UDP-N-acetylglucosamine acyltransferase

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**[[5dep]], [[5dg3]] – PaLpxA + UDP-GlcNAc derivative<br />
**[[5dep]], [[5dg3]] – PaLpxA + UDP-GlcNAc derivative<br />
 +
**[[6ueg]], [[7oj6]], [[7ojp]], [[7ojq]], [[7ojw]], [[7ojy]], [[7ok1]], [[7ok2]], [[7oka]], [[7okb]] – PaLpxA + inhibitor<br />
**[[4r37]] – BfLpxA + UDP-GlcNAc <br />
**[[4r37]] – BfLpxA + UDP-GlcNAc <br />
**[[6uec]], [[6uee]], [[6ueg]] – PaLpxA + ligand<br />
**[[6uec]], [[6uee]], [[6ueg]] – PaLpxA + ligand<br />

Revision as of 08:04, 20 June 2022

E. coli UDP-N-acetylglucosamine acyltransferase complex with UDP-Glc-NAC (PDB code 2jf3)

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3D structures of UDP-N-acetylglucosamine acyltransferase

Updated on 20-June-2022

References

  1. Wyckoff TJ, Raetz CR. The active site of Escherichia coli UDP-N-acetylglucosamine acyltransferase. Chemical modification and site-directed mutagenesis. J Biol Chem. 1999 Sep 17;274(38):27047-55. PMID:10480918
  2. Ulaganathan V, Buetow L, Hunter WN. Nucleotide substrate recognition by UDP-N-acetylglucosamine acyltransferase (LpxA) in the first step of lipid A biosynthesis. J Mol Biol. 2007 Jun 1;369(2):305-12. Epub 2007 Mar 21. PMID:17434525 doi:10.1016/j.jmb.2007.03.039

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Michal Harel, Alexander Berchansky, Joel L. Sussman

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