This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
3rey
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
==Thermostabilised adenosine A2A receptor in complex with XAC== | ==Thermostabilised adenosine A2A receptor in complex with XAC== | ||
| - | <StructureSection load='3rey' size='340' side='right' caption='[[3rey]], [[Resolution|resolution]] 3.31Å' scene=''> | + | <StructureSection load='3rey' size='340' side='right'caption='[[3rey]], [[Resolution|resolution]] 3.31Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3rey]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[3rey]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3REY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3REY FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=XAC:N-(2-AMINOETHYL)-2-[4-(2,6-DIOXO-1,3-DIPROPYL-2,3,6,7-TETRAHYDRO-1H-PURIN-8-YL)PHENOXY]ACETAMIDE'>XAC</scene></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=XAC:N-(2-AMINOETHYL)-2-[4-(2,6-DIOXO-1,3-DIPROPYL-2,3,6,7-TETRAHYDRO-1H-PURIN-8-YL)PHENOXY]ACETAMIDE'>XAC</scene></td></tr> |
| - | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3pwh|3pwh]], [[3rfm|3rfm]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3pwh|3pwh]], [[3rfm|3rfm]]</div></td></tr> |
| - | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ADORA2A ([ | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ADORA2A ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3rey FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rey OCA], [https://pdbe.org/3rey PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3rey RCSB], [https://www.ebi.ac.uk/pdbsum/3rey PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3rey ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/AA2AR_HUMAN AA2AR_HUMAN]] Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. |
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
| Line 22: | Line 22: | ||
==See Also== | ==See Also== | ||
| - | *[[Adenosine A2A receptor|Adenosine A2A receptor | + | *[[Adenosine A2A receptor 3D structures|Adenosine A2A receptor 3D structures]] |
| - | + | ||
== References == | == References == | ||
<references/> | <references/> | ||
| Line 29: | Line 28: | ||
</StructureSection> | </StructureSection> | ||
[[Category: Human]] | [[Category: Human]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Bennett, K]] | [[Category: Bennett, K]] | ||
[[Category: Congreve, M]] | [[Category: Congreve, M]] | ||
Revision as of 06:00, 15 June 2022
Thermostabilised adenosine A2A receptor in complex with XAC
| |||||||||||
Categories: Human | Large Structures | Bennett, K | Congreve, M | Dore, A S | Errey, J C | Hollenstein, K | Hurrell, E | Magnani, F | Marshall, F H | Ng, I | Robertson, N | Tate, C G | Tehan, B | Weir, M | G-protein | Gpcr | Membrane protein | Signaling protein
