Tubulin tyrosine ligase

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 32: Line 32:
**[[5iyz]], [[5j2t]], [[5j2u]], [[5la6]], [[5bmv]], [[5jh7]], [[4tv9]], [[4yj2]], [[4yj3]], [[2xrp]], [[7jfr]] – cTTL + STM + tubulin + GTP + GDP + ATP derivative + auristatin anti-mitotics<br />
**[[5iyz]], [[5j2t]], [[5j2u]], [[5la6]], [[5bmv]], [[5jh7]], [[4tv9]], [[4yj2]], [[4yj3]], [[2xrp]], [[7jfr]] – cTTL + STM + tubulin + GTP + GDP + ATP derivative + auristatin anti-mitotics<br />
**[[5xkf]], [[5xkg]] – cTTL + STM + tubulin + GTP + GDP + inhibitor<br />
**[[5xkf]], [[5xkg]] – cTTL + STM + tubulin + GTP + GDP + inhibitor<br />
-
**[[4o2a]], [[5fnv]], [[5ca1]] – cTTL + STM + tubulin + GTP + GDP + ADP + inhibitor<br />
+
**[[4o2a]], [[5fnv]], [[5ca1]], [[7en3]] – cTTL + STM + tubulin + GTP + GDP + ADP + inhibitor<br />
-
**[[4o4l]], [[4tuy]], [[4tv8]], [[4yj2]], [[4yj3]], [[5j2t]], [[5xiw]], ]], [[6fii]], [[6fjm]], [[6gf3]], [[5jh7]], [[5bmv]], [[5la6]], [[5osk]], [[5jvd]], [[5gon]], [[5xlt]], [[5xaf]], [[5xag]], [[5jcb]], [[5c8y]], [[6d88]], [[6br1]], [[6brf]], [[6bry]], [[6bs2]], [[6pc4]], [[5xkg]], [[5xkh]], [[5xke]], [[5xkf]], [[4o4l]], [[4tuy]], [[4tv8]], [[4yj2]], [[4yj3]] – cTTL + STM + tubulin + GTP + GDP + anti-cancer drugs<br />
+
**[[4o4l]], [[4tuy]], [[4tv8]], [[4yj2]], [[4yj3]], [[5j2t]], [[5xiw]], ]], [[6fii]], [[6fjm]], [[6gf3]], [[5jh7]], [[5bmv]], [[5la6]], [[5osk]], [[5jvd]], [[5gon]], [[5xlt]], [[5xaf]], [[5xag]], [[5jcb]], [[5c8y]], [[6d88]], [[6br1]], [[6brf]], [[6bry]], [[6bs2]], [[6pc4]], [[5xkg]], [[5xkh]], [[5xke]], [[5xkf]], [[4o4l]], [[4tuy]], [[4tv8]], [[4yj2]], [[4yj3]], [[7cda]], [[7ce6]], [[7ce8]], [[7cek]], [[7db9]], [[7dba]]. [[7dbb]], [[7dbc]]. [[7dbd]], [[7exc]] – cTTL + STM + tubulin + GTP + GDP + anti-cancer drugs<br />
**[[4o4h]], [[4o4j]], [[4o4i]], [[5c8y]], [[5cb4]], [[5ca1]], [[5bmv]], [[5jh7]], [[5lxt]], [[4i4t]], [[5osk]], [[5xlt]], [[5xlz]], [[5mw1]], [[6fii]], [[6fjm]], [[5xag]], [[4i50]], [[6knz]], [[6gj4]], [[6gf3]], [[6f7c]], [[5yl4]], [[5cb4]], [[5jcb]] – cTTL + STM + tubulin + GTP + GDP + ATP derivative + anti-cancer drug<br />
**[[4o4h]], [[4o4j]], [[4o4i]], [[5c8y]], [[5cb4]], [[5ca1]], [[5bmv]], [[5jh7]], [[5lxt]], [[4i4t]], [[5osk]], [[5xlt]], [[5xlz]], [[5mw1]], [[6fii]], [[6fjm]], [[5xag]], [[4i50]], [[6knz]], [[6gj4]], [[6gf3]], [[6f7c]], [[5yl4]], [[5cb4]], [[5jcb]] – cTTL + STM + tubulin + GTP + GDP + ATP derivative + anti-cancer drug<br />
**[[6ses]] – cTTL + STM + tubulin + GTP + GDP + ATP derivative + drug<br />
**[[6ses]] – cTTL + STM + tubulin + GTP + GDP + ATP derivative + drug<br />
**[[5xlz]] - cTTL + STM + tubulin + GTP + GDP + ATP derivative + + anthracene derivative <br />
**[[5xlz]] - cTTL + STM + tubulin + GTP + GDP + ATP derivative + + anthracene derivative <br />
-
**[[6qqn]], [[6k9v]], [[6jcj]], [[6hx8]], [[6eg5]], [[6agk]], [[5zxh]], [[5z4u]], [[5z4p]], [[5yz3]], [[5h7o]], [[6o61]], [[6o5n]], [[6o5m]], [[6nng]], [[6fjf]], [[5cb4]], [[5xhc]], [[5xi5]], [[5xi7]], [[6n47]], [[5yls]], [[5jcb]], [[5ca0]], [[5yl2]], [[5ylj]], [[6fkl]], [[6fkj]], [[6kpp]], [[6y6d]], [[5yl2]], [[5ylj]], [[6br1]], [[6brf]], [[6bry]], [[6bs2]], [[6d88]], [[6fjf]], [[6fkj]], [[5xhc]], [[5xi5]], [[5xi7]], [[4zhq]], [[4zi7]], [[4zol]], [[5c8y]], [[5fnv]], [[5m7g]], [[5m8d]], [[5m8g]], [[5xlt]], [[5lov]], [[5lyj]], [[5m7e]], [[5njh]], [[5lxs]] – cTTL + STM + tubulin + GTP + GDP + ATP derivative + inhibitor<br />
+
**[[6qqn]], [[6k9v]], [[6jcj]], [[6hx8]], [[6eg5]], [[6agk]], [[5zxh]], [[5z4u]], [[5z4p]], [[5yz3]], [[5h7o]], [[6o61]], [[6o5n]], [[6o5m]], [[6nng]], [[6fjf]], [[5cb4]], [[5xhc]], [[5xi5]], [[5xi7]], [[6n47]], [[5yls]], [[5jcb]], [[5ca0]], [[5yl2]], [[5ylj]], [[6fkl]], [[6fkj]], [[6kpp]], [[6y6d]], [[5yl2]], [[5ylj]], [[6br1]], [[6brf]], [[6bry]], [[6bs2]], [[6d88]], [[6fjf]], [[6fkj]], [[5xhc]], [[5xi5]], [[5xi7]], [[4zhq]], [[4zi7]], [[4zol]], [[5c8y]], [[5fnv]], [[5m7g]], [[5m8d]], [[5m8g]], [[5xlt]], [[5lov]], [[5lyj]], [[5m7e]], [[5njh]], [[5lxs]],[[6y4m]], [[6y4n]], [[7cbz]], [[7cpd]], [[7cpq]], [[7e4p]], [[7e4q]], [[7e4r]], [[7e4y]], [[7e4z]], [[7en3]] – cTTL + STM + tubulin + GTP + GDP + ATP derivative + inhibitor<br />
 +
**[[6x1e]], [[6x1e]], [[6x1f]], [[7cld]], [[7cnm]], [[7cnn]], [[7dad]], [[7dae]], [[7daf]], [[7dp8]], [[7emj]] – cTTL + tubulin +stathmin-4 + GDP + GTP + drug<br />
 +
**[[7cno]], [[7l05]] – cTTL + tubulin + STM + GDP + GTP + toxin<br />
**[[5xiw]] – cTTL + STM + tubulin + GTP + GDP + anti-gout drug<br />
**[[5xiw]] – cTTL + STM + tubulin + GTP + GDP + anti-gout drug<br />
**[[4o2b]], [[5lp6]] – cTTL + STM + tubulin + GTP + GDP + ATP derivative + anti-gout drug<br />
**[[4o2b]], [[5lp6]] – cTTL + STM + tubulin + GTP + GDP + ATP derivative + anti-gout drug<br />

