Tubulin 3D Structures

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**[[5n5n]] – hTUBA-1A+hTUB-3 + GTP + GMPCPP – Cryo EM<br />
**[[5n5n]] – hTUBA-1A+hTUB-3 + GTP + GMPCPP – Cryo EM<br />
**[[6e7b]] – hTUBA-1B+hTUB-3 + GTP + GMPCPP – Cryo EM<br />
**[[6e7b]] – hTUBA-1B+hTUB-3 + GTP + GMPCPP – Cryo EM<br />
-
**[[5ij0]] – hTUBA-1B+hTUB-3 + GTP + GDP – Cryo EM<br />
+
**[[7sja]] – hTUBA-1B+hTUB-3 + GTP – Cryo EM<br />
 +
**[[7sj9]] – hTUBA-1B+hTUB-3 + microtubule-associated protein + GTP – Cryo EM<br />
 +
**[[5ij0]], [[7sj7]], [[7sj8]] – hTUBA-1B+hTUB-3 + GTP + GDP – Cryo EM<br />
**[[5ij9]] – hTUBA-1B+hTUB-3 (mutant) + GTP + GDP – Cryo EM<br />
**[[5ij9]] – hTUBA-1B+hTUB-3 (mutant) + GTP + GDP – Cryo EM<br />
**[5n5n]] – hTUBA-1B+hTUB-5 + GTP + GMPCPP – Cryo EM<br />
**[5n5n]] – hTUBA-1B+hTUB-5 + GTP + GMPCPP – Cryo EM<br />
**[6e7c]] – hTUBA-1B+hTUB-2B + GTP + GMPCPP – Cryo EM<br />
**[6e7c]] – hTUBA-1B+hTUB-2B + GTP + GMPCPP – Cryo EM<br />
**[[6i2i]] – hTUBA-1B +hTUB-5 + GTP + GMPCPP + stabilizer – Cryo EM<br />
**[[6i2i]] – hTUBA-1B +hTUB-5 + GTP + GMPCPP + stabilizer – Cryo EM<br />
 +
**[[7lxb]], [[7m18]], [[7m20]] - hTUBA+hTUBB + GDP + GTP + drug – Cryo EM<br />
 +
**[[7pjf]] - hTUBA+hTUBB + darpin + GTP <br />
**[[1jff]] - bTUBA+bTUBB - bovine<br />
**[[1jff]] - bTUBA+bTUBB - bovine<br />
**[[6wvr]], [[6wvl]], [[6wvm]] - bTUBA+ bTUBB +GTP + GDP + stabilizer - Cryo EM<br />
**[[6wvr]], [[6wvl]], [[6wvm]] - bTUBA+ bTUBB +GTP + GDP + stabilizer - Cryo EM<br />
**[[3j6f]] - pTUBA+pTUBB – pig - Cryo EM <br />
**[[3j6f]] - pTUBA+pTUBB – pig - Cryo EM <br />
-
**[[3j6e]], [[6evw]] - pTUBA+pTUBB +GMPCPP – Cryo EM <br />
+
**[[3j6e]], [[7dmz]] - pTUBA+pTUBB +GMPCPP – Cryo EM <br />
-
**[[6dpu]] - pTUBA+pTUBB + GMPCPP + GTP – Cryo EM <br />
+
**[[3j7i]] - pTUBA+pTUBB +GTP – Cryo EM<br />
-
**[[3j7i]] - pTUBA+pTUBB + GTP – Cryo EM<br />
+
**[[7sgs]] - pTUBA+pTUBB + esconsin + GTP – Cryo EM<br />
-
**[[6o2r]], [[6o2q]], [[6o2s]], [[6o2t]], [[5xxw]], [[5xxv]], [[5xxt]] - pTUBA+pTUBB +GTP + GDP – Cryo EM<br />
+
**[[6o2r]], [[6o2q]], [[6o2s]], [[6o2t]], [[5xxw]], [[5xxv]], [[5xxt]], [[6evx]], [[6evz]], [[6ew0]], [[6dpv]] - pTUBA+pTUBB +GTP + GDP – Cryo EM<br />
-
**[[5xxx]] - pTUBA+pTUBB +GTP + GMPCPP – Cryo EM<br />
+
**[[6evy]], [[6dpw]] - pTUBA+pTUBB + GTPgS + GTP – Cryo EM<br />
-
**[[6evx]], [[6evy]], [[6evz]], [[6ew0]], [[6dpu]], [[6dpv]], [[6dpw]] - pTUBA+pTUBB + GTP + GDP - Cryo EM<br />
+
**[[5xxx]], [[7dn0]] - pTUBA+pTUBB +GTP + GMPCPP – Cryo EM<br />
 +
**[[6dpu]], [[6evw]] - pTUBA+pTUBB + GMPCPP + GTP – Cryo EM <br />
**[[1tub]] - pTUBA+pTUBB – electron diffraction<br />
**[[1tub]] - pTUBA+pTUBB – electron diffraction<br />
-
**[[5w3h]] - yTUBA+ yTUBB +GTP + GDP – yeast - Cryo EM<br />
+
**[[5w3f]], [[5w3j]] - yTUBA+ yTUBB +GTP + GDP – yeast - Cryo EM<br />
 +
**[[5w3h]] - yTUBA+ yTUBB +GTP + GDP + stabilizer - Cryo EM<br />
**[[2btq]] – PdTUBA+PdTUBB<br />
**[[2btq]] – PdTUBA+PdTUBB<br />
-
**[[5w3f]] - yTUBA+yTUBB + GDP + GTP - yeast<br />
+
**[[6e88]] - TUBA+ TUBB +GTP + GDP – Caenorhabditis elegans - Cryo EM<br />
-
**[[5w3j]] - yTUBA+yTUBB (mutant) + GDP + GTP + stabilizer<br />
+
**[[6ve7]], [[6u42]] – TUBA + TUBB + GTP + GDP + stabilizer – Chlamydomonas reinhardtii - Cryo EM<br />
-
**[[5ubq]], [[5ucy]] - TUBA+ TUBB – ''Tetrahymena thermophila'' - Cryo EM <br />
+
**[[6u0h]], [[5ubq]], [[5ucy]] - TtTUBA+TUBB + GTP + GDP – Tetrahymena thermophila - Cryo EM<br />
-
**[[6e88]] - TUBA+ TUBB +GTP + GDP – ''Caenorhabditis elegans'' - Cryo EM<br />
+
**[[7miz]] - TUBA+TUBB + SPM1 + PDI + GTP + GDP – Toxoplasma gondii - Cryo EM<br />
-
**[[6ve7]], [[6u42]] – TUBA + TUBB + GTP + GDP + stabilizer – ''Chlamydomonas reinhardtii'' - Cryo EM<br />
+
-
*α-tubulin + β-tubulin complexes with stathmin-4
+
*α-tubulin + β-tubulin complexes with stathmin
 +
**[[5lp6]] – bTUBA1B +bTUBB2B +stathmin-4 + protein<br />
**[[3du7]], [[3e22]], [[1z2b]], [[1sa0]], [[1sa1]], [[1ffx]] – bTUBA1C+bTUBB2B+stathmin-4<br />
**[[3du7]], [[3e22]], [[1z2b]], [[1sa0]], [[1sa1]], [[1ffx]] – bTUBA1C+bTUBB2B+stathmin-4<br />
-
**[[5lp6]] – bTUBA1B +bTUBB2B +stathmin-4 + protein<br />
+
**[[5la6]] - bTUBA+bTUBB+stathmin-4 + protein + GDP + GTP + ATP derivative + benzodioxol derivative<br />
-
**[[5la6]], [[5m7e]], [[5bmv]], [[5lov]], [[5lxt]], [[5lxj]], [[5m7e]], [[5m7g]], [[5m8d]], [[5m8g]], [[5mf4]], [[5ov7]], [[5lxs]], [[5xlt]], [[5o7a]], [[5xlt]] - bTUBA+bTUBB+stathmin-4 + protein + GDP + GTP + ATP derivative + inhibitor<br />
+
**[[7jfr]] - bTUBA+bTUBB+stathmin-4 + protein + GDP + GTP + ATP derivative + auristatin<br />
-
**[[5njh]] - bTUBA+bTUBB+stathmin-4 + protein + GDP + GTP + ATP derivative + triazolopyrimidine<br />
+
**[[6xes]], [[6xet]], [[7lz7]], [[7lz8]] – pTUBA1B +pTUBB +stathmin-4 + inhibitor<br />
-
**[[6n47]] - pTUBA+ pTUBB+stathmin-4 + protein + GDP + GTP + ATP derivative + pyrimidine derivative<br />
+
-
**[[5jcb]], [[5ca0]], [[5yl2]], [[5ylj]], [[5yls]] - pTUBA+ pTUBB+stathmin-4 + protein + GDP + GTP + ATP derivative + depolymerizer<br />
+
-
**[[5ezy]] - pTUBA+ bTUBB+stathmin-4 + protein + GDP + GTP + ATP derivative + stabilizer<br />
+
**[[3hkb]], [[3hkc]], [[3hkd]], [[3hke]], [[3n2g]], [[3n2k]], [[3ryc]], [[3ryf]], [[3ryh]], [[3ryi]], [[4eb6]] – sTUBA+sTUBB+stathmin-4 – sheep<br />
**[[3hkb]], [[3hkc]], [[3hkd]], [[3hke]], [[3n2g]], [[3n2k]], [[3ryc]], [[3ryf]], [[3ryh]], [[3ryi]], [[4eb6]] – sTUBA+sTUBB+stathmin-4 – sheep<br />
**[[4f61]] - sTUBA+sTUBB+stathmin-like protein R4<br />
**[[4f61]] - sTUBA+sTUBB+stathmin-like protein R4<br />
**[[3ut5]] - sTUBA+sTUBB+stathmin-4 + vinca peptide<br />
**[[3ut5]] - sTUBA+sTUBB+stathmin-4 + vinca peptide<br />
**[[4eb6]] - sTUBA+sTUBB+stathmin-4<br />
**[[4eb6]] - sTUBA+sTUBB+stathmin-4<br />
-
**[[4f6r]] - sTUBA+sTUBB+stathmin-like protein R1 + ankyrin repeat protein<br />
+
4f6r - sTUBA+sTUBB+stathmin-like protein R1 + ankyrin repeat
 +
protein
**[[6tde]] - sTUBA+sTUBB+stathmin-4 + GDP + GTP<br />
**[[6tde]] - sTUBA+sTUBB+stathmin-4 + GDP + GTP<br />
**[[6h9b]] - sTUBA+sTUBB+stathmin-4 + GDP + GTP + quinoline derivative<br />
**[[6h9b]] - sTUBA+sTUBB+stathmin-4 + GDP + GTP + quinoline derivative<br />
-
**[[6u0h]], [[5ubq]], [[5ucy]] - TtTUBA+TUBB + GTP + GDP – ''Tetrahymena thermophila'' - Cryo EM<br />
 
