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3rjr

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Current revision (10:13, 22 June 2022) (edit) (undo)
 
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==Crystal Structure of pro-TGF beta 1==
==Crystal Structure of pro-TGF beta 1==
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<StructureSection load='3rjr' size='340' side='right' caption='[[3rjr]], [[Resolution|resolution]] 3.05&Aring;' scene=''>
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<StructureSection load='3rjr' size='340' side='right'caption='[[3rjr]], [[Resolution|resolution]] 3.05&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3rjr]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Pig Pig]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RJR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3RJR FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3rjr]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Pig Pig]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RJR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3RJR FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">TGFB1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9823 PIG])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">TGFB1 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9823 PIG])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3rjr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rjr OCA], [http://pdbe.org/3rjr PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3rjr RCSB], [http://www.ebi.ac.uk/pdbsum/3rjr PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3rjr ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3rjr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rjr OCA], [https://pdbe.org/3rjr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3rjr RCSB], [https://www.ebi.ac.uk/pdbsum/3rjr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3rjr ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/TGFB1_PIG TGFB1_PIG]] Multifunctional protein that controls proliferation, differentiation and other functions in many cell types. Many cells synthesize TGFB1 and have specific receptors for it. It positively and negatively regulates many other growth factors. It plays an important role in bone remodeling as it is a potent stimulator of osteoblastic bone formation, causing chemotaxis, proliferation and differentiation in committed osteoblasts (By similarity).
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[[https://www.uniprot.org/uniprot/TGFB1_PIG TGFB1_PIG]] Multifunctional protein that controls proliferation, differentiation and other functions in many cell types. Many cells synthesize TGFB1 and have specific receptors for it. It positively and negatively regulates many other growth factors. It plays an important role in bone remodeling as it is a potent stimulator of osteoblastic bone formation, causing chemotaxis, proliferation and differentiation in committed osteoblasts (By similarity).
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Large Structures]]
[[Category: Pig]]
[[Category: Pig]]
[[Category: Shi, M L]]
[[Category: Shi, M L]]

Current revision

Crystal Structure of pro-TGF beta 1

PDB ID 3rjr

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