1ug7

<table><tr><td colspan='2'>[[1ug7]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UG7 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=1UG7 FirstGlance]. <br>

</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">RIKEN cDNA 2610208M17 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=1ug7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ug7 OCA], [http://pdbe.org/1ug7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1ug7 RCSB], [http://www.ebi.ac.uk/pdbsum/1ug7 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1ug7 ProSAT], [http://www.topsan.org/Proteins/RSGI/1ug7 TOPSAN]</span></td></tr>

[[http://www.uniprot.org/uniprot/AIDA_MOUSE AIDA_MOUSE]] Acts as a ventralizing factor during embryogenesis (By similarity). Inhibits axin-mediated JNK activation by binding axin and disrupting axin homodimerization. This in turn antagonizes a Wnt/beta-catenin-independent dorsalization pathway activated by AXIN/JNK-signaling.