-
*α-tubulin + β-tubulin complexes with stathmin-4 and tubulin-tyrosine ligase (TTL)
+
*α-tubulin + β-tubulin complexes with stathmin and tubulin Tyr-ligase
-
**[[4iij]] - bTUBA+bTUBB+stathmin-4 + TTL<br />
+
**[[4o2a]], [[4iij]], [[4i55]] - bTUBA+bTUBB+stathmin-4 + TUB-Tyr ligase<br />
-
**[[4o2a]] - bTUBA+bTUBB+stathmin-4 + TTL + GDP + GTP + ADP + drug<br />
+
**[[4wbn]], [[6s9e]], [[6gze]], [[6i5c]] - bTUBA+bTUBB+stathmin-4 + TUB-Tyr ligase + GDP + GTP + ATP derivative<br />
-
**[[4ihj]] - bTUBA+bTUBB+stathmin-4 + TTL + ADP<br />
+
-
**[[6i5c]], [[4i55]], [[6s9e]], [[6gze]] - bTUBA+bTUBB+stathmin-4 + TTL + GDP + GTP + ATP derivative<br />
+
-
**[[6qqn]], [[6knz]] - bTUBA+bTUBB+stathmin-4 + TUB-Tyr ligase + GDP + GTP + ATP derivative + pyrimidine derivative<br />
+
**[[5xlz]] - bTUBA+bTUBB+stathmin-4 + TUB-Tyr ligase + GDP + GTP + ATP derivative + anthracene derivative<br />
**[[5xlz]] - bTUBA+bTUBB+stathmin-4 + TUB-Tyr ligase + GDP + GTP + ATP derivative + anthracene derivative<br />
-
**[[6hx8]], [[6gj4]], [[6y6d]] - bTUBA1B+bTUBB2B+stathmin-4 + TTL + GDP + GTP + ATP derivative + quinoline derivative<br />
+
**[[6qqn]], [[6knz]] - bTUBA+bTUBB+stathmin-4 + TUB-Tyr ligase + GDP + GTP + ATP derivative + pyrimidine derivative<br />
-
**[[6ses]] – bTUBA1B+bTUBB2B+stathmin-4 + TTL + GDP + GTP + ATP derivative + drug<br />
+
**[[6hx8]], [[6gj4]], [[6y6d]] – bTUBA1B+bTUBB2B+stathmin-4 + TUB-Tyr ligase + GDP + GTP + ATP derivative + quinoline derivative<br />
-
**[[6k9v]], [[6jcj]], [[6fkl]], [[6fkj]], [[6f7c]], [[5z4p]], [[5yz3]], [[5nfz]], [[5lyj]] – bTUBA + bTUBB + stathmin-4 + TTL + GDP + GTP + ATP derivative + inhibitor<br />
+
**[[6ses]], [[7au5]], [[7ogn]] – bTUBA1B+bTUBB2B+stathmin-4 + TUB-Tyr ligase + GDP + GTP + ATP derivative + drug<br />
-
**[[5ng1]] – bTUBA + bTUBB + stathmin-4 + TTL + GDP + GTP + ATP derivative + inhibitor + stabilizer<br />
+
**[[6k9v]], [[6jcj]], [[6fkl]], [[6fkj]], [[6f7c]], [[5z4p]], [[5yz3]], [[5nfz]], [[5lyj]], [[6y4m]], [[6y4n]], [[7cbz]], [[7cpd]], [[7cpq]], [[7e4p]], [[7e4q]], [[7e4r]], [[7e4y]], [[7e4z]] – bTUBA + bTUBB + stathmin-4 + TUB-Tyr ligase + GDP + GTP + ATP derivative + inhibitor<br />
-
**[[6fjf]], [[4tv8]] - bTUBA+bTUBB+stathmin-4 + TTL + GDP + GTP + ATP derivative + fcmaytansine<br />
+
**[[5ng1]] – bTUBA + bTUBB + stathmin-4 + TUB-Tyr ligase + GDP + GTP + ATP derivative + inhibitor + stabilizer<br />
-
**[[6fii]], [[6fjm]], [[6gf3]], [[6qtn]], [[5jh7]], [[5bmv]], [[5la6]], [[5osk]], [[5jvd]], [[5gon]], [[5xlt]], [[5xaf]], [[5xag]] – bTUBA + bTUBB +stathmin-4 + TTL + GDP + GTP + ATP derivative + anti-tumor agent<br />
+
**[[6fjf]], [[4tv8]] - bTUBA+bTUBB+stathmin-4 + TUB-Tyr ligase + GDP + GTP + ATP derivative + maytansine<br />
-
**[[5iyz]], [[5j2t]], [[5j2u]], [[4tv9]], [[4yj2]], [[4yj3]], [[2xrp]], [[7jfr]] – bTUBAB1 +bTUBBB2 +stathmin-4 + TTL + GDP + GTP + ATP derivative + auristatin anti-mitotics<br />
+
**[[4tuy]], [[4o4h]], [[4o4i]], [[4o4j]], [[4o4l]], [[4i50]], [[4i4t]],
-
**[[4o2b]] - bTUBA+bTUBB+stathmin-4 + TTL + drug<br />
+
[[6fii]], [[6fjm]], [[6gf3]], [[6qtn]], [[5jh7]], [[5bmv]], [[5la6]], [[5osk]], [[5jvd]], [[5gon]], [[5xlt]], [[5xaf]], [[5xag]] – bTUBA + bTUBB +stathmin-4 + TUB-Tyr ligase + GDP + GTP + ATP derivative + drug<br />
-
**[[4x1i]], [[4x1k]], [[4x1y]], [[4x20]], [[5eyp]] - sTUBA+bTUBB+stathmin-4 + TTL + GDP + GTP + drug<br />
+
**[[5iyz]], [[5j2t]], [[5j2u]], [[4tv9]], [[4yj2]], [[4yj3]], [[2xrp]], [[7jfr]] – bTUBAB1 +bTUBBB2 +stathmin-4 + TUB-Tyr ligase + GDP + GTP + ATP derivative + auristatin anti-mitotics<br />
-
**[[5kx5]] - sTUBA+sTUBB+stathmin-4 + TTL + GDP + GTP + ADP + inhibitor<br />
+
**[[4o2b]] - bTUBA+bTUBB+stathmin-4 + TUB-Tyr ligase + colchicine<br />
-
**[[5xp3]] – pTUBAB1 +pTUBBB2 +stathmin-4 + TTL + GDP + GTP + ATP derivative <br />
+
**[[4ihj]] - bTUBA+bTUBB+stathmin-4 + tubulin Tyr-ligase + ADP<br />
-
**[[4tuy]], [[4o4h]], [[4o4i]], [[4o4j]], [[4o4l]], [[4i50]], [[4i4t]], [[4zhq]], [[4zi7]], [[4zol]] – pTUBAB1 +pTUBBB2 +stathmin-4 + TTL + GDP + GTP + ATP derivative + fungicide<br />
+
**[[7en3]] - bTUBA+bTUBB+stathmin-4 + TUB-Tyr ligase + GDP + GTP + toxin<br />
-
**[[6d88]], [[6br1]], [[6brf]], [[6bry]], [[6bs2]], [[5yl2]], [[5ylj]], [[5yls]], [[5xhc]], [[5xi5]], [[5xi7]] – pTUBAB1 +pTUBBB2 +stathmin-4 + TTL + GDP + GTP + ATP derivative + inhibitor<br />
+
**[[4x1i]], [[4x1k]], [[4x1y]], [[4x20]] - sTUBA+bTUBB+stathmin-4 + TUB-Tyr ligase + GDP + GTP + dolastatin + colchicine<br />
-
**[[5xiw]], [[5xke]], [[5xkf]], [[5xkg]], [[5xkh]] – pTUBAB1 +pTUBBB2 +stathmin-4 + TTL + GDP + GTP + drug<br />
+
**[[5eyp]] - sTUBA+sTUBB+stathmin-4 + TUB-Tyr ligase + GDP + GTP + colchicine<br />
-
**[[5yl4]] – pTUBAB1 +pTUBBB2 +stathmin-4 + TTL + GDP + GTP + ATP derivative + drug<br />
+
**[[4zhq]], [[4zi7]], [[4zol]] – pTUBAB1 +pTUBBB2 +stathmin-4 + TUB-Tyr ligase + GDP + GTP + ATP derivative + valinamide derivative<br />
-
**[[6o5n]] - pTUBA+pTUBB+stathmin-4 + TTL + GDP + GTP + imidazole derivative<br />
+
**[[6o5n]] - pTUBA+pTUBB+stathmin-4 + TUB-Tyr ligase + GDP + GTP + i<br />
-
**[[5jqg]], [[5xp3]] - pTUBA+pTUBB+stathmin-4 + TTL + GDP + GTP + ATP derivative<br />
+
