2xq9

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<StructureSection load='2xq9' size='340' side='right'caption='[[2xq9]], [[Resolution|resolution]] 3.20&Aring;' scene=''>
<StructureSection load='2xq9' size='340' side='right'caption='[[2xq9]], [[Resolution|resolution]] 3.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2xq9]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Glovi Glovi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XQ9 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2XQ9 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2xq9]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Glovi Glovi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XQ9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2XQ9 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ARS:ARSENIC'>ARS</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ARS:ARSENIC'>ARS</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2xqa|2xqa]], [[2xq7|2xq7]], [[2xq5|2xq5]], [[2xq3|2xq3]], [[2xq8|2xq8]], [[2xq4|2xq4]], [[2xq6|2xq6]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2xqa|2xqa]], [[2xq7|2xq7]], [[2xq5|2xq5]], [[2xq3|2xq3]], [[2xq8|2xq8]], [[2xq4|2xq4]], [[2xq6|2xq6]]</div></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2xq9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xq9 OCA], [http://pdbe.org/2xq9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2xq9 RCSB], [http://www.ebi.ac.uk/pdbsum/2xq9 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2xq9 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2xq9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xq9 OCA], [https://pdbe.org/2xq9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2xq9 RCSB], [https://www.ebi.ac.uk/pdbsum/2xq9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2xq9 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/GLIC_GLOVI GLIC_GLOVI]] Cationic channel with similar permeabilities for Na(+) and K(+), that is activated by an increase of the proton concentration on the extracellular side. Displays no permeability for chloride ions. Shows slow kinetics of activation, no desensitization and a single channel conductance of 8 pS. Might contribute to adaptation to external pH change.<ref>PMID:17167423</ref>
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[[https://www.uniprot.org/uniprot/GLIC_GLOVI GLIC_GLOVI]] Cationic channel with similar permeabilities for Na(+) and K(+), that is activated by an increase of the proton concentration on the extracellular side. Displays no permeability for chloride ions. Shows slow kinetics of activation, no desensitization and a single channel conductance of 8 pS. Might contribute to adaptation to external pH change.<ref>PMID:17167423</ref>
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<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==

Revision as of 05:25, 10 August 2022

Pentameric ligand gated ion channel GLIC mutant E221A in complex with tetraethylarsonium (TEAs)

PDB ID 2xq9

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OCA

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