3s93

<StructureSection load='3s93' size='340' side='right' caption='[[3s93]], [[Resolution|resolution]] 2.28&Aring;' scene=''>

<table><tr><td colspan='2'>[[3s93]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3S93 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3S93 FirstGlance]. <br>

</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr>

<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">TDRD5 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3s93 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3s93 OCA], [http://pdbe.org/3s93 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3s93 RCSB], [http://www.ebi.ac.uk/pdbsum/3s93 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3s93 ProSAT]</span></td></tr>

[[http://www.uniprot.org/uniprot/TDRD5_HUMAN TDRD5_HUMAN]] Required during spermiogenesis to participate in the repression transposable elements and prevent their mobilization, which is essential for the germline integrity. Probably acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Required for chromatoid body (CB) assembly (By similarity).