**[[6x1e]], [[6x1e]], [[6x1f]], [[7cld]], [[7cnm]], [[7cnn]], [[7dad]], [[7dae]], [[7daf]], [[7dp8]], [[7emj]] - pTUBA+pTUBB+stathmin-4 + TUB-Tyr ligase + GDP + GTP + drug<br />
-
**[[6o61]], [[6o5m]] - pTUBA+pTUBB+stathmin-4 + TTL + GDP + GTP + ATP derivative + imidazole derivative<br />
+
**[[7cno]], [[7l05]] - pTUBA+pTUBB+stathmin-4 + TUB-Tyr ligase + GDP + GTP + toxin<br />
-
**[[6nng]], [[6eg5]] - pTUBA+ pTUBB+stathmin-4 + TTL + GDP + GTP + ATP derivative + pyrimidine derivative<br />
+
**[[5jqg]], [[5xp3]] - pTUBA+pTUBB+stathmin-4 + TUB-Tyr ligase + GDP + GTP + ATP derivative<br />
-
**[[5cb4]], [[5xhc]], [[5xi5]], [[5xi7]] – pTUBA + pTUBB + stathmin-4 + TTL + GDP + GTP + ATP derivative + inhibitor<br />
+
**[[6o61]], [[6o5m]] - pTUBA+pTUBB+stathmin-4 + TUB-Tyr ligase + GDP + GTP + ATP derivative + imidazole derivative<br />
-
**[[6kpp]] – pTUBA1B + pTUBB + stathmin-4 + TTL + GDP + GTP + benzofuran derivative <br />
+
**[[6nng]], [[6eg5]] - pTUBA+ pTUBB+stathmin-4 + TUB-Tyr ligase + GDP + GTP + ATP derivative + pyrimidine derivative<br />
-
**[[5xiw]] – pTUBA + pTUBB +stathmin-4 + TTL + GDP + GTP + anti-gout agent<br />
+
**[[6n47]] - pTUBA+ pTUBB+stathmin-4 + protein + GDP + GTP + ATP derivative + pyrimidine derivative<br />
-
**[[6pc4]], [[5xkg]], [[5xkh]], [[5xke]], [[5xkf]] – pTUBA + pTUBB +stathmin-4 + TTL + GDP + GTP + anti-tumor agent<br />
+
**[[5jcb]], [[5ca0]], [[5yl2]], [[5ylj]], [[5yls]] - pTUBA+ pTUBB+stathmin-4 + protein + GDP + GTP + ATP derivative + depolymerizer<br />
-
**[[5c8y]], [[6d88]], [[6br1]], [[6brf]], [[6bry]], [[6bs2]], [[5yl4]] – pTUBA + pTUBB +stathmin-4 + TTL + GDP + GTP + ATP derivative + anti-tumor agent<br />
+
**[[5cb4]], [[5xhc]], [[5xi5]], [[5xi7]], [[7cda]], [[7ce6]], [[7ce8]], [[7cek]], [[7db9]], [[7dba]]. [[7dbb]], [[7dbc]]. [[7dbd]], [[7exc]] – pTUBA + pTUBB + stathmin-4 + TUB-Tyr ligase + GDP + GTP + ATP derivative + inhibitor<br />
-
**[[5zxh]] - pTUBA+ bTUBB (mutant) +stathmin-4 + TTL + GDP + GTP + ATP derivative + imidazole derivative<br />
+
**[[6kpp]] – pTUBA1B + pTUBB + stathmin-4 + TUB-Tyr ligase + GDP + GTP + benzofuran derivative <br />
-
**[[5z4u]], [[6agk]], [[5h7o]], [[5h74]] – pTUBA + bTUBB + stathmin-4 + TTL + GDP + GTP + ATP derivative + inhibitor<br />
+
**[[5xiw]] – pTUBA + pTUBB +stathmin-4 + TUB-Tyr ligase + GDP + GTP + anti-gout agent<br />
-
**[[5fnv]] – cTUBA + rTUBB +stathmin-4 + TTL + GDP + GTP + ATP derivative + anti-tumor agent - chicken<br />
+
**[[6pc4]], [[5xkg]], [[5xkh]], [[5xke]], [[5xkf]] – pTUBA + pTUBB +stathmin-4 + TUB-Tyr ligase + GDP + GTP + anti-tumor agent<br />
-
**[[5ca1]] – pTUBA + cTUBB + stathmin-4 + TTL + GDP + GTP + ATP derivative + inhibitor<br />
+
**[[5c8y]], [[6d88]], [[6br1]], [[6brf]], [[6bry]], [[6bs2]], [[5yl4]] – pTUBA + pTUBB +stathmin-4 + TUB-Tyr ligase + GDP + GTP + ATP derivative + anti-tumor agent<br />
 +
**[[5ezy]] - pTUBA+ bTUBB+stathmin-4 + protein + GDP + GTP + ATP derivative + stabilizer<br />
 +
**[[5zxh]] - pTUBA+ bTUBB (mutant) +stathmin-4 + TUB-Tyr ligase + GDP + GTP + ATP derivative + imidazole derivative<br />
 +
**[[5z4u]], [[6agk]], [[5h7o]], [[5h74]] – pTUBA + bTUBB + stathmin-4 + TUB-Tyr ligase + GDP + GTP + ATP derivative + inhibitor<br />
 +
**[[5fnv]] – cTUBA + rTUBB +stathmin-4 + TUB-Tyr ligase + GDP + GTP + ATP derivative + anti-tumor agent - chicken<br />
 +
**[[5ca1]] – pTUBA + cTUBB + stathmin-4 + TUB-Tyr ligase + GDP + GTP + ATP derivative + inhibitor<br />
*α-tubulin + β-tubulin complex with kinesin
*α-tubulin + β-tubulin complex with kinesin
Line 98: Line 103:
**[[2wbe]] – bTUBA1D+bTUBB2B+kinesin+AMPPNP <br />
**[[2wbe]] – bTUBA1D+bTUBB2B+kinesin+AMPPNP <br />
**[[3dco]] - bTUBA+bTUBB+kinesin-like NOD<br />
**[[3dco]] - bTUBA+bTUBB+kinesin-like NOD<br />
-
**[[4ck5]], [[4ck6]], [[4ck7]] - bTUBA+bTUBB+kinesin-like KIF11 motor domain<br />
+
**[4ck5]], [[4ck6]], [[4ck7]] - bTUBA+bTUBB+kinesin-like KIF11 motor domain<br />
-
**[[5mio]] - bTUBA+bTUBB+kinesin-like KIF2C motor domain<br />
+
**[[5hnw]], [[5hnx]], [[5hny]], [[5hnz]] – bTUBAB1 +bTUBBB2 +kinesin-14 + GDP + GTP + stabilizer<br />
**[[5hnw]], [[5hnx]], [[5hny]], [[5hnz]] – bTUBAB1 +bTUBBB2 +kinesin-14 + GDP + GTP + stabilizer<br />
-
**[[3edl]] - bTUBA1D+bTUBB2B+kinesin motor domain<br />
+
**[[3edl}} - bTUBA1D+bTUBB2B+kinesin motor domain<br />
**[[4hna]] - bTUBA+bTUBB + kinesin heavy chain + ankyrin repeat protein<br />
**[[4hna]] - bTUBA+bTUBB + kinesin heavy chain + ankyrin repeat protein<br />
**[[4uxo]], [[4uxp]], [[4uxr]], [[4uxs]], [[4uxy]] - bTUBA+bTUBB + kinesin motor domain + GDP + GTP + stabilizer – Cryo EM<br />
**[[4uxo]], [[4uxp]], [[4uxr]], [[4uxs]], [[4uxy]] - bTUBA+bTUBB + kinesin motor domain + GDP + GTP + stabilizer – Cryo EM<br />
**[[4uxt]], [[4uy0]] - bTUBA+bTUBB + kinesin heavy chain + GDP + GTP + stabilizer – Cryo EM<br />
**[[4uxt]], [[4uy0]] - bTUBA+bTUBB + kinesin heavy chain + GDP + GTP + stabilizer – Cryo EM<br />
 +
**[[3j2u]] - bTUBA+bTUBB+kinesin-like KLP10A head domain<br />
**[[3j2u]] - bTUBA+bTUBB+kinesin-like KLP10A head domain<br />
**[[4aqv]], [[4aqw ]]- bTUBA+bTUBB+kinesin-like KIF11 – Cryo EM<br />
**[[4aqv]], [[4aqw ]]- bTUBA+bTUBB+kinesin-like KIF11 – Cryo EM<br />
-
**[[5nd3]] - bTUBA+bTUBB+kinesin-like KIF20A + GDP + GTP – Cryo EM<br />
 
