3w2k

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==Structure of Trypanosoma cruzi dihydroorotate dehydrogenase in complex with MII-3-165==
==Structure of Trypanosoma cruzi dihydroorotate dehydrogenase in complex with MII-3-165==
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<StructureSection load='3w2k' size='340' side='right' caption='[[3w2k]], [[Resolution|resolution]] 1.54&Aring;' scene=''>
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<StructureSection load='3w2k' size='340' side='right'caption='[[3w2k]], [[Resolution|resolution]] 1.54&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3w2k]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Trycc Trycc]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3W2K OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3W2K FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3w2k]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Trycc Trycc]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3W2K OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3W2K FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=KRO:5-[2-(4-FLUORO-3-METHYLPHENYL)ETHYL]-2,6-DIOXO-1,2,3,6-TETRAHYDROPYRIMIDINE-4-CARBOXYLIC+ACID'>KRO</scene>, <scene name='pdbligand=NCO:COBALT+HEXAMMINE(III)'>NCO</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=KRO:5-[2-(4-FLUORO-3-METHYLPHENYL)ETHYL]-2,6-DIOXO-1,2,3,6-TETRAHYDROPYRIMIDINE-4-CARBOXYLIC+ACID'>KRO</scene>, <scene name='pdbligand=NCO:COBALT+HEXAMMINE(III)'>NCO</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3w1a|3w1a]], [[3w1l|3w1l]], [[3w1m|3w1m]], [[3w1n|3w1n]], [[3w1p|3w1p]], [[3w1q|3w1q]], [[3w1r|3w1r]], [[3w1t|3w1t]], [[3w1u|3w1u]], [[3w1x|3w1x]], [[3w22|3w22]], [[3w23|3w23]], [[3w2j|3w2j]], [[3w2l|3w2l]], [[3w2m|3w2m]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3w1a|3w1a]], [[3w1l|3w1l]], [[3w1m|3w1m]], [[3w1n|3w1n]], [[3w1p|3w1p]], [[3w1q|3w1q]], [[3w1r|3w1r]], [[3w1t|3w1t]], [[3w1u|3w1u]], [[3w1x|3w1x]], [[3w22|3w22]], [[3w23|3w23]], [[3w2j|3w2j]], [[3w2l|3w2l]], [[3w2m|3w2m]]</div></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PyrD ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=353153 TRYCC])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PyrD ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=353153 TRYCC])</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Dihydroorotate_oxidase_(fumarate) Dihydroorotate oxidase (fumarate)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.3.98.1 1.3.98.1] </span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Dihydroorotate_oxidase_(fumarate) Dihydroorotate oxidase (fumarate)], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.3.98.1 1.3.98.1] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3w2k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3w2k OCA], [http://pdbe.org/3w2k PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3w2k RCSB], [http://www.ebi.ac.uk/pdbsum/3w2k PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3w2k ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3w2k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3w2k OCA], [https://pdbe.org/3w2k PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3w2k RCSB], [https://www.ebi.ac.uk/pdbsum/3w2k PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3w2k ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/PYRD_TRYCC PYRD_TRYCC]] Catalyzes the conversion of dihydroorotate to orotate with fumarate as the electron acceptor. Molecular oxygen can replace fumarate in vitro.
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[[https://www.uniprot.org/uniprot/PYRD_TRYCC PYRD_TRYCC]] Catalyzes the conversion of dihydroorotate to orotate with fumarate as the electron acceptor. Molecular oxygen can replace fumarate in vitro.
==See Also==
==See Also==
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*[[Dihydroorotate dehydrogenase|Dihydroorotate dehydrogenase]]
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*[[Dihydroorotate dehydrogenase 3D structures|Dihydroorotate dehydrogenase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Large Structures]]
[[Category: Trycc]]
[[Category: Trycc]]
[[Category: Aoki, T]]
[[Category: Aoki, T]]

Revision as of 05:19, 3 August 2022

Structure of Trypanosoma cruzi dihydroorotate dehydrogenase in complex with MII-3-165

PDB ID 3w2k

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