1ftn

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(New page: 200px<br /> <applet load="1ftn" size="450" color="white" frame="true" align="right" spinBox="true" caption="1ftn, resolution 2.1&Aring;" /> '''CRYSTAL STRUCTURE OF...)
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Revision as of 14:50, 12 November 2007

Image:1ftn.gif

1ftn, resolution 2.1Å

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CRYSTAL STRUCTURE OF THE HUMAN RHOA/GDP COMPLEX

Overview

RhoA, a ubiquitous intracellular GTPase, mediates cytoskeletal responses, to extracellular signals. A 2.1 A resolution crystal structure of the, human RhoA-GDP complex shows unique stereochemistry in the switch I, region, which results in a novel mode of Mg2+ binding.

About this Structure

1FTN is a Single protein structure of sequence from Homo sapiens with MG and GDP as ligands. Full crystallographic information is available from OCA.

Reference

Crystal structure of RhoA-GDP and its functional implications., Wei Y, Zhang Y, Derewenda U, Liu X, Minor W, Nakamoto RK, Somlyo AV, Somlyo AP, Derewenda ZS, Nat Struct Biol. 1997 Sep;4(9):699-703. PMID:9302995

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