3wcy

<StructureSection load='3wcy' size='340' side='right' caption='[[3wcy]], [[Resolution|resolution]] 2.90&Aring;' scene=''>

<table><tr><td colspan='2'>[[3wcy]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WCY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3WCY FirstGlance]. <br>

</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3s98|3s98]], [[3se3|3se3]], [[3se4|3se4]], [[1wu3|1wu3]], [[1au1|1au1]]</td></tr>

<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Ifar, Ifnar, Ifnar1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice]), Ifb, Ifnb, Ifnb1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3wcy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wcy OCA], [http://pdbe.org/3wcy PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3wcy RCSB], [http://www.ebi.ac.uk/pdbsum/3wcy PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3wcy ProSAT]</span></td></tr>

[[http://www.uniprot.org/uniprot/INAR1_MOUSE INAR1_MOUSE]] Associates with IFNAR2 to form the type I interferon receptor. Receptor for interferons alpha and beta. Binding to type I IFNs triggers tyrosine phosphorylation of a number of proteins including JAKs, TYK2, STAT proteins and IFNR alpha- and beta-subunits themselves. [[http://www.uniprot.org/uniprot/IFNB_MOUSE IFNB_MOUSE]] Has antiviral, antibacterial and anticancer activities.

*[[Interferon|Interferon]]

*[[Interferon receptor|Interferon receptor]]