3rk4

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==Structure of Rhodococcus rhodochrous haloalkane dehalogenase mutant DhaA31==
==Structure of Rhodococcus rhodochrous haloalkane dehalogenase mutant DhaA31==
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<StructureSection load='3rk4' size='340' side='right' caption='[[3rk4]], [[Resolution|resolution]] 1.31&Aring;' scene=''>
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<StructureSection load='3rk4' size='340' side='right'caption='[[3rk4]], [[Resolution|resolution]] 1.31&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3rk4]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacterium_mycoides_roseum"_grotenfelt_1889 "bacterium mycoides roseum" grotenfelt 1889]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RK4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3RK4 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3rk4]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacterium_mycoides_roseum"_grotenfelt_1889 "bacterium mycoides roseum" grotenfelt 1889]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RK4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3RK4 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3fbw|3fbw]], [[3g9x|3g9x]], [[3fwh|3fwh]], [[1bn6|1bn6]], [[1cqw|1cqw]], [[3rlt|3rlt]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3fbw|3fbw]], [[3g9x|3g9x]], [[3fwh|3fwh]], [[1bn6|1bn6]], [[1cqw|1cqw]], [[3rlt|3rlt]]</div></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">dhaA, DhaA31 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1829 "Bacterium mycoides roseum" Grotenfelt 1889])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">dhaA, DhaA31 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1829 "Bacterium mycoides roseum" Grotenfelt 1889])</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Haloalkane_dehalogenase Haloalkane dehalogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.8.1.5 3.8.1.5] </span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Haloalkane_dehalogenase Haloalkane dehalogenase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.8.1.5 3.8.1.5] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3rk4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rk4 OCA], [http://pdbe.org/3rk4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3rk4 RCSB], [http://www.ebi.ac.uk/pdbsum/3rk4 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3rk4 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3rk4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rk4 OCA], [https://pdbe.org/3rk4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3rk4 RCSB], [https://www.ebi.ac.uk/pdbsum/3rk4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3rk4 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/DHAA_RHORH DHAA_RHORH]] Catalyzes hydrolytic cleavage of carbon-halogen bonds in halogenated aliphatic compounds, leading to the formation of the corresponding primary alcohols, halide ions and protons. Expresses halogenase activity against 1-chloroalkanes of chain length C3 to C10, and also shows a very weak activity with 1,2-dichloroethane.
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[[https://www.uniprot.org/uniprot/DHAA_RHORH DHAA_RHORH]] Catalyzes hydrolytic cleavage of carbon-halogen bonds in halogenated aliphatic compounds, leading to the formation of the corresponding primary alcohols, halide ions and protons. Expresses halogenase activity against 1-chloroalkanes of chain length C3 to C10, and also shows a very weak activity with 1,2-dichloroethane.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 3rk4" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 3rk4" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Dehalogenase 3D structures|Dehalogenase 3D structures]]
== References ==
== References ==
<references/>
<references/>
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[[Category: Bacterium mycoides roseum grotenfelt 1889]]
[[Category: Bacterium mycoides roseum grotenfelt 1889]]
[[Category: Haloalkane dehalogenase]]
[[Category: Haloalkane dehalogenase]]
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[[Category: Large Structures]]
[[Category: Chaloupkova, R]]
[[Category: Chaloupkova, R]]
[[Category: Damborsky, J]]
[[Category: Damborsky, J]]

Revision as of 10:14, 22 June 2022

Structure of Rhodococcus rhodochrous haloalkane dehalogenase mutant DhaA31

PDB ID 3rk4

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