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1hjz

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[[Image:1hjz.jpg|left|200px]]
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{{Structure
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|SITE= <scene name='pdbsite=AC1:Mes+Binding+Site+For+Chain+B'>AC1</scene>
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|LIGAND= <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>
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{{STRUCTURE_1hjz| PDB=1hjz | SCENE= }}
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1hjz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hjz OCA], [http://www.ebi.ac.uk/pdbsum/1hjz PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1hjz RCSB]</span>
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'''CRYSTAL STRUCTURE OF AF1521 PROTEIN CONTAINING A MACROH2A DOMAIN'''
'''CRYSTAL STRUCTURE OF AF1521 PROTEIN CONTAINING A MACROH2A DOMAIN'''
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[[Category: Cordell, S C.]]
[[Category: Cordell, S C.]]
[[Category: Lowe, J.]]
[[Category: Lowe, J.]]
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[[Category: crystal structure p-loop nucleotide hydrolase]]
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[[Category: Crystal structure p-loop nucleotide hydrolase]]
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[[Category: histone macroh2a]]
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[[Category: Histone macroh2a]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 18:55:33 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 21:06:24 2008''
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Revision as of 15:55, 2 May 2008

Image:1hjz.jpg

Template:STRUCTURE 1hjz

CRYSTAL STRUCTURE OF AF1521 PROTEIN CONTAINING A MACROH2A DOMAIN


Overview

MacroH2A is an unusual histone H2A variant that has an extensive C-terminal tail that comprises approximately two thirds of the protein. The C-terminal non-histone domain of macroH2A is also found in a number of other proteins and has been termed the macro domain. Here we report the crystal structure to 1.7A of AF1521, a protein consisting of a stand-alone macro domain from Archaeoglobus fulgidus. The structure has a mixed alpha/beta fold that closely resembles the N-terminal DNA binding domain of the Escherichia coli leucine aminopeptidase PepA. The structure also shows some similarity to members of the P-loop family of nucleotide hydrolases.

About this Structure

1HJZ is a Single protein structure of sequence from Archaeoglobus fulgidus. Full crystallographic information is available from OCA.

Reference

The crystal structure of AF1521 a protein from Archaeoglobus fulgidus with homology to the non-histone domain of macroH2A., Allen MD, Buckle AM, Cordell SC, Lowe J, Bycroft M, J Mol Biol. 2003 Jul 11;330(3):503-11. PMID:12842467 Page seeded by OCA on Fri May 2 18:55:33 2008

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