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3x0c

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==Crystal structure of PIP4KIIBETA I368A complex with GMP==
==Crystal structure of PIP4KIIBETA I368A complex with GMP==
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<StructureSection load='3x0c' size='340' side='right' caption='[[3x0c]], [[Resolution|resolution]] 2.55&Aring;' scene=''>
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<StructureSection load='3x0c' size='340' side='right'caption='[[3x0c]], [[Resolution|resolution]] 2.55&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3x0c]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3X0C OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3X0C FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3x0c]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3X0C OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3X0C FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=5GP:GUANOSINE-5-MONOPHOSPHATE'>5GP</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=5GP:GUANOSINE-5-MONOPHOSPHATE'>5GP</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3wzz|3wzz]], [[3x01|3x01]], [[3x02|3x02]], [[3x03|3x03]], [[3x04|3x04]], [[3x05|3x05]], [[3x06|3x06]], [[3x07|3x07]], [[3x08|3x08]], [[3x09|3x09]], [[3x0a|3x0a]], [[3x0b|3x0b]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3wzz|3wzz]], [[3x01|3x01]], [[3x02|3x02]], [[3x03|3x03]], [[3x04|3x04]], [[3x05|3x05]], [[3x06|3x06]], [[3x07|3x07]], [[3x08|3x08]], [[3x09|3x09]], [[3x0a|3x0a]], [[3x0b|3x0b]]</div></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PIP4K2B ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PIP4K2B ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/1-phosphatidylinositol-5-phosphate_4-kinase 1-phosphatidylinositol-5-phosphate 4-kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.149 2.7.1.149] </span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/1-phosphatidylinositol-5-phosphate_4-kinase 1-phosphatidylinositol-5-phosphate 4-kinase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.149 2.7.1.149] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3x0c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3x0c OCA], [http://pdbe.org/3x0c PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3x0c RCSB], [http://www.ebi.ac.uk/pdbsum/3x0c PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3x0c ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3x0c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3x0c OCA], [https://pdbe.org/3x0c PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3x0c RCSB], [https://www.ebi.ac.uk/pdbsum/3x0c PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3x0c ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/PI42B_HUMAN PI42B_HUMAN]] Participates in the biosynthesis of phosphatidylinositol 4,5-bisphosphate.<ref>PMID:9038203</ref>
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[[https://www.uniprot.org/uniprot/PI42B_HUMAN PI42B_HUMAN]] Participates in the biosynthesis of phosphatidylinositol 4,5-bisphosphate.<ref>PMID:9038203</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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[[Category: 1-phosphatidylinositol-5-phosphate 4-kinase]]
[[Category: 1-phosphatidylinositol-5-phosphate 4-kinase]]
[[Category: Human]]
[[Category: Human]]
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[[Category: Large Structures]]
[[Category: Asara, J A]]
[[Category: Asara, J A]]
[[Category: Cantley, L C]]
[[Category: Cantley, L C]]

Revision as of 05:37, 10 August 2022

Crystal structure of PIP4KIIBETA I368A complex with GMP

PDB ID 3x0c

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