-
**[[5nd2]], [[5nd4]] - bTUBA+bTUBB+kinesin-like KIF20A + GDP + GTP + ADP – Cryo EM<br />
 
-
**[[5nd7]] - bTUBA+bTUBB+kinesin-like KIF20A + AMPPNP – Cryo EM<br />
 
-
**[[6bbn]] - bTUBA+bTUBB+kinesin-like KIF2A + DARPIN + AMPPNP + GDP + GTP<br />
 
**[[4atx]] - bTUBA1D+bTUBB2B+kinesin motor domain – Cryo EM<br />
**[[4atx]] - bTUBA1D+bTUBB2B+kinesin motor domain – Cryo EM<br />
 +
**[[6zpi]] - bTUBA1D+bTUBB2B+kinesin motor domain Kif15 – Cryo EM<br />
**[[5mm7]] - bTUBA1A+bTUBB +kinesin-4 motor domain + GTP + GDP + ANP + stabilizer – Cryo EM<br />
**[[5mm7]] - bTUBA1A+bTUBB +kinesin-4 motor domain + GTP + GDP + ANP + stabilizer – Cryo EM<br />
**[[5mm4]] - bTUBA1A+bTUBB +kinesin-5 motor domain + GTP + GDP + ANP + stabilizer – Cryo EM<br />
**[[5mm4]] - bTUBA1A+bTUBB +kinesin-5 motor domain + GTP + GDP + ANP + stabilizer – Cryo EM<br />
**[[5ogc]], [[5oam]] - bTUBA+pTUBB+kinesin-like KIF18A + GTP + GDP + stabilizer – Cryo EM<br />
**[[5ogc]], [[5oam]] - bTUBA+pTUBB+kinesin-like KIF18A + GTP + GDP + stabilizer – Cryo EM<br />
**[[5ocu]] - bTUBA+pTUBB+kinesin-like KIF18A + GTP + GDP + ANP + stabilizer – Cryo EM<br />
**[[5ocu]] - bTUBA+pTUBB+kinesin-like KIF18A + GTP + GDP + ANP + stabilizer – Cryo EM<br />
-
**[[5m5i]], [[5m5l]], [[5m5m]], [[5m5n]], [[5m5o]] - bTUBA1D+bTUBB2B+kinesin-5 motor domain + AMPPNP – Cryo EM<br />
+
**[[2hxf]] - pTUBA+pTUBB+kinesin-like KIF1A+AMPPNP <br />
-
**[[2hxf]], [[6b0c]] - pTUBA+pTUBB+kinesin-like KIF1A+AMPPNP - Cryo EM<br />
+
**[[6bbn]] - pTUBA+pTUBB+kinesin-like KIF2A + darpin + ANP + GDP + GTP<br />
**[[6bbn]] - pTUBA+pTUBB+kinesin-like KIF2A + darpin + ANP + GDP + GTP<br />
**[[3j6h]] - pTUBA+pTUBB +GMPCPP + kinesin heavy chain – Cryo EM <br />
**[[3j6h]] - pTUBA+pTUBB +GMPCPP + kinesin heavy chain – Cryo EM <br />
Line 130: Line 131:
**[[6vpp]] - pTUBA+pTUBB+kinesin-like KLP61F + GTP + GDP – Cryo EM<br />
**[[6vpp]] - pTUBA+pTUBB+kinesin-like KLP61F + GTP + GDP – Cryo EM<br />
**[[6vpo]] - pTUBA+pTUBB+kinesin-like KLP61F + GTP + GDP + ANP – Cryo EM<br />
**[[6vpo]] - pTUBA+pTUBB+kinesin-like KLP61F + GTP + GDP + ANP – Cryo EM<br />
 +
**[[7nb8]] - pTUBA+pTUBB+kinesin-5 motor domain + GTP + G2P – Cryo EM<br />
 +
**[[7nba]] - pTUBA+pTUBB+kinesin-5 motor domain + GTP + G2P + ANP – Cryo EM<br />
**[[6mlr]] - pTUBA+pTUBB+kinesin-like KIF7 + GTP + GDP + ANP + stabilizer – Cryo EM<br />
**[[6mlr]] - pTUBA+pTUBB+kinesin-like KIF7 + GTP + GDP + ANP + stabilizer – Cryo EM<br />
**[[6mlq]] - pTUBA+pTUBB+kinesin-like KIF7 + GTP + GDP + ADP + stabilizer – Cryo EM<br />
**[[6mlq]] - pTUBA+pTUBB+kinesin-like KIF7 + GTP + GDP + ADP + stabilizer – Cryo EM<br />
 +
**[[7lvr]] - pTUBA+pTUBB+kinesin-like KIF14 + GTP + GDP + ADP – Cryo EM<br />
 +
**[[6wwe]], [[6wwf]], [[6wwg]], [[6wwh]], [[6wwi]], [[6wwj]], [[6wwk]], [[6wwl]], [[6wwm]], [[6wwn]], [[6wwo]], [[6wvp]], [[6wwq]], [[6wwr]], [[6wws]], [[6wwu]], [[6wwv]], [[7lvq]] - pTUBA+pTUBB+kinesin-like KIF14 + GTP + GDP + ANP – Cryo EM<br />
**[[6s8m]] - pTUBA+pTUBB+kinesin-like CUT7 + GTP + GDP + ANP – Cryo EM<br />
**[[6s8m]] - pTUBA+pTUBB+kinesin-like CUT7 + GTP + GDP + ANP – Cryo EM<br />
-
**[[6boi]] - pTUBA+pTUBB + kinesin-like KLP10A + GDP + GTP + stabilizer – Cryo EM<br />
 
