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3tw2
From Proteopedia
(Difference between revisions)
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==High resolution structure of human histidine triad nucleotide-binding protein 1 (hHINT1)/AMP complex in a monoclinic space group== | ==High resolution structure of human histidine triad nucleotide-binding protein 1 (hHINT1)/AMP complex in a monoclinic space group== | ||
| - | <StructureSection load='3tw2' size='340' side='right' caption='[[3tw2]], [[Resolution|resolution]] 1.38Å' scene=''> | + | <StructureSection load='3tw2' size='340' side='right'caption='[[3tw2]], [[Resolution|resolution]] 1.38Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3tw2]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[3tw2]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TW2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3TW2 FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=AMP:ADENOSINE+MONOPHOSPHATE'>AMP</scene></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AMP:ADENOSINE+MONOPHOSPHATE'>AMP</scene></td></tr> |
| - | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1av5|1av5]], [[1kpe|1kpe]], [[1kpf|1kpf]], [[1kpa|1kpa]], [[1kpb|1kpb]], [[1kpc|1kpc]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1av5|1av5]], [[1kpe|1kpe]], [[1kpf|1kpf]], [[1kpa|1kpa]], [[1kpb|1kpb]], [[1kpc|1kpc]]</div></td></tr> |
| - | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">HINT1, HINT, PKCI1, PRKCNH1 ([ | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">HINT1, HINT, PKCI1, PRKCNH1 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3tw2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tw2 OCA], [https://pdbe.org/3tw2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3tw2 RCSB], [https://www.ebi.ac.uk/pdbsum/3tw2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3tw2 ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/HINT1_HUMAN HINT1_HUMAN]] Hydrolyzes adenosine 5'-monophosphoramidate substrates such as AMP-morpholidate, AMP-N-alanine methyl ester, AMP-alpha-acetyl lysine methyl ester and AMP-NH2 (By similarity). |
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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==See Also== | ==See Also== | ||
| - | *[[Histidine triad nucleotide-binding protein|Histidine triad nucleotide-binding protein]] | + | *[[Histidine triad nucleotide-binding protein 3D structures|Histidine triad nucleotide-binding protein 3D structures]] |
== References == | == References == | ||
<references/> | <references/> | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Human]] | [[Category: Human]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Dolot, R M]] | [[Category: Dolot, R M]] | ||
[[Category: Krakowiak, A]] | [[Category: Krakowiak, A]] | ||
Revision as of 05:47, 13 July 2022
High resolution structure of human histidine triad nucleotide-binding protein 1 (hHINT1)/AMP complex in a monoclinic space group
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Categories: Human | Large Structures | Dolot, R M | Krakowiak, A | Nawrot, B | Ozga, M | Wlodarczyk, A | Hydrolase