Revision as of 06:58, 9 June 2022

Tubulin tyrosine ligase (cyan) complex with α-tubulin (grey and pink), β-tubulin (green and yellow), stathmin (magenta), MES, GTP, Ca+2, Cl- and Mg+2 ions (PDB code 4iij)

Drag the structure with the mouse to rotate

3D Structures of tubulin tyrosine ligase

Updated on 09-June-2022

References

  1. ↑ Idriss HT. Phosphorylation of tubulin tyrosine ligase: a potential mechanism for regulation of alpha-tubulin tyrosination. Cell Motil Cytoskeleton. 2000 May;46(1):1-5. PMID:10842328 doi:<1::AID-CM1>3.0.CO;2-6 http://dx.doi.org/10.1002/(SICI)1097-0169(200005)46:1<1::AID-CM1>3.0.CO;2-6
  2. ↑ Szyk A, Piszczek G, Roll-Mecak A. Tubulin tyrosine ligase and stathmin compete for tubulin binding in vitro. J Mol Biol. 2013 Jul 24;425(14):2412-4. doi: 10.1016/j.jmb.2013.04.017. Epub 2013, Apr 25. PMID:23624152 doi:http://dx.doi.org/10.1016/j.jmb.2013.04.017
  3. ↑ Lafanechere L, Courtay-Cahen C, Kawakami T, Jacrot M, Rudiger M, Wehland J, Job D, Margolis RL. Suppression of tubulin tyrosine ligase during tumor growth. J Cell Sci. 1998 Jan;111 ( Pt 2):171-81. PMID:9405300
  4. ↑ Prota AE, Magiera MM, Kuijpers M, Bargsten K, Frey D, Wieser M, Jaussi R, Hoogenraad CC, Kammerer RA, Janke C, Steinmetz MO. Structural basis of tubulin tyrosination by tubulin tyrosine ligase. J Cell Biol. 2013 Feb 4;200(3):259-70. doi: 10.1083/jcb.201211017. Epub 2013 Jan , 28. PMID:23358242 doi:http://dx.doi.org/10.1083/jcb.201211017

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Joel L. Sussman, Alexander Berchansky

Retrieved from "http://52.214.119.220/wiki/index.php/Tubulin_tyrosine_ligase"
Personal tools