-
**[[6b0l]] - pTUBA+pTUBB + kinesin-like KLP10A + GDP + GTP + AMPPNP + stabilizer – Cryo EM<br />
 
**[[4lnu]] - sTUBA+sTUBB + ankyrin repeat protein + GDP + GTP + kinesin heavy chain <br />
**[[4lnu]] - sTUBA+sTUBB + ankyrin repeat protein + GDP + GTP + kinesin heavy chain <br />
**[[5mlv]] - fyTUBA+ fyTUBB+kinesin-like CUT7 + GTP + GDP + ANP – fission yeast - Cryo EM<br />
**[[5mlv]] - fyTUBA+ fyTUBB+kinesin-like CUT7 + GTP + GDP + ANP – fission yeast - Cryo EM<br />
-
**[[6u0h]] - TtTUBA+TUBB + GTP + GDP – ''Tetrahymena thermophila'' - Cryo EM<br />
+
 
-
**[[6u0u]], [[6u0t]] - TtTUBA+TUBB+ profilament ribbon protein + GTP + GDP - Cryo EM<br />
+
-
**[[5o09]] - PdTUBA+TUBB +GDP + GTP + kinesin light chain - Cryo EM <br />
+
*α-tubulin + β-tubulin other complexes
*α-tubulin + β-tubulin other complexes
Line 149: Line 150:
**[[6quy]] - hTUBA+hTUBB +GTP + GDP + stabilizer + CKK – Cryo EM<br />
**[[6quy]] - hTUBA+hTUBB +GTP + GDP + stabilizer + CKK – Cryo EM<br />
**[[6wsl]] - hTUBA1A+hTUBB3 + small vasohibin-binding protein + tubulinyl-Tyr carboxypeptidase + GMPCPP + GTP – Cryo EM<br />
**[[6wsl]] - hTUBA1A+hTUBB3 + small vasohibin-binding protein + tubulinyl-Tyr carboxypeptidase + GMPCPP + GTP – Cryo EM<br />
-
**[[1tvk]] - bTUBA+bTUBB+GDP+GTP+Epothilone A – electron crystallography<br />
+
**[[7nvnl]] – hTUB2A in TRIC coplex + nanobody – Cryo EM<br />
 +
**[[6zwb]], [[6zwc]], [[7z01]], [[7z02]] - bTUBA+bTUBB + darpin + photoswitch + GTP + GDP<br />
 +
**[[7alr]], [[7odn]] - bTUBA+bTUBB + darpin + drug + GTP + GDP<br />
 +
**[[7z7d]] - bTUBA+bTUBB+GDP+GTP+ drug <br />
 +
**[[1tvk]] - bTUBA+bTUBB+GDP+GTP+ drug – electron crystallography<br />
**[[3iz0]] - bTUBA+bTUBB+hNDC80/SPC25+hNUF2/SPC24 – electron microscopy<br />
**[[3iz0]] - bTUBA+bTUBB+hNDC80/SPC25+hNUF2/SPC24 – electron microscopy<br />
**[[3j1t]], [[3j1u]] - bTUBA+bTUBB+ dynein<br />
**[[3j1t]], [[3j1u]] - bTUBA+bTUBB+ dynein<br />
Line 156: Line 161:
**[[5itz]] - bTUBA+bTUBB + CENP-J + darpin + GTP + GDP + colchicine <br />
**[[5itz]] - bTUBA+bTUBB + CENP-J + darpin + GTP + GDP + colchicine <br />
**[[5eib]] - bTUBA+bTUBB + CENP-J peptide + darpin + GTP + GDP<br />
**[[5eib]] - bTUBA+bTUBB + CENP-J peptide + darpin + GTP + GDP<br />
-
**[[6kiq]], [[6kio]] - pTUBA1A+pTUBB + dynein heavy chain – Cryo EM<br />
+
**[[7ac5]] - bTUBA+ bTUBB + stathmin-like domain R1 + darpin + GDP + GTP <br />
-
**[[5nqu]], [[5nqt]] - bTUBA+bTUBB + ankyrin repeat protein + GDP + GTP<br />
+
**[[6kiq]], [[6kio]] – pTUBA1A+pTUBB + dynein heavy chain – Cryo EM<br />
-
**[[5nm5]] - bTUBA+bTUBB + ankyrin repeat protein + GDP + GTP + colchicine<br />
+
-
**[[5m50]], [[5m54]], [[5m5c]] - bTUBA+bTUBB + calmodulin-regulated spectrin-associated protein + GDP + GTP - Cryo EM<br />
+
**[[3j6p]], [[6rzb]] - pTUBA+pTUBB +GTP + GDP + stabilizer + dynein heavy chain – Cryo EM<br />
**[[3j6p]], [[6rzb]] - pTUBA+pTUBB +GTP + GDP + stabilizer + dynein heavy chain – Cryo EM<br />
-
**[[3j6g]] - pTUBA+pTUBB +GTP + GDP + taxol – Cryo EM <br />
+
**[[3j6g]] - pTUBA+pTUBB +GTP + GDP + stabilizer – Cryo EM <br />
-
**[[6cvj]], [[6cvn]] - pTUBA+pTUBB + GTP + GDP + tau protein – Cryo EM <br />
+
**[[5kmg]] - pTUBA+pTUBB + protein regulator + GTP + GDP – Cryo EM <br />
**[[5kmg]] - pTUBA+pTUBB + protein regulator + GTP + GDP – Cryo EM <br />
-
**[[6cvj]], [[6cvn]] – pTUBA1B+pTUBB + tau + GTP + GDP – Cryo EM <br />
+
**[[6cvj]], [[6cvn], [[7pqc]], [[7pqp]] – pTUBA1B+pTUBB + tau + GTP + GDP – Cryo EM <br />
-
**[[6mzg]], [[6mzf]], [[6mze]] - pTUBA+pTUBB + STU2P + darpin + GTP + GDP <br />
+
**[[6mzg]], [[6mzf]], [[6mze]] - pTUBA+pTUBB + STU2P + darpin + GTP + GDP <br />
**[[5syg]], [[5syf]], [[5sye]], [[5syc]] - pTUBA+pTUBB + STU2P + stabilizer + GTP + GDP <br />
**[[5syg]], [[5syf]], [[5sye]], [[5syc]] - pTUBA+pTUBB + STU2P + stabilizer + GTP + GDP <br />
**[[6gx7]] - sTUBA+sTUBB + alpharep + low calcium response + GTP<br />
**[[6gx7]] - sTUBA+sTUBB + alpharep + low calcium response + GTP<br />
**[[6gwd]], [[6gwc]] - sTUBA+sTUBB + alpharep + GTP + GDP<br />
**[[6gwd]], [[6gwc]] - sTUBA+sTUBB + alpharep + GTP + GDP<br />
-
**[[6bjc]], [[6gvn]] - pTUBA+pTUBB + targeting protein for Xklp2 + GTP + GMPCPP – Cryo EM <br />
+
**[[7q1e]], [[7q1f]], [[7z0f]], [[7z0g]] - sTUBA+sTUBB + alpharep + CENP-J + GTP + GDP<br />
 +
**[[6bjc]], [[6gvn]] - sTUBA+sTUBB + darpin + GTP <br />
**[[6gvm]] - sTUBA+sTUBB + stathmin-like domain R1 + darpin + GDP + GTP <br />
**[[6gvm]] - sTUBA+sTUBB + stathmin-like domain R1 + darpin + GDP + GTP <br />
-
**[[4abo]] - pTUBA+pTUBB+ microtubule integrity protein MAL3<br />
 
