3s0k

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==Crystal Structure of Human Glycolipid Transfer Protein complexed with glucosylceramide containing oleoyl acyl chain (18:1)==
==Crystal Structure of Human Glycolipid Transfer Protein complexed with glucosylceramide containing oleoyl acyl chain (18:1)==
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<StructureSection load='3s0k' size='340' side='right' caption='[[3s0k]], [[Resolution|resolution]] 1.40&Aring;' scene=''>
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<StructureSection load='3s0k' size='340' side='right'caption='[[3s0k]], [[Resolution|resolution]] 1.40&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3s0k]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3S0K OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3S0K FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3s0k]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3S0K OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3S0K FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=03F:(9Z)-N-[(2S,3R,4E)-1-(BETA-D-GLUCOPYRANOSYLOXY)-3-HYDROXYOCTADEC-4-EN-2-YL]OCTADEC-9-ENAMIDE'>03F</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=03F:(9Z)-N-[(2S,3R,4E)-1-(BETA-D-GLUCOPYRANOSYLOXY)-3-HYDROXYOCTADEC-4-EN-2-YL]OCTADEC-9-ENAMIDE'>03F</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3rwv|3rwv]], [[2euk|2euk]], [[1swx|1swx]], [[3rzn|3rzn]], [[3ric|3ric]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3rwv|3rwv]], [[2euk|2euk]], [[1swx|1swx]], [[3rzn|3rzn]], [[3ric|3ric]]</div></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">GLTP ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">GLTP ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3s0k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3s0k OCA], [http://pdbe.org/3s0k PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3s0k RCSB], [http://www.ebi.ac.uk/pdbsum/3s0k PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3s0k ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3s0k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3s0k OCA], [https://pdbe.org/3s0k PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3s0k RCSB], [https://www.ebi.ac.uk/pdbsum/3s0k PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3s0k ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/GLTP_HUMAN GLTP_HUMAN]] Accelerates the intermembrane transfer of various glycolipids. Catalyzes the transfer of various glycosphingolipids between membranes but does not catalyze the transfer of phospholipids. May be involved in the intracellular translocation of glucosylceramides.<ref>PMID:18261224</ref> <ref>PMID:15504043</ref> <ref>PMID:17980653</ref> <ref>PMID:15329726</ref>
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[[https://www.uniprot.org/uniprot/GLTP_HUMAN GLTP_HUMAN]] Accelerates the intermembrane transfer of various glycolipids. Catalyzes the transfer of various glycosphingolipids between membranes but does not catalyze the transfer of phospholipids. May be involved in the intracellular translocation of glucosylceramides.<ref>PMID:18261224</ref> <ref>PMID:15504043</ref> <ref>PMID:17980653</ref> <ref>PMID:15329726</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Human]]
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[[Category: Large Structures]]
[[Category: Brown, R E]]
[[Category: Brown, R E]]
[[Category: Cabo-Bilbao, A]]
[[Category: Cabo-Bilbao, A]]

Revision as of 10:32, 22 June 2022

Crystal Structure of Human Glycolipid Transfer Protein complexed with glucosylceramide containing oleoyl acyl chain (18:1)

PDB ID 3s0k

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