3wyg

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==Crystal structure of Xpo1p-PKI-Gsp1p-GTP complex==
==Crystal structure of Xpo1p-PKI-Gsp1p-GTP complex==
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<StructureSection load='3wyg' size='340' side='right' caption='[[3wyg]], [[Resolution|resolution]] 2.15&Aring;' scene=''>
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<StructureSection load='3wyg' size='340' side='right'caption='[[3wyg]], [[Resolution|resolution]] 2.15&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3wyg]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Baker's_yeast Baker's yeast] and [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WYG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3WYG FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3wyg]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Baker's_yeast Baker's yeast] and [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WYG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3WYG FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3wyf|3wyf]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3wyf|3wyf]]</div></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">AWRI796_3356 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=764097 Baker's yeast]), CRM1, G8514, KAP124, XPO1, YGR218W ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=559292 Baker's yeast]), PKIA, PRKACN1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">AWRI796_3356 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=764097 Baker's yeast]), CRM1, G8514, KAP124, XPO1, YGR218W ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=559292 Baker's yeast]), PKIA, PRKACN1 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3wyg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wyg OCA], [http://pdbe.org/3wyg PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3wyg RCSB], [http://www.ebi.ac.uk/pdbsum/3wyg PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3wyg ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3wyg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wyg OCA], [https://pdbe.org/3wyg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3wyg RCSB], [https://www.ebi.ac.uk/pdbsum/3wyg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3wyg ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/IPKA_HUMAN IPKA_HUMAN]] Extremely potent competitive inhibitor of cAMP-dependent protein kinase activity, this protein interacts with the catalytic subunit of the enzyme after the cAMP-induced dissociation of its regulatory chains. [[http://www.uniprot.org/uniprot/XPO1_YEAST XPO1_YEAST]] Receptor for the leucine-rich nuclear export signal (NES).
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[[https://www.uniprot.org/uniprot/IPKA_HUMAN IPKA_HUMAN]] Extremely potent competitive inhibitor of cAMP-dependent protein kinase activity, this protein interacts with the catalytic subunit of the enzyme after the cAMP-induced dissociation of its regulatory chains. [[https://www.uniprot.org/uniprot/XPO1_YEAST XPO1_YEAST]] Receptor for the leucine-rich nuclear export signal (NES).
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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==See Also==
==See Also==
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*[[CAMP-dependent protein kinase|CAMP-dependent protein kinase]]
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*[[CAMP-dependent protein kinase 3D structures|CAMP-dependent protein kinase 3D structures]]
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*[[Exportin|Exportin]]
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*[[Exportin 3D structures|Exportin 3D structures]]
== References ==
== References ==
<references/>
<references/>
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[[Category: Baker's yeast]]
[[Category: Baker's yeast]]
[[Category: Human]]
[[Category: Human]]
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[[Category: Large Structures]]
[[Category: Koyama, M]]
[[Category: Koyama, M]]
[[Category: Matsuura, Y]]
[[Category: Matsuura, Y]]

Revision as of 05:35, 10 August 2022

Crystal structure of Xpo1p-PKI-Gsp1p-GTP complex

PDB ID 3wyg

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