**[[4drx]] - sTUBA+sTUBB + ankyrin repeat protein<br />
**[[4drx]] - sTUBA+sTUBB + ankyrin repeat protein<br />
**[[4ffb]], [[4u3j]] - yTUBA+TUBB (mutant) + protein STU2 <br />
**[[4ffb]], [[4u3j]] - yTUBA+TUBB (mutant) + protein STU2 <br />
**[[5mjs]] - fyTUBA+ fyTUBB + MAL3 + GTP + GDP + ANP - Cryo EM<br />
**[[5mjs]] - fyTUBA+ fyTUBB + MAL3 + GTP + GDP + ANP - Cryo EM<br />
**[[6u0u]], [[6u0t]] - TtTUBA+TUBB+ profilament ribbon protein + GTP + GDP - Cryo EM<br />
**[[6u0u]], [[6u0t]] - TtTUBA+TUBB+ profilament ribbon protein + GTP + GDP - Cryo EM<br />
 +
**[[7mwg]] - TtTUBA+TUBB + GTP + GDP - Cryo EM<br />
 +
**[[7pje]] - TtTUBA+TtTUBB + darpin + GTP <br />
 +
**[[7n32]] - TtTUBA+TtTUBB + dynein + GTP + GDP – Cryo EM<br />
-
*γ-tubulin
+
γ-tubulin
-
**[[6v5v]] – hTUBG1 + GDP – Cryo EM<br />
+
**[[6v5v]], [[7qj0]], [[7qj1]], [[7qj2]], [[7qj3]], [[7qj4]], [[7qj5]], [[7qj6]], [[7qj7]], [[7qj8]], [[7qj9]], [[7qja]], [[7qjb]], [[7qjc]], [[7qjd]] – hTUBG1 + GDP – Cryo EM<br />
-
**[[3cb2]] – hTUBG1+GDP<br />
+
**[[7qje]] – hTUBG1 + TUBG components 4,5,6 – Cryo EM<br />
-
**[[1z5v]] - hTUBG1+GTPgS<br />
+
3cb2 – hTUBG1+GDP
-
**[[1z5w]] - hTUBG1+GTP<br />
+
1z5v - hTUBG1+GTPgS
 +
1z5w - hTUBG1+GTP
**[[6v6b]] – hTUBG2 + TUBG3 – Cryo EM<br />
**[[6v6b]] – hTUBG2 + TUBG3 – Cryo EM<br />
**[[6x0v]] – hTUBG2 + mitotic-spindle organizing protein + Cep215 – Cryo EM<br />
**[[6x0v]] – hTUBG2 + mitotic-spindle organizing protein + Cep215 – Cryo EM<br />
-
**[[3rip]] – hTUBG4<br />
+
[[3rip]] – hTUBG4<br />
**[[6v69]] – hTUBG4 + TUBG5 – Cryo EM<br />
**[[6v69]] – hTUBG4 + TUBG5 – Cryo EM<br />
**[[6x0u]] – hTUBG3 + TUBG6 + mitotic spindle organizing protein – Cryo EM<br />
**[[6x0u]] – hTUBG3 + TUBG6 + mitotic spindle organizing protein – Cryo EM<br />
Line 192: Line 198:
**[[6v6s]] – hTUBG + ADP + GDP – Cryo EM<br />
**[[6v6s]] – hTUBG + ADP + GDP – Cryo EM<br />
**[[6tf9]] – TUBG – frog - Cryo EM<br />
**[[6tf9]] – TUBG – frog - Cryo EM<br />
 +
**[[7m2w]], [[7m2x]], [[7m2y]], [[7m2z]] – yTUBG + SPC97 + SPC98 - Cryo EM<br />
**[[6l80]] – fyTUBG subunit Mod21 + mitotic-spindle organizing protein<br />
**[[6l80]] – fyTUBG subunit Mod21 + mitotic-spindle organizing protein<br />
-
**[[7anz]] – TUBG – ''Candida albicans'' - Cryo EM<br />
+
**[[7anz]] – TUBG – Candida albicans - Cryo EM<br />
-
 
+
}}
}}
[[Category:Topic Page]]
[[Category:Topic Page]]

Revision as of 07:52, 8 June 2022

3D Structures of Tubulin

Updated on 08-June-2022 - For a general description of the protein see Tubulin {{#tree:id=OrganizedByTopic|openlevels=0|

  • α-tubulin
    • 2e4h – hTUBA C terminal + restin CAP-Gly domain 2 – human
    • 6j4v - hTUBA1B + small vasohibin-binding protein + tubulinyl-Tyr carboxypeptidase
    • 2bto – PdTUBA+thioredoxin 1 – Prosthecobacter dejongeii
  • α-tubulin + β-tubulin
    • 5n5n – hTUBA-1A+hTUB-3 + GTP + GMPCPP – Cryo EM
    • 6e7b – hTUBA-1B+hTUB-3 + GTP + GMPCPP – Cryo EM
    • 7sja – hTUBA-1B+hTUB-3 + GTP – Cryo EM
    • 7sj9 – hTUBA-1B+hTUB-3 + microtubule-associated protein + GTP – Cryo EM
    • 5ij0, 7sj7, 7sj8 – hTUBA-1B+hTUB-3 + GTP + GDP – Cryo EM
    • 5ij9 – hTUBA-1B+hTUB-3 (mutant) + GTP + GDP – Cryo EM
    • [5n5n]] – hTUBA-1B+hTUB-5 + GTP + GMPCPP – Cryo EM
    • [6e7c]] – hTUBA-1B+hTUB-2B + GTP + GMPCPP – Cryo EM
    • 6i2i – hTUBA-1B +hTUB-5 + GTP + GMPCPP + stabilizer – Cryo EM
    • 7lxb, 7m18, 7m20 - hTUBA+hTUBB + GDP + GTP + drug – Cryo EM
    • 7pjf - hTUBA+hTUBB + darpin + GTP
    • 1jff - bTUBA+bTUBB - bovine
    • 6wvr, 6wvl, 6wvm - bTUBA+ bTUBB +GTP + GDP + stabilizer - Cryo EM
    • 3j6f - pTUBA+pTUBB – pig - Cryo EM
    • 3j6e, 7dmz - pTUBA+pTUBB +GMPCPP – Cryo EM
    • 3j7i - pTUBA+pTUBB +GTP – Cryo EM
    • 7sgs - pTUBA+pTUBB + esconsin + GTP – Cryo EM
    • 6o2r, 6o2q, 6o2s, 6o2t, 5xxw, 5xxv, 5xxt, 6evx, 6evz, 6ew0, 6dpv - pTUBA+pTUBB +GTP + GDP – Cryo EM
    • 6evy, 6dpw - pTUBA+pTUBB + GTPgS + GTP – Cryo EM
    • 5xxx, 7dn0 - pTUBA+pTUBB +GTP + GMPCPP – Cryo EM
    • 6dpu, 6evw - pTUBA+pTUBB + GMPCPP + GTP – Cryo EM
    • 1tub - pTUBA+pTUBB – electron diffraction
    • 5w3f, 5w3j - yTUBA+ yTUBB +GTP + GDP – yeast - Cryo EM
    • 5w3h - yTUBA+ yTUBB +GTP + GDP + stabilizer - Cryo EM
    • 2btq – PdTUBA+PdTUBB
    • 6e88 - TUBA+ TUBB +GTP + GDP – Caenorhabditis elegans - Cryo EM
    • 6ve7, 6u42 – TUBA + TUBB + GTP + GDP + stabilizer – Chlamydomonas reinhardtii - Cryo EM
    • 6u0h, 5ubq, 5ucy - TtTUBA+TUBB + GTP + GDP – Tetrahymena thermophila - Cryo EM
    • 7miz - TUBA+TUBB + SPM1 + PDI + GTP + GDP – Toxoplasma gondii - Cryo EM
  • α-tubulin + β-tubulin complexes with stathmin
    • 5lp6 – bTUBA1B +bTUBB2B +stathmin-4 + protein
    • 3du7, 3e22, 1z2b, 1sa0, 1sa1, 1ffx – bTUBA1C+bTUBB2B+stathmin-4
    • 5la6 - bTUBA+bTUBB+stathmin-4 + protein + GDP + GTP + ATP derivative + benzodioxol derivative
    • 7jfr - bTUBA+bTUBB+stathmin-4 + protein + GDP + GTP + ATP derivative + auristatin
    • 6xes, 6xet, 7lz7, 7lz8 – pTUBA1B +pTUBB +stathmin-4 + inhibitor
    • 3hkb, 3hkc, 3hkd, 3hke, 3n2g, 3n2k, 3ryc, 3ryf, 3ryh, 3ryi, 4eb6 – sTUBA+sTUBB+stathmin-4 – sheep
    • 4f61 - sTUBA+sTUBB+stathmin-like protein R4
    • 3ut5 - sTUBA+sTUBB+stathmin-4 + vinca peptide
    • 4eb6 - sTUBA+sTUBB+stathmin-4

4f6r - sTUBA+sTUBB+stathmin-like protein R1 + ankyrin repeat protein

    • 6tde - sTUBA+sTUBB+stathmin-4 + GDP + GTP
    • 6h9b - sTUBA+sTUBB+stathmin-4 + GDP + GTP + quinoline derivative
  • α-tubulin + β-tubulin complexes with stathmin and tubulin Tyr-ligase
    • 4o2a, 4iij, 4i55 - bTUBA+bTUBB+stathmin-4 + TUB-Tyr ligase
    • 4wbn, 6s9e, 6gze, 6i5c - bTUBA+bTUBB+stathmin-4 + TUB-Tyr ligase + GDP + GTP + ATP derivative
    • 5xlz - bTUBA+bTUBB+stathmin-4 + TUB-Tyr ligase + GDP + GTP + ATP derivative + anthracene derivative
    • 6qqn, 6knz - bTUBA+bTUBB+stathmin-4 + TUB-Tyr ligase + GDP + GTP + ATP derivative + pyrimidine derivative
    • 6hx8, 6gj4, 6y6d – bTUBA1B+bTUBB2B+stathmin-4 + TUB-Tyr ligase + GDP + GTP + ATP derivative + quinoline derivative
    • 6ses, 7au5, 7ogn – bTUBA1B+bTUBB2B+stathmin-4 + TUB-Tyr ligase + GDP + GTP + ATP derivative + drug
    • 6k9v, 6jcj, 6fkl, 6fkj, 6f7c, 5z4p, 5yz3, 5nfz, 5lyj, 6y4m, 6y4n, 7cbz, 7cpd, 7cpq, 7e4p, 7e4q, 7e4r, 7e4y, 7e4z – bTUBA + bTUBB + stathmin-4 + TUB-Tyr ligase + GDP + GTP + ATP derivative + inhibitor
    • 5ng1 – bTUBA + bTUBB + stathmin-4 + TUB-Tyr ligase + GDP + GTP + ATP derivative + inhibitor + stabilizer
    • 6fjf, 4tv8 - bTUBA+bTUBB+stathmin-4 + TUB-Tyr ligase + GDP + GTP + ATP derivative + maytansine
    • 4tuy, 4o4h, 4o4i, 4o4j, 4o4l, 4i50, 4i4t, 
6fii, 6fjm, 6gf3, 6qtn, 5jh7, 5bmv, 5la6, 5osk, 5jvd, 5gon, 5xlt, 5xaf, 5xag – bTUBA + bTUBB +stathmin-4 + TUB-Tyr ligase + GDP + GTP + ATP derivative + drug
    • 5iyz, 5j2t, 5j2u, 4tv9, 4yj2, 4yj3, 2xrp, 7jfr – bTUBAB1 +bTUBBB2 +stathmin-4 + TUB-Tyr ligase + GDP + GTP + ATP derivative + auristatin anti-mitotics
    • 4o2b - bTUBA+bTUBB+stathmin-4 + TUB-Tyr ligase + colchicine
    • 4ihj - bTUBA+bTUBB+stathmin-4 + tubulin Tyr-ligase + ADP
    • 7en3 - bTUBA+bTUBB+stathmin-4 + TUB-Tyr ligase + GDP + GTP + toxin
    • 4x1i, 4x1k, 4x1y, 4x20 - sTUBA+bTUBB+stathmin-4 + TUB-Tyr ligase + GDP + GTP + dolastatin + colchicine
    • 5eyp - sTUBA+sTUBB+stathmin-4 + TUB-Tyr ligase + GDP + GTP + colchicine
    • 4zhq, 4zi7, 4zol – pTUBAB1 +pTUBBB2 +stathmin-4 + TUB-Tyr ligase + GDP + GTP + ATP derivative + valinamide derivative
    • 6o5n - pTUBA+pTUBB+stathmin-4 + TUB-Tyr ligase + GDP + GTP + i
    • 6x1e, 6x1e, 6x1f, 7cld, 7cnm, 7cnn, 7dad, 7dae, 7daf, 7dp8, 7emj - pTUBA+pTUBB+stathmin-4 + TUB-Tyr ligase + GDP + GTP + drug
    • 7cno, 7l05 - pTUBA+pTUBB+stathmin-4 + TUB-Tyr ligase + GDP + GTP + toxin
    • 5jqg, 5xp3 - pTUBA+pTUBB+stathmin-4 + TUB-Tyr ligase + GDP + GTP + ATP derivative
    • 6o61, 6o5m - pTUBA+pTUBB+stathmin-4 + TUB-Tyr ligase + GDP + GTP + ATP derivative + imidazole derivative
    • 6nng, 6eg5 - pTUBA+ pTUBB+stathmin-4 + TUB-Tyr ligase + GDP + GTP + ATP derivative + pyrimidine derivative
    • 6n47 - pTUBA+ pTUBB+stathmin-4 + protein + GDP + GTP + ATP derivative + pyrimidine derivative
    • 5jcb, 5ca0, 5yl2, 5ylj, 5yls - pTUBA+ pTUBB+stathmin-4 + protein + GDP + GTP + ATP derivative + depolymerizer
    • 5cb4, 5xhc, 5xi5, 5xi7, 7cda, 7ce6, 7ce8, 7cek, 7db9, 7dba. 7dbb, 7dbc. 7dbd, 7exc – pTUBA + pTUBB + stathmin-4 + TUB-Tyr ligase + GDP + GTP + ATP derivative + inhibitor
    • 6kpp – pTUBA1B + pTUBB + stathmin-4 + TUB-Tyr ligase + GDP + GTP + benzofuran derivative
    • 5xiw – pTUBA + pTUBB +stathmin-4 + TUB-Tyr ligase + GDP + GTP + anti-gout agent
    • 6pc4, 5xkg, 5xkh, 5xke, 5xkf – pTUBA + pTUBB +stathmin-4 + TUB-Tyr ligase + GDP + GTP + anti-tumor agent
    • 5c8y, 6d88, 6br1, 6brf, 6bry, 6bs2, 5yl4 – pTUBA + pTUBB +stathmin-4 + TUB-Tyr ligase + GDP + GTP + ATP derivative + anti-tumor agent
    • 5ezy - pTUBA+ bTUBB+stathmin-4 + protein + GDP + GTP + ATP derivative + stabilizer
    • 5zxh - pTUBA+ bTUBB (mutant) +stathmin-4 + TUB-Tyr ligase + GDP + GTP + ATP derivative + imidazole derivative
    • 5z4u, 6agk, 5h7o, 5h74 – pTUBA + bTUBB + stathmin-4 + TUB-Tyr ligase + GDP + GTP + ATP derivative + inhibitor
    • 5fnv – cTUBA + rTUBB +stathmin-4 + TUB-Tyr ligase + GDP + GTP + ATP derivative + anti-tumor agent - chicken
    • 5ca1 – pTUBA + cTUBB + stathmin-4 + TUB-Tyr ligase + GDP + GTP + ATP derivative + inhibitor
  • α-tubulin + β-tubulin complex with kinesin
    • 2p4n - hTUBA+hTUBB+kinesin heavy chain
    • 6ojq – hTUBA1B+hTUBB2B+kinesin -1 heavy chain + GTP + GMPCPP – Cryo EM
    • 2wbe – bTUBA1D+bTUBB2B+kinesin+AMPPNP
    • 3dco - bTUBA+bTUBB+kinesin-like NOD
    • [4ck5]], 4ck6, 4ck7 - bTUBA+bTUBB+kinesin-like KIF11 motor domain
    • 5hnw, 5hnx, 5hny, 5hnz – bTUBAB1 +bTUBBB2 +kinesin-14 + GDP + GTP + stabilizer
    • [[3edl}} - bTUBA1D+bTUBB2B+kinesin motor domain
    • 4hna - bTUBA+bTUBB + kinesin heavy chain + ankyrin repeat protein
    • 4uxo, 4uxp, 4uxr, 4uxs, 4uxy - bTUBA+bTUBB + kinesin motor domain + GDP + GTP + stabilizer – Cryo EM
    • 4uxt, 4uy0 - bTUBA+bTUBB + kinesin heavy chain + GDP + GTP + stabilizer – Cryo EM
    • 3j2u - bTUBA+bTUBB+kinesin-like KLP10A head domain
    • 4aqv, 4aqw - bTUBA+bTUBB+kinesin-like KIF11 – Cryo EM
    • 4atx - bTUBA1D+bTUBB2B+kinesin motor domain – Cryo EM
    • 6zpi - bTUBA1D+bTUBB2B+kinesin motor domain Kif15 – Cryo EM
    • 5mm7 - bTUBA1A+bTUBB +kinesin-4 motor domain + GTP + GDP + ANP + stabilizer – Cryo EM
    • 5mm4 - bTUBA1A+bTUBB +kinesin-5 motor domain + GTP + GDP + ANP + stabilizer – Cryo EM
    • 5ogc, 5oam - bTUBA+pTUBB+kinesin-like KIF18A + GTP + GDP + stabilizer – Cryo EM
    • 5ocu - bTUBA+pTUBB+kinesin-like KIF18A + GTP + GDP + ANP + stabilizer – Cryo EM
    • 2hxf - pTUBA+pTUBB+kinesin-like KIF1A+AMPPNP
    • 6bbn - pTUBA+pTUBB+kinesin-like KIF2A + darpin + ANP + GDP + GTP
    • 3j6h - pTUBA+pTUBB +GMPCPP + kinesin heavy chain – Cryo EM
    • 3j8x - pTUBA+pTUBB +GDP + GTP + kinesin heavy chain – Cryo EM
    • 3j8y - pTUBA+pTUBB +GDP + GTP + ATP + kinesin heavy chain – Cryo EM
    • 2hxh - pTUBA+pTUBB+kinesin-like KIF1A+ADP
    • 1ia0 - pTUBA+pTUBB+kinesin-like KIF1A+ATP
    • 6tiw - pTUBA+pTUBB+kinesin-like KIF11 + GMPCPP + quinoline derivative – Cryo EM
    • 6ta4 - pTUBA+pTUBB+kinesin-like KIF11 + GTP + GMPCPP + ANP – Cryo EM
    • 6ta3 - pTUBA+pTUBB+kinesin-like KIF11 + GTP + GMPCPP + quinolin derivative – Cryo EM
    • 6b0i, 6b0i, 6b0c - pTUBA+pTUBB+kinesin-like KLP10A + GTP + GDP + stabilizer – Cryo EM
    • 6vpp - pTUBA+pTUBB+kinesin-like KLP61F + GTP + GDP – Cryo EM
    • 6vpo - pTUBA+pTUBB+kinesin-like KLP61F + GTP + GDP + ANP – Cryo EM
    • 7nb8 - pTUBA+pTUBB+kinesin-5 motor domain + GTP + G2P – Cryo EM
    • 7nba - pTUBA+pTUBB+kinesin-5 motor domain + GTP + G2P + ANP – Cryo EM
    • 6mlr - pTUBA+pTUBB+kinesin-like KIF7 + GTP + GDP + ANP + stabilizer – Cryo EM
    • 6mlq - pTUBA+pTUBB+kinesin-like KIF7 + GTP + GDP + ADP + stabilizer – Cryo EM
    • 7lvr - pTUBA+pTUBB+kinesin-like KIF14 + GTP + GDP + ADP – Cryo EM
    • 6wwe, 6wwf, 6wwg, 6wwh, 6wwi, 6wwj, 6wwk, 6wwl, 6wwm, 6wwn, 6wwo, 6wvp, 6wwq, 6wwr, 6wws, 6wwu, 6wwv, 7lvq - pTUBA+pTUBB+kinesin-like KIF14 + GTP + GDP + ANP – Cryo EM
    • 6s8m - pTUBA+pTUBB+kinesin-like CUT7 + GTP + GDP + ANP – Cryo EM
    • 4lnu - sTUBA+sTUBB + ankyrin repeat protein + GDP + GTP + kinesin heavy chain
    • 5mlv - fyTUBA+ fyTUBB+kinesin-like CUT7 + GTP + GDP + ANP – fission yeast - Cryo EM


  • α-tubulin + β-tubulin other complexes
    • 6s8l, 6s8k - hTUBA+hTUBB + ankyrin repeat protein + GDP + GTP + plinabulin
    • 6rza - hTUBA+hTUBB +GTP + GDP + stabilizer + dynein heavy chain – Cryo EM
    • 6qvj, 6qus - hTUBA+hTUBB +GTP + GDP + stabilizer + CAMSAP1 – Cryo EM
    • 6qve - hTUBA+hTUBB + GTP + GDP + stabilizer + protein – Cryo EM
    • 6quy - hTUBA+hTUBB +GTP + GDP + stabilizer + CKK – Cryo EM
    • 6wsl - hTUBA1A+hTUBB3 + small vasohibin-binding protein + tubulinyl-Tyr carboxypeptidase + GMPCPP + GTP – Cryo EM
    • 7nvnl – hTUB2A in TRIC coplex + nanobody – Cryo EM
    • 6zwb, 6zwc, 7z01, 7z02 - bTUBA+bTUBB + darpin + photoswitch + GTP + GDP
    • 7alr, 7odn - bTUBA+bTUBB + darpin + drug + GTP + GDP
    • 7z7d - bTUBA+bTUBB+GDP+GTP+ drug
    • 1tvk - bTUBA+bTUBB+GDP+GTP+ drug – electron crystallography
    • 3iz0 - bTUBA+bTUBB+hNDC80/SPC25+hNUF2/SPC24 – electron microscopy
    • 3j1t, 3j1u - bTUBA+bTUBB+ dynein
    • 4atu - bTUBA1D+bTUBB2B+doublecortin – Cryo EM
    • 6rev, 6rf2, 6rf8, 6rfd - bTUBA1B+bTUBB2B + doublecortin + GDP + GTP – Cryo EM
    • 5itz - bTUBA+bTUBB + CENP-J + darpin + GTP + GDP + colchicine
    • 5eib - bTUBA+bTUBB + CENP-J peptide + darpin + GTP + GDP
    • 7ac5 - bTUBA+ bTUBB + stathmin-like domain R1 + darpin + GDP + GTP
    • 6kiq, 6kio – pTUBA1A+pTUBB + dynein heavy chain – Cryo EM
    • 3j6p, 6rzb - pTUBA+pTUBB +GTP + GDP + stabilizer + dynein heavy chain – Cryo EM
    • 3j6g - pTUBA+pTUBB +GTP + GDP + stabilizer – Cryo EM
    • 5kmg - pTUBA+pTUBB + protein regulator + GTP + GDP – Cryo EM
    • 6cvj, [[6cvn], 7pqc, 7pqp – pTUBA1B+pTUBB + tau + GTP + GDP – Cryo EM 
**6mzg, 6mzf, 6mze - pTUBA+pTUBB + STU2P + darpin + GTP + GDP
    • 5syg, 5syf, 5sye, 5syc - pTUBA+pTUBB + STU2P + stabilizer + GTP + GDP
    • 6gx7 - sTUBA+sTUBB + alpharep + low calcium response + GTP
    • 6gwd, 6gwc - sTUBA+sTUBB + alpharep + GTP + GDP
    • 7q1e, 7q1f, 7z0f, 7z0g - sTUBA+sTUBB + alpharep + CENP-J + GTP + GDP
    • 6bjc, 6gvn - sTUBA+sTUBB + darpin + GTP
    • 6gvm - sTUBA+sTUBB + stathmin-like domain R1 + darpin + GDP + GTP
    • 4drx - sTUBA+sTUBB + ankyrin repeat protein
    • 4ffb, 4u3j - yTUBA+TUBB (mutant) + protein STU2
    • 5mjs - fyTUBA+ fyTUBB + MAL3 + GTP + GDP + ANP - Cryo EM
    • 6u0u, 6u0t - TtTUBA+TUBB+ profilament ribbon protein + GTP + GDP - Cryo EM
    • 7mwg - TtTUBA+TUBB + GTP + GDP - Cryo EM
    • 7pje - TtTUBA+TtTUBB + darpin + GTP
    • 7n32 - TtTUBA+TtTUBB + dynein + GTP + GDP – Cryo EM

γ-tubulin

3cb2 – hTUBG1+GDP 1z5v - hTUBG1+GTPgS 1z5w - hTUBG1+GTP

    • 6v6b – hTUBG2 + TUBG3 – Cryo EM
    • 6x0v – hTUBG2 + mitotic-spindle organizing protein + Cep215 – Cryo EM

3rip – hTUBG4

    • 6v69 – hTUBG4 + TUBG5 – Cryo EM
    • 6x0u – hTUBG3 + TUBG6 + mitotic spindle organizing protein – Cryo EM
    • 6l81 – hTUBG5 + mitotic-spindle organizing protein
    • 6v6c – hTUBG6 – Cryo EM
    • 6v6s – hTUBG + ADP + GDP – Cryo EM
    • 6tf9 – TUBG – frog - Cryo EM
    • 7m2w, 7m2x, 7m2y, 7m2z – yTUBG + SPC97 + SPC98 - Cryo EM
    • 6l80 – fyTUBG subunit Mod21 + mitotic-spindle organizing protein
    • 7anz – TUBG – Candida albicans - Cryo EM

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Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Jaime Prilusky, Joel L. Sussman

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