3u43

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==Crystal structure of the colicin E2 DNase-Im2 complex==
==Crystal structure of the colicin E2 DNase-Im2 complex==
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<StructureSection load='3u43' size='340' side='right' caption='[[3u43]], [[Resolution|resolution]] 1.72&Aring;' scene=''>
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<StructureSection load='3u43' size='340' side='right'caption='[[3u43]], [[Resolution|resolution]] 1.72&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3u43]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3U43 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3U43 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3u43]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3U43 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3U43 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">imm, ceiB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895]), col, ceaB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">imm, ceiB ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895]), col, ceaB ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3u43 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3u43 OCA], [http://pdbe.org/3u43 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3u43 RCSB], [http://www.ebi.ac.uk/pdbsum/3u43 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3u43 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3u43 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3u43 OCA], [https://pdbe.org/3u43 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3u43 RCSB], [https://www.ebi.ac.uk/pdbsum/3u43 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3u43 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/IMM2_ECOLX IMM2_ECOLX]] This protein is able to protect a cell, which harbors the plasmid ColE2 encoding colicin E2, against colicin E2. [[http://www.uniprot.org/uniprot/CEA2_ECOLX CEA2_ECOLX]] This plasmid-coded bactericidal protein is an endonuclease active on both single- and double-stranded DNA but with undefined specificity. Colicins are polypeptide toxins produced by and active against E.coli and closely related bacteria.
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[[https://www.uniprot.org/uniprot/IMM2_ECOLX IMM2_ECOLX]] This protein is able to protect a cell, which harbors the plasmid ColE2 encoding colicin E2, against colicin E2. [[https://www.uniprot.org/uniprot/CEA2_ECOLX CEA2_ECOLX]] This plasmid-coded bactericidal protein is an endonuclease active on both single- and double-stranded DNA but with undefined specificity. Colicins are polypeptide toxins produced by and active against E.coli and closely related bacteria.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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==See Also==
==See Also==
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*[[Colicin|Colicin]]
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*[[Colicin 3D structures|Colicin 3D structures]]
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*[[Colicin Immunity Protein|Colicin Immunity Protein]]
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*[[Colicin immunity protein 3D structures|Colicin immunity protein 3D structures]]
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Bacillus coli migula 1895]]
[[Category: Bacillus coli migula 1895]]
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[[Category: Large Structures]]
[[Category: Kleanthous, C]]
[[Category: Kleanthous, C]]
[[Category: Wojdyla, J A]]
[[Category: Wojdyla, J A]]

Revision as of 05:56, 13 July 2022

Crystal structure of the colicin E2 DNase-Im2 complex

PDB ID 3u43

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