8czv

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==Structure of MERS 3CL protease in complex with the cyclopropane based inhibitor 18d==
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==Structure of MERS 3CL protease in complex with the cyclopropane based inhibitor 17d==
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<StructureSection load='8czv' size='340' side='right'caption='[[8czv]]' scene=''>
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<StructureSection load='8czv' size='340' side='right'caption='[[8czv]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8CZV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8CZV FirstGlance]. <br>
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<table><tr><td colspan='2'>[[8czv]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8CZV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8CZV FirstGlance]. <br>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8czv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8czv OCA], [https://pdbe.org/8czv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8czv RCSB], [https://www.ebi.ac.uk/pdbsum/8czv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8czv ProSAT]</span></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=P8C:[(1~{S},2~{R})-2-[4,4-bis(fluoranyl)cyclohexyl]cyclopropyl]methyl+~{N}-[(2~{S})-1-[[(1~{R},2~{S})-1-[bis(oxidanyl)-oxidanylidene-$l^{5}-sulfanyl]-1-oxidanyl-3-[(3~{S})-2-oxidanylidenepyrrolidin-3-yl]propan-2-yl]amino]-4-methyl-1-oxidanylidene-pentan-2-yl]carbamate'>P8C</scene>, <scene name='pdbligand=PJR:[(1~{S},2~{R})-2-[4,4-bis(fluoranyl)cyclohexyl]cyclopropyl]methyl+~{N}-[(2~{S})-1-[[(1~{S},2~{S})-1-[bis(oxidanyl)-oxidanylidene-$l^{5}-sulfanyl]-1-oxidanyl-3-[(3~{S})-2-oxidanylidenepyrrolidin-3-yl]propan-2-yl]amino]-4-methyl-1-oxidanylidene-pentan-2-yl]carbamate'>PJR</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8czv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8czv OCA], [https://pdbe.org/8czv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8czv RCSB], [https://www.ebi.ac.uk/pdbsum/8czv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8czv ProSAT]</span></td></tr>
</table>
</table>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Battaile KP]]
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[[Category: Battaile, K P]]
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[[Category: Chamandi SD]]
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[[Category: Chamandi, S D]]
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[[Category: Chang KO]]
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[[Category: Chang, K O]]
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[[Category: Groutas WC]]
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[[Category: Groutas, W C]]
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[[Category: Kim Y]]
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[[Category: Kim, Y]]
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[[Category: Liu L]]
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[[Category: Liu, L]]
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[[Category: Lovell S]]
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[[Category: Lovell, S]]
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[[Category: Madden TK]]
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[[Category: Madden, T K]]
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[[Category: Nguyen HN]]
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[[Category: Nguyen, H N]]
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[[Category: Picard HR]]
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[[Category: Picard, H R]]
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[[Category: Thruman HA]]
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[[Category: Thruman, H A]]
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[[Category: Hydrolase]]
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[[Category: Hydrolase-hydrolase inhibitor complex]]
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[[Category: Mers 3cl protease inhhibitor]]
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[[Category: Protease]]
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[[Category: Severe acute respiratory syndrome coronavirus 2]]

Revision as of 05:05, 3 August 2022

Structure of MERS 3CL protease in complex with the cyclopropane based inhibitor 17d

PDB ID 8czv

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