7wda
From Proteopedia
(Difference between revisions)
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==Crystal structure LpqY in complex with Trehalose from Mycobacterium tuberculosis== | ==Crystal structure LpqY in complex with Trehalose from Mycobacterium tuberculosis== | ||
| - | <StructureSection load='7wda' size='340' side='right'caption='[[7wda]]' scene=''> | + | <StructureSection load='7wda' size='340' side='right'caption='[[7wda]], [[Resolution|resolution]] 1.91Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7WDA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7WDA FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[7wda]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7WDA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7WDA FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7wda FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7wda OCA], [https://pdbe.org/7wda PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7wda RCSB], [https://www.ebi.ac.uk/pdbsum/7wda PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7wda ProSAT]</span></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7wda FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7wda OCA], [https://pdbe.org/7wda PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7wda RCSB], [https://www.ebi.ac.uk/pdbsum/7wda PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7wda ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[https://www.uniprot.org/uniprot/LPQY_MYCTU LPQY_MYCTU]] Part of the ABC transporter complex LpqY-SugA-SugB-SugC, which is highly specific for uptake of trehalose. Involved in the recycling of extracellular trehalose released from trehalose-containing molecules synthesized by M.tuberculosis. Trehalose uptake is essential for virulence.<ref>PMID:21118978</ref> | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Das U]] | + | [[Category: Das, U]] |
| - | [[Category: Sharma D]] | + | [[Category: Sharma, D]] |
| + | [[Category: Lpqy]] | ||
| + | [[Category: Mycobacterium tuberculosis]] | ||
| + | [[Category: Sugabc]] | ||
| + | [[Category: Sugar binding protein]] | ||
| + | [[Category: Trehalose]] | ||
Revision as of 07:35, 29 June 2022
Crystal structure LpqY in complex with Trehalose from Mycobacterium tuberculosis
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