3qmd
From Proteopedia
(Difference between revisions)
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==Structural Basis of Selective Binding of Nonmethylated CpG Islands by the CXXC Domain of CFP1== | ==Structural Basis of Selective Binding of Nonmethylated CpG Islands by the CXXC Domain of CFP1== | ||
| - | <StructureSection load='3qmd' size='340' side='right' caption='[[3qmd]], [[Resolution|resolution]] 1.90Å' scene=''> | + | <StructureSection load='3qmd' size='340' side='right'caption='[[3qmd]], [[Resolution|resolution]] 1.90Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3qmd]] is a 3 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[3qmd]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QMD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3QMD FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> |
| - | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3qmb|3qmb]], [[3qmc|3qmc]], [[3qmg|3qmg]], [[3qmh|3qmh]], [[3qmi|3qmi]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3qmb|3qmb]], [[3qmc|3qmc]], [[3qmg|3qmg]], [[3qmh|3qmh]], [[3qmi|3qmi]]</div></td></tr> |
| - | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CXXC1 ([ | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CXXC1 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3qmd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qmd OCA], [https://pdbe.org/3qmd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3qmd RCSB], [https://www.ebi.ac.uk/pdbsum/3qmd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3qmd ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/CXXC1_HUMAN CXXC1_HUMAN]] Transcriptional activator that exhibits a unique DNA binding specificity for CpG unmethylated motifs with a preference for CpGG.<ref>PMID:21407193</ref> |
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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</div> | </div> | ||
<div class="pdbe-citations 3qmd" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 3qmd" style="background-color:#fffaf0;"></div> | ||
| - | |||
| - | ==See Also== | ||
| - | *[[User:Wayne Decatur/UNH BCHEM833 Structural Analysis Workshop Session Fall 2012|User:Wayne Decatur/UNH BCHEM833 Structural Analysis Workshop Session Fall 2012]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Human]] | [[Category: Human]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Arrowsmith, C H]] | [[Category: Arrowsmith, C H]] | ||
[[Category: Bian, C B]] | [[Category: Bian, C B]] | ||
Revision as of 06:14, 8 June 2022
Structural Basis of Selective Binding of Nonmethylated CpG Islands by the CXXC Domain of CFP1
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