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3uza
From Proteopedia
(Difference between revisions)
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==Thermostabilised Adenosine A2A receptor in complex with 6-(2,6-Dimethylpyridin-4-yl)-5-phenyl-1,2,4-triazin-3-amine== | ==Thermostabilised Adenosine A2A receptor in complex with 6-(2,6-Dimethylpyridin-4-yl)-5-phenyl-1,2,4-triazin-3-amine== | ||
| - | <StructureSection load='3uza' size='340' side='right' caption='[[3uza]], [[Resolution|resolution]] 3.27Å' scene=''> | + | <StructureSection load='3uza' size='340' side='right'caption='[[3uza]], [[Resolution|resolution]] 3.27Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3uza]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[3uza]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UZA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3UZA FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=T4G:6-(2,6-DIMETHYLPYRIDIN-4-YL)-5-PHENYL-1,2,4-TRIAZIN-3-AMINE'>T4G</scene></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=T4G:6-(2,6-DIMETHYLPYRIDIN-4-YL)-5-PHENYL-1,2,4-TRIAZIN-3-AMINE'>T4G</scene></td></tr> |
| - | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3uzc|3uzc]], [[3pwh|3pwh]], [[3rey|3rey]], [[3rfm|3rfm]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3uzc|3uzc]], [[3pwh|3pwh]], [[3rey|3rey]], [[3rfm|3rfm]]</div></td></tr> |
| - | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ADORA2A ([ | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ADORA2A ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3uza FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3uza OCA], [https://pdbe.org/3uza PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3uza RCSB], [https://www.ebi.ac.uk/pdbsum/3uza PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3uza ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/AA2AR_HUMAN AA2AR_HUMAN]] Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. |
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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==See Also== | ==See Also== | ||
| - | *[[Adenosine A2A receptor|Adenosine A2A receptor]] | + | *[[Adenosine A2A receptor 3D structures|Adenosine A2A receptor 3D structures]] |
== References == | == References == | ||
<references/> | <references/> | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Human]] | [[Category: Human]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Andrews, S P]] | [[Category: Andrews, S P]] | ||
[[Category: Congreve, M]] | [[Category: Congreve, M]] | ||
Revision as of 08:17, 20 July 2022
Thermostabilised Adenosine A2A receptor in complex with 6-(2,6-Dimethylpyridin-4-yl)-5-phenyl-1,2,4-triazin-3-amine
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Categories: Human | Large Structures | Andrews, S P | Congreve, M | Dore, A S | Hollenstein, K | Hurrell, E | Langmead, C J | Marshall, F H | Mason, J S | Ng, I W | Tehan, B | Weir, M | Zhukov, A | G-protein | Gpcr | Membrane protein | Signaling protein
