3klp
From Proteopedia
(Difference between revisions)
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<StructureSection load='3klp' size='340' side='right'caption='[[3klp]], [[Resolution|resolution]] 2.50Å' scene=''> | <StructureSection load='3klp' size='340' side='right'caption='[[3klp]], [[Resolution|resolution]] 2.50Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3klp]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[3klp]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KLP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3KLP FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=B81:(3ALPHA,8ALPHA,17BETA)-ANDROST-5-ENE-3,17-DIOL'>B81</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=B81:(3ALPHA,8ALPHA,17BETA)-ANDROST-5-ENE-3,17-DIOL'>B81</scene></td></tr> | ||
| - | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/17-beta-estradiol_17-dehydrogenase 17-beta-estradiol 17-dehydrogenase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.62 1.1.1.62] </span></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3klp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3klp OCA], [https://pdbe.org/3klp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3klp RCSB], [https://www.ebi.ac.uk/pdbsum/3klp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3klp ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/DHB1_HUMAN DHB1_HUMAN]] Favors the reduction of estrogens and androgens. Also has 20-alpha-HSD activity. Uses preferentially NADH. |
==See Also== | ==See Also== | ||
Revision as of 05:40, 13 July 2022
17beta-HSD1 in complex with A-diol
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