3t7l
From Proteopedia
(Difference between revisions)
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==Crystal structure of the FYVE domain of endofin (ZFYVE16) at 1.1A resolution== | ==Crystal structure of the FYVE domain of endofin (ZFYVE16) at 1.1A resolution== | ||
| - | <StructureSection load='3t7l' size='340' side='right' caption='[[3t7l]], [[Resolution|resolution]] 1.09Å' scene=''> | + | <StructureSection load='3t7l' size='340' side='right'caption='[[3t7l]], [[Resolution|resolution]] 1.09Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3t7l]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[3t7l]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T7L OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3T7L FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> |
| - | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">KIAA0305, ZFYVE16 ([ | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">KIAA0305, ZFYVE16 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3t7l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3t7l OCA], [https://pdbe.org/3t7l PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3t7l RCSB], [https://www.ebi.ac.uk/pdbsum/3t7l PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3t7l ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/ZFY16_HUMAN ZFY16_HUMAN]] May be involved in regulating membrane trafficking in the endosomal pathway. Overexpression induces endosome aggregation. Required to target TOM1 to endosomes.<ref>PMID:11546807</ref> <ref>PMID:14613930</ref> |
== References == | == References == | ||
<references/> | <references/> | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Human]] | [[Category: Human]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Arrowsmith, C H]] | [[Category: Arrowsmith, C H]] | ||
[[Category: Berridge, G]] | [[Category: Berridge, G]] | ||
Revision as of 16:46, 6 July 2022
Crystal structure of the FYVE domain of endofin (ZFYVE16) at 1.1A resolution
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Categories: Human | Large Structures | Arrowsmith, C H | Berridge, G | Bountra, C | Bullock, A | Canning, P | Chaikuad, A | Delft, F von | Edwards, A M | Guo, K | Krojer, T | Muniz, J R.C | Phillips, C | Structural genomic | Sanvitale, C | Shrestha, A | Weigelt, J | Williams, E | Lipid binding protein | Sgc | Transport protein | Zinc finger
