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3ucs

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==Crystal structure of the complex between CBPA J-domain and CBPM==
==Crystal structure of the complex between CBPA J-domain and CBPM==
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<StructureSection load='3ucs' size='340' side='right' caption='[[3ucs]], [[Resolution|resolution]] 1.87&Aring;' scene=''>
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<StructureSection load='3ucs' size='340' side='right'caption='[[3ucs]], [[Resolution|resolution]] 1.87&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3ucs]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli] and [http://en.wikipedia.org/wiki/Klep3 Klep3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UCS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3UCS FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3ucs]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Ecoli Ecoli] and [https://en.wikipedia.org/wiki/Klep3 Klep3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UCS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3UCS FirstGlance]. <br>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">cbpM, KPK_5158 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=507522 KLEP3]), b1000, cbpA, JW0985 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI])</td></tr>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">cbpM, KPK_5158 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=507522 KLEP3]), b1000, cbpA, JW0985 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ucs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ucs OCA], [http://pdbe.org/3ucs PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3ucs RCSB], [http://www.ebi.ac.uk/pdbsum/3ucs PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3ucs ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ucs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ucs OCA], [https://pdbe.org/3ucs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ucs RCSB], [https://www.ebi.ac.uk/pdbsum/3ucs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ucs ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/CBPA_ECOLI CBPA_ECOLI]] DNA-binding protein that preferentially recognizes a curved DNA sequence. It is probably a functional analog of DnaJ; displays overlapping activities with DnaJ, but functions under different conditions, probably acting as a molecular chaperone in an adaptive response to environmental stresses other than heat shock. Lacks autonomous chaperone activity; binds native substrates and targets them for recognition by DnaK. Its activity is inhibited by the binding of CbpM.<ref>PMID:7601860</ref> <ref>PMID:8824642</ref>
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[[https://www.uniprot.org/uniprot/CBPA_ECOLI CBPA_ECOLI]] DNA-binding protein that preferentially recognizes a curved DNA sequence. It is probably a functional analog of DnaJ; displays overlapping activities with DnaJ, but functions under different conditions, probably acting as a molecular chaperone in an adaptive response to environmental stresses other than heat shock. Lacks autonomous chaperone activity; binds native substrates and targets them for recognition by DnaK. Its activity is inhibited by the binding of CbpM.<ref>PMID:7601860</ref> <ref>PMID:8824642</ref>
== References ==
== References ==
<references/>
<references/>
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[[Category: Ecoli]]
[[Category: Ecoli]]
[[Category: Klep3]]
[[Category: Klep3]]
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[[Category: Large Structures]]
[[Category: Structural genomic]]
[[Category: Structural genomic]]
[[Category: Cygler, M]]
[[Category: Cygler, M]]

Revision as of 06:07, 13 July 2022

Crystal structure of the complex between CBPA J-domain and CBPM

PDB ID 3ucs

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