3uvt

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==Crystal structure of the third catalytic domain of ERp46==
==Crystal structure of the third catalytic domain of ERp46==
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<StructureSection load='3uvt' size='340' side='right' caption='[[3uvt]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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<StructureSection load='3uvt' size='340' side='right'caption='[[3uvt]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3uvt]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UVT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3UVT FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3uvt]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UVT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3UVT FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">TXNDC5, TLP46, UNQ364/PRO700 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">TXNDC5, TLP46, UNQ364/PRO700 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Protein_disulfide-isomerase Protein disulfide-isomerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.3.4.1 5.3.4.1] </span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Protein_disulfide-isomerase Protein disulfide-isomerase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.3.4.1 5.3.4.1] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3uvt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3uvt OCA], [http://pdbe.org/3uvt PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3uvt RCSB], [http://www.ebi.ac.uk/pdbsum/3uvt PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3uvt ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3uvt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3uvt OCA], [https://pdbe.org/3uvt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3uvt RCSB], [https://www.ebi.ac.uk/pdbsum/3uvt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3uvt ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/TXND5_HUMAN TXND5_HUMAN]] Possesses thioredoxin activity. Has been shown to reduce insulin disulfide bonds. Also complements protein disulfide-isomerase deficiency in yeast (By similarity).
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[[https://www.uniprot.org/uniprot/TXND5_HUMAN TXND5_HUMAN]] Possesses thioredoxin activity. Has been shown to reduce insulin disulfide bonds. Also complements protein disulfide-isomerase deficiency in yeast (By similarity).
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Human]]
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[[Category: Large Structures]]
[[Category: Protein disulfide-isomerase]]
[[Category: Protein disulfide-isomerase]]
[[Category: Gehring, K]]
[[Category: Gehring, K]]

Revision as of 08:11, 20 July 2022

Crystal structure of the third catalytic domain of ERp46

PDB ID 3uvt

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