6zc7
From Proteopedia
(Difference between revisions)
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==Small-molecule inhibitors of the PDZ domain of Dishevelled proteins interrupt Wnt signalling== | ==Small-molecule inhibitors of the PDZ domain of Dishevelled proteins interrupt Wnt signalling== | ||
| - | <StructureSection load='6zc7' size='340' side='right'caption='[[6zc7]]' scene=''> | + | <StructureSection load='6zc7' size='340' side='right'caption='[[6zc7]], [[Resolution|resolution]] 1.48Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6ZC7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6ZC7 FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[6zc7]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6ZC7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6ZC7 FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6zc7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6zc7 OCA], [https://pdbe.org/6zc7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6zc7 RCSB], [https://www.ebi.ac.uk/pdbsum/6zc7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6zc7 ProSAT]</span></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=V31:5-bromanyl-2-[(phenylmethyl)sulfonylamino]benzoic+acid'>V31</scene></td></tr> |
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">DKFZp586M1622, DVL3, hCG_40299 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6zc7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6zc7 OCA], [https://pdbe.org/6zc7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6zc7 RCSB], [https://www.ebi.ac.uk/pdbsum/6zc7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6zc7 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Human]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Heinemann U]] | + | [[Category: Heinemann, U]] |
| - | [[Category: Oschkinat H]] | + | [[Category: Oschkinat, H]] |
| - | [[Category: Roske Y]] | + | [[Category: Roske, Y]] |
| + | [[Category: Dvl]] | ||
| + | [[Category: Inhibitor]] | ||
| + | [[Category: Pdz]] | ||
| + | [[Category: Peptide binding protein]] | ||
| + | [[Category: Signalling]] | ||
| + | [[Category: Wnt]] | ||
Revision as of 07:02, 20 July 2022
Small-molecule inhibitors of the PDZ domain of Dishevelled proteins interrupt Wnt signalling
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Categories: Human | Large Structures | Heinemann, U | Oschkinat, H | Roske, Y | Dvl | Inhibitor | Pdz | Peptide binding protein | Signalling | Wnt
