3x29
From Proteopedia
(Difference between revisions)
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==CRYSTAL STRUCTURE of MOUSE CLAUDIN-19 IN COMPLEX with C-TERMINAL FRAGMENT OF CLOSTRIDIUM PERFRINGENS ENTEROTOXIN== | ==CRYSTAL STRUCTURE of MOUSE CLAUDIN-19 IN COMPLEX with C-TERMINAL FRAGMENT OF CLOSTRIDIUM PERFRINGENS ENTEROTOXIN== | ||
- | <StructureSection load='3x29' size='340' side='right' caption='[[3x29]], [[Resolution|resolution]] 3.70Å' scene=''> | + | <StructureSection load='3x29' size='340' side='right'caption='[[3x29]], [[Resolution|resolution]] 3.70Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
- | <table><tr><td colspan='2'>[[3x29]] is a 4 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[3x29]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_perfringens"_veillon_and_zuber_1898 "bacillus perfringens" veillon and zuber 1898] and [https://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3X29 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3X29 FirstGlance]. <br> |
- | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Cldn19 ([ | + | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Cldn19 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice]), cpe ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1502 "Bacillus perfringens" Veillon and Zuber 1898])</td></tr> |
- | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3x29 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3x29 OCA], [https://pdbe.org/3x29 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3x29 RCSB], [https://www.ebi.ac.uk/pdbsum/3x29 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3x29 ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
- | [[ | + | [[https://www.uniprot.org/uniprot/CLD19_MOUSE CLD19_MOUSE]] Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. [[https://www.uniprot.org/uniprot/ELTB_CLOPF ELTB_CLOPF]] This enterotoxin is responsible for many cases of a mild type of food poisoning. |
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Bacillus perfringens veillon and zuber 1898]] | [[Category: Bacillus perfringens veillon and zuber 1898]] | ||
+ | [[Category: Large Structures]] | ||
[[Category: Lk3 transgenic mice]] | [[Category: Lk3 transgenic mice]] | ||
[[Category: Fujiyoshi, Y]] | [[Category: Fujiyoshi, Y]] |
Revision as of 05:39, 10 August 2022
CRYSTAL STRUCTURE of MOUSE CLAUDIN-19 IN COMPLEX with C-TERMINAL FRAGMENT OF CLOSTRIDIUM PERFRINGENS ENTEROTOXIN
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Categories: Bacillus perfringens veillon and zuber 1898 | Large Structures | Lk3 transgenic mice | Fujiyoshi, Y | Irie, K | Nishikawa, K | Ogura, Y | Saitoh, Y | Suzuki, H | Tamura, A | Tani, K | Tsukita, S | Cell adhesion | Enterotoxin | Membrane protein | Receptor binding | Tight junction | Toxin-cell adhesion complex