3rks
From Proteopedia
(Difference between revisions)
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==Crystal Structure of the Manihot esculenta Hydroxynitrile Lyase (MeHNL) K176P mutant== | ==Crystal Structure of the Manihot esculenta Hydroxynitrile Lyase (MeHNL) K176P mutant== | ||
| - | <StructureSection load='3rks' size='340' side='right' caption='[[3rks]], [[Resolution|resolution]] 2.50Å' scene=''> | + | <StructureSection load='3rks' size='340' side='right'caption='[[3rks]], [[Resolution|resolution]] 2.50Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3rks]] is a 4 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[3rks]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Cassava Cassava]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RKS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3RKS FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr> |
| - | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3rkt|3rkt]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3rkt|3rkt]]</div></td></tr> |
| - | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">HNL ([ | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">HNL ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=3983 Cassava])</td></tr> |
| - | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Lyase Lyase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.2.46 and 4.1.2.47 4.1.2.46 and 4.1.2.47] </span></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3rks FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rks OCA], [https://pdbe.org/3rks PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3rks RCSB], [https://www.ebi.ac.uk/pdbsum/3rks PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3rks ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/HNL_MANES HNL_MANES]] Involved in cyanogenesis, the release of HCN from injured tissues. Decomposes a varieties of (R) or (S) cyanohydrins into HCN and the corresponding aldehydes and ketones. The natural substrate of this enzyme is (S)-acetone cyanohydrin. |
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Cassava]] | [[Category: Cassava]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Lyase]] | [[Category: Lyase]] | ||
[[Category: Asano, Y]] | [[Category: Asano, Y]] | ||
Revision as of 10:14, 22 June 2022
Crystal Structure of the Manihot esculenta Hydroxynitrile Lyase (MeHNL) K176P mutant
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