, N G]] |
Revision as of 06:09, 8 June 2022
Structural, thermodynamic and kinetic analysis of the picomolar binding affinity interaction of the beta-lactamase inhibitor protein-II (BLIP-II) with class A beta-lactamases
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Categories: Actinomyces exfoliatus waksman and curtis 1916 | Beta-lactamase | Large Structures | Structural genomic | Brown, N G | Chow, D C | Palzkill, T | Prasad, B V.V | Sankaran, B | Zwart, P | Beta-propeller | Enyzme-inhibitor complex | Hydrolase-hydrolase inhibitor complex | Protein:protein interaction