3v5r

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==Crystal structure of the unliganded form of Gal3p==
==Crystal structure of the unliganded form of Gal3p==
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<StructureSection load='3v5r' size='340' side='right' caption='[[3v5r]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
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<StructureSection load='3v5r' size='340' side='right'caption='[[3v5r]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3v5r]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Baker's_yeast Baker's yeast]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3V5R OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3V5R FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3v5r]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Baker's_yeast Baker's yeast]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3V5R OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3V5R FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3v2u|3v2u]], [[2aj4|2aj4]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3v2u|3v2u]], [[2aj4|2aj4]]</div></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">GAL3, YDR009W, YD8119.14 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=559292 Baker's yeast])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">GAL3, YDR009W, YD8119.14 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=559292 Baker's yeast])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3v5r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3v5r OCA], [http://pdbe.org/3v5r PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3v5r RCSB], [http://www.ebi.ac.uk/pdbsum/3v5r PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3v5r ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3v5r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3v5r OCA], [https://pdbe.org/3v5r PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3v5r RCSB], [https://www.ebi.ac.uk/pdbsum/3v5r PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3v5r ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/GAL3_YEAST GAL3_YEAST]] The GAL3 regulatory function is required for rapid induction of the galactose system. At normal induction, galactose in the presence of the GAL3 protein may lead to the induction of the GAL genes, including GAL1. Then the galactokinase protein (GAL1) in the presence of galactose may reinforce the induction leading to a higher expression level. Upon depletion of galactose, the inducing activity of the galactokinase protein may decrease, after which transcription of the GAL genes, including GAL1, may decrease.
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[[https://www.uniprot.org/uniprot/GAL3_YEAST GAL3_YEAST]] The GAL3 regulatory function is required for rapid induction of the galactose system. At normal induction, galactose in the presence of the GAL3 protein may lead to the induction of the GAL genes, including GAL1. Then the galactokinase protein (GAL1) in the presence of galactose may reinforce the induction leading to a higher expression level. Upon depletion of galactose, the inducing activity of the galactokinase protein may decrease, after which transcription of the GAL genes, including GAL1, may decrease.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</StructureSection>
</StructureSection>
[[Category: Baker's yeast]]
[[Category: Baker's yeast]]
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[[Category: Large Structures]]
[[Category: He, H]]
[[Category: He, H]]
[[Category: Joshua-Tor, L]]
[[Category: Joshua-Tor, L]]

Revision as of 08:33, 20 July 2022

Crystal structure of the unliganded form of Gal3p

PDB ID 3v5r

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