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3zlf

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==Structure of group A Streptococcal enolase K312A mutant==
==Structure of group A Streptococcal enolase K312A mutant==
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<StructureSection load='3zlf' size='340' side='right' caption='[[3zlf]], [[Resolution|resolution]] 2.15&Aring;' scene=''>
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<StructureSection load='3zlf' size='340' side='right'caption='[[3zlf]], [[Resolution|resolution]] 2.15&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3zlf]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Strp6 Strp6]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZLF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ZLF FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3zlf]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Strp6 Strp6]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZLF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ZLF FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3zlg|3zlg]], [[3zlh|3zlh]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3zlg|3zlg]], [[3zlh|3zlh]]</div></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Phosphopyruvate_hydratase Phosphopyruvate hydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.11 4.2.1.11] </span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Phosphopyruvate_hydratase Phosphopyruvate hydratase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.11 4.2.1.11] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3zlf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zlf OCA], [http://pdbe.org/3zlf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3zlf RCSB], [http://www.ebi.ac.uk/pdbsum/3zlf PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3zlf ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3zlf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zlf OCA], [https://pdbe.org/3zlf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3zlf RCSB], [https://www.ebi.ac.uk/pdbsum/3zlf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3zlf ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/ENO_STRP6 ENO_STRP6]] Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. Binds plasminogen when expressed on the bacterial cell surface, potentially allowing the bacterium to acquire surface-associated proteolytic activity, which in turn contributes to tissue invasion and virulence.<ref>PMID:9603964</ref>
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[[https://www.uniprot.org/uniprot/ENO_STRP6 ENO_STRP6]] Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. Binds plasminogen when expressed on the bacterial cell surface, potentially allowing the bacterium to acquire surface-associated proteolytic activity, which in turn contributes to tissue invasion and virulence.<ref>PMID:9603964</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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==See Also==
==See Also==
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*[[Enolase|Enolase]]
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*[[Enolase 3D structures|Enolase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Large Structures]]
[[Category: Phosphopyruvate hydratase]]
[[Category: Phosphopyruvate hydratase]]
[[Category: Strp6]]
[[Category: Strp6]]

Revision as of 05:50, 10 August 2022

Structure of group A Streptococcal enolase K312A mutant

PDB ID 3zlf

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