1hnw

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
[[Image:1hnw.gif|left|200px]]
[[Image:1hnw.gif|left|200px]]
-
{{Structure
+
<!--
-
|PDB= 1hnw |SIZE=350|CAPTION= <scene name='initialview01'>1hnw</scene>, resolution 3.40&Aring;
+
The line below this paragraph, containing "STRUCTURE_1hnw", creates the "Structure Box" on the page.
-
|SITE=
+
You may change the PDB parameter (which sets the PDB file loaded into the applet)
-
|LIGAND= <scene name='pdbligand=A:ADENOSINE-5&#39;-MONOPHOSPHATE'>A</scene>, <scene name='pdbligand=C:CYTIDINE-5&#39;-MONOPHOSPHATE'>C</scene>, <scene name='pdbligand=G:GUANOSINE-5&#39;-MONOPHOSPHATE'>G</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=TAC:TETRACYCLINE'>TAC</scene>, <scene name='pdbligand=U:URIDINE-5&#39;-MONOPHOSPHATE'>U</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>
+
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-
|ACTIVITY=
+
or leave the SCENE parameter empty for the default display.
-
|GENE=
+
-->
-
|DOMAIN=
+
{{STRUCTURE_1hnw| PDB=1hnw | SCENE= }}
-
|RELATEDENTRY=[[1qd7|1QD7]], [[1fjf|1FJF]], [[1fjg|1FJG]], [[1hnx|1HNX]], [[1hnz|1HNZ]]
+
-
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1hnw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hnw OCA], [http://www.ebi.ac.uk/pdbsum/1hnw PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1hnw RCSB]</span>
+
-
}}
+
'''STRUCTURE OF THE THERMUS THERMOPHILUS 30S RIBOSOMAL SUBUNIT IN COMPLEX WITH TETRACYCLINE'''
'''STRUCTURE OF THE THERMUS THERMOPHILUS 30S RIBOSOMAL SUBUNIT IN COMPLEX WITH TETRACYCLINE'''
Line 32: Line 29:
[[Category: Wimberly, B T.]]
[[Category: Wimberly, B T.]]
[[Category: 30s ribosomal subunit]]
[[Category: 30s ribosomal subunit]]
-
[[Category: antibiotic]]
+
[[Category: Antibiotic]]
-
[[Category: ribosome]]
+
[[Category: Ribosome]]
-
[[Category: tetracycline]]
+
[[Category: Tetracycline]]
-
 
+
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 19:03:13 2008''
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 21:08:09 2008''
+

Revision as of 16:03, 2 May 2008

Image:1hnw.gif

Template:STRUCTURE 1hnw

STRUCTURE OF THE THERMUS THERMOPHILUS 30S RIBOSOMAL SUBUNIT IN COMPLEX WITH TETRACYCLINE


Overview

We have used the recently determined atomic structure of the 30S ribosomal subunit to determine the structures of its complexes with the antibiotics tetracycline, pactamycin, and hygromycin B. The antibiotics bind to discrete sites on the 30S subunit in a manner consistent with much but not all biochemical data. For each of these antibiotics, interactions with the 30S subunit suggest a mechanism for its effects on ribosome function.

About this Structure

1HNW is a Protein complex structure of sequences from Thermus thermophilus. Full crystallographic information is available from OCA.

Reference

The structural basis for the action of the antibiotics tetracycline, pactamycin, and hygromycin B on the 30S ribosomal subunit., Brodersen DE, Clemons WM Jr, Carter AP, Morgan-Warren RJ, Wimberly BT, Ramakrishnan V, Cell. 2000 Dec 22;103(7):1143-54. PMID:11163189 Page seeded by OCA on Fri May 2 19:03:13 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1hnw"
